The Enterotoxicity of Clostridium difficile Toxins

Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

(2010) Jeffrey Ng et al.   GASTROENTEROLOGY

Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury

(2010) Simon A. Hirota et al.   GASTROENTEROLOGY

Four Distinct Structural Domains in Clostridium difficile Toxin B Visualized Using SAXS

(2010) David Albesa-Jové et al.   JOURNAL OF MOLECULAR BIOLOGY

Clostridium difficile toxin A binds colonocyte Src causing dephosphorylation of focal adhesion kinase and paxillin

(2009) Ho Kim et al.   EXPERIMENTAL CELL RESEARCH

Antibiotic Treatment of Clostridium difficile Carrier Mice Triggers a Supershedder State, Spore-Mediated Transmission, and Severe Disease in Immunocompromised Hosts

(2009) T. D. Lawley et al.   INFECTION AND IMMUNITY

Structural Basis for Substrate Recognition in the Enzymatic Component of ADP-ribosyltransferase Toxin CDTa fromClostridium difficile

(2009) Amit Sundriyal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure-Function Analysis of Inositol Hexakisphosphate-induced Autoprocessing inClostridium difficileToxin A

(2009) Rory N. Pruitt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Piglet Models of Acute or ChronicClostridium difficileIllness

(2009) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

An ultrasensitive rapid immunocytotoxicity assay for detecting Clostridium difficile toxins

(2009) Xiangyun He et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Essential role of the glucosyltransferase activity in Clostridium difficile toxin-induced secretion of TNF-α by macrophages

(2009) Xingmin Sun et al.   MICROBIAL PATHOGENESIS

Toxin B is essential for virulence of Clostridium difficile

(2009) Dena Lyras et al.   NATURE

Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)

(2009) Brett A. Leav et al.   VACCINE

Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria

(2009) Carsten Schwan et al.   PLoS Pathogens

Tolevamer, an Anionic Polymer, Neutralizes Toxins Produced by the BI/027 Strains of Clostridium difficile

(2008) P. L. Hinkson et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aerial Dissemination of Clostridium difficilespores

(2008) Katherine Roberts et al.   BMC INFECTIOUS DISEASES

Essential role of toxin A inC. difficile027 and reference strain supernatant-mediated disruption of Caco-2 intestinal epithelial barrier function

(2008) P. A. Sutton et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Prevention of the cytopathic effect induced byClostridium difficileToxin B by active Rac1

(2008) Ismael Halabi-Cabezon et al.   FEBS LETTERS

A Mouse Model of Clostridium difficile–Associated Disease

(2008) Xinhua Chen et al.   GASTROENTEROLOGY

Human α-Defensins Inhibit Clostridium difficile Toxin B

(2008) Torsten Giesemann et al.   GASTROENTEROLOGY

Melanin-concentrating hormone (MCH) modulates C difficile toxin A-mediated enteritis in mice

(2008) E Kokkotou et al.   GUT

gp96 Is a Human Colonocyte Plasma Membrane Binding Protein for Clostridium difficile Toxin A

(2008) X. Na et al.   INFECTION AND IMMUNITY

Role of phospholipase A2and tyrosine kinase inClostridium difficiletoxin A-induced disruption of epithelial integrity, histologic inflammatory damage and intestinal secretion

(2008) Aldo A. M. Lima et al.   JOURNAL OF APPLIED TOXICOLOGY

Glucosylation of Rho GTPases by Clostridium difficile toxin A triggers apoptosis in intestinal epithelial cells

(2008) R. Gerhard et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Clostridium difficile toxin A promotes dendritic cell maturation and chemokine CXCL2 expression through p38, IKK, and the NF-κB signaling pathway

(2008) Jin Young Lee et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Structure and mode of action of clostridial glucosylating toxins: the ABCD model

(2008) Thomas Jank et al.   TRENDS IN MICROBIOLOGY

Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A

(2008) Claribel P. Taylor et al.   VACCINE

Emerging toxin A−B+ variant strain of Clostridium difficile responsible for pseudomembranous colitis at a tertiary care hospital in Korea

(2007) Bo-Moon Shin et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE