Article
Medicine, General & Internal
Park Manakul, Koopong Siribumrungwong, Naphakkhanith Dhanachanvisith
Summary: This study evaluated the short-term spinal sagittal alignment change after transforaminal epidural steroid injection (TFESI) in lumbar spinal stenosis patients. The results showed that TFESI significantly improves pain and sagittal alignment in these patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Anesthesiology
Pinyan Liu, Yitao Wu, Ziyu Xiao, Laura S. Gold, Patrick J. Heagerty, Thiru Annaswamy, Janna Friedly, Judith A. Turner, Jeffrey G. Jarvik, Pradeep Suri
Summary: This study used a risk-modeling approach to identify subgroups of patients with lumbar spinal stenosis who had different individualized treatment effects. A multivariable model was developed and validated to estimate predicted future back-related functional limitations, and patients from a randomized controlled trial were stratified into subgroups based on the predicted risk. The results showed a statistically significant modification of the treatment effect based on predicted risk quartile.
Article
Medicine, General & Internal
Minsoo Kim, Soyeon Cho, Yeonji Noh, Daehun Goh, Hee-Jeong Son, Jin Huh, Seong-Sik Kang, Byeongmun Hwang
Summary: This study examined the effects of epidural steroid injection (ESI) on pain scores and walking distance in patients with lumbar central spinal stenosis. The results showed that moderate stenosis patients had decreased pain scores and increased walking distance two weeks after the ESI, while severe stenosis patients had decreased pain scores with no significant change in walking distance. Patients with moderate stenosis achieved better outcomes than those with severe stenosis.
Article
Medicine, Research & Experimental
Akram Osman, Wei Hu, Jianhua-Sun, Jing Li, Xiao Luo, Nianrong Han, Ehsan Abduhani, Zhenqiang Liu
Summary: This study aims to compare the efficacy of caudal epidural steroid injections (CESIs) and selective nerve root blocks (SNRBs) in treating lumbar spinal stenosis (LSS). The findings are expected to guide clinicians in selecting the optimal treatment for LSS patients.
Article
Rehabilitation
Prakash Jayabalan, Rachel Bergman, Kevin Huang, Matthew Maas, Leah Welty
Summary: This study examined the relationship between socioeconomic status and pain reduction in patients with lumbar radiculopathy who underwent epidural steroid injections. The results showed that lower socioeconomic status was associated with greater pain reduction after the injection. Additionally, smoking and engaging in structured physical activity were also related to pain levels.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2023)
Article
Medicine, General & Internal
Minsoo Kim, Jiwon Bak, Daehun Goh, Jangho Bae, Kiyoung Shin, Hee-Jeong Son, Jin Huh, Seong-Sik Kang, Byeongmun Hwang
Summary: This study evaluated the effect of TFESI on pain scores and walking distance in patients with lumbar foraminal spinal stenosis. It found that TFESI significantly reduced pain scores and increased walking distance in patients after 4 weeks of treatment. However, patients with moderate disease severity had better pain relief outcomes and satisfaction compared to those with severe disease severity.
Article
Clinical Neurology
Gavin Kolodge, Laura S. Gold, Jeffrey G. Jarvik, Judith Turner, Ryan N. Hansen, Patrick J. Heagerty, Pradeep Suri, Janna Friedly
Summary: This study is a secondary analysis of a randomized controlled trial. The objective was to assess the impact of baseline treatment with opioids on pain and function in older adults with lumbar spinal stenosis who receive epidural injections. The results showed that baseline treatment with opioids did not have a significant association with pain and function outcomes.
Article
Clinical Neurology
Tyler M. Kreitz, John Mangan, Gregory D. Schroeder, Christopher K. Kepler, Mark F. Kurd, Kris E. Radcliff, Barrett Woods, Jeffery A. Rihn, D. Greg Anderson, Alexander R. Vaccaro, Alan S. Hilibrand
Summary: This retrospective study aimed to investigate the association between preoperative lumbar epidural corticosteroid injections (ESI) and infection after lumbar spine surgery. The results showed an increased risk of infection in patients undergoing fusion procedures with preoperative ESI, but not in those undergoing decompression only. Fusion, BMI, and CCI were identified as independent predictors of postoperative infection.
Article
Medicine, General & Internal
Piotr Godek, Kuba Ptaszkowski
Summary: This study evaluated the effectiveness of ultrasound-guided hyaluronic acid (HA) epidural injections combined with neuromobilization in the conservative treatment of lumbar foraminal stenosis (LFS). The treatment showed improvement in the straight leg raise (SLR) test results, but did not have significant effects on pain intensity, disability level, or functional assessment. Some patients experienced symptoms flare-up shortly after the injection, but without neurological deficits. Overall, this method has the potential to enhance the neurodynamics of nerve roots in LFS and provide an alternative to steroid treatment.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Anesthesiology
Shin Hyung Kim, Sang Jun Park, Kyung Bong Yoon, Eun-Kyung Jun, Jaehee Cho, Hee Jung Kim
Summary: This study found that pre-procedural handgrip strength can predict the analgesic efficacy after epidural steroid injection in elderly patients, while the psoas muscle index does not have this predictive role.
Article
Endocrinology & Metabolism
Shannon Clare, Alexander Dash, Yi Liu, Jonathan Harrison, Katelyn Vlastaris, Seth Waldman, Robert Griffin, Paul Cooke, Vijay Vad, Ellen Casey, Richard S. Bockman, Joseph Lane, Donald McMahon, Emily M. Stein
Summary: This study investigated the acute changes in bone turnover following epidural steroid injections (ESIs) in postmenopausal women. Results showed a significant decrease in bone formation markers one week after ESI, which lasted for at least 12 weeks. Further investigation into the long-term skeletal consequences of these injections is warranted, considering the large population of older adults who receive ESIs.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Anesthesiology
Maoying Wang, Hua Ling, Bixin Zheng, Li Song
Summary: This retrospective study aimed to determine the efficacy and predictors of transforaminal epidural steroid injection (TFESI) in elderly patients with lumbar radiculopathy. The study found that duration of symptoms, immediate postoperative response, and neutrophilic granulocyte percentage were predictors of a favorable response to TFESI. The study concluded that a short duration of symptoms, good immediate postoperative response, and high neutrophilic granulocyte percentage were long-term predictors of a good response to TFESI in elderly patients with lumbar radiculopathy.
Article
Surgery
Xiao Han, Derong Xu, ZhiNan Ren, Xin Chen, Zheng Li, Shugang Li
Summary: This study presented a severe case of lumbar spinal stenosis and spinal epidural lipomatosis, with outstanding clinical outcomes achieved by posterior decompression, internal fixation, and a modified articular fusion technique.
Article
Environmental Sciences
Massimiliano Carassiti, Giuseppe Pascarella, Alessandro Strumia, Fabrizio Russo, Giuseppe Francesco Papalia, Rita Cataldo, Francesca Gargano, Fabio Costa, Michelangelo Pierri, Francesca De Tommasi, Carlo Massaroni, Emiliano Schena, Felice Eugenio Agro
Summary: Epidural steroid injections (ESIs) are commonly used to treat lumbosacral radicular pain and can improve patients' quality of life, relieve pain, and reduce or delay the need for surgical intervention.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Review
Anesthesiology
Standiford Helm, Preston C. Harmon, Carl Noe, Aaron K. Calodney, Alaa Abd-Elsayed, Nebojsa Nick Knezevic, Gabor B. Racz
Summary: Transforaminal epidural injections have been used since the late 1990s to treat lumbar radicular pain. This study evaluated the effectiveness and safety of transforaminal injections for various conditions, finding Level I evidence supporting their use for radicular pain due to disc herniation.
Article
Medicine, Research & Experimental
Jeffrey G. Jarvik, Bryan A. Comstock, Kathryn T. James, Andrew L. Avins, Brian W. Bresnahan, Richard A. Deyo, Patrick H. Luetmer, Janna L. Friedly, Eric N. Meier, Daniel C. Cherldn, Laura S. Gold, Sean D. Rundell, Safwan S. Halabi, David F. Kallmes, Katherine W. Tan, Judith A. Turner, Lary G. Kessler, Danielle C. Lavallee, Kari A. Stephens, Patrick J. Heagerty
CONTEMPORARY CLINICAL TRIALS
(2015)
Article
Medicine, General & Internal
Jeffrey G. Jarvik, Laura S. Gold, Bryan A. Comstock, Patrick J. Heagerty, Sean D. Rundell, Judith A. Turner, Andrew L. Avins, Zoya Bauer, Brian W. Bresnahan, Janna L. Friedly, Kathryn James, Larry Kessler, Srdjan S. Nedeljkovic, David R. Nerenz, Xu Shi, Sean D. Sullivan, Leighton Chan, Jason M. Schwalb, Richard A. Deyo
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2015)
Article
Geriatrics & Gerontology
Sean D. Rundell, Karen J. Sherman, Patrick J. Heagerty, Charles N. Mock, Jeffrey G. Jarvik
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
(2015)
Article
Orthopedics
Sean D. Rundell, Adam P. Goode, Janna L. Friedly, Jeffrey G. Jarvik, Sean D. Sullivan, Brian W. Bresnahan
Article
Clinical Neurology
Sean D. Rundell, Alfred C. Gellhorn, Bryan A. Comstock, Patrick J. Heagerty, Janna L. Friedly, Jeffrey G. Jarvik
Article
Orthopedics
Grant S. Lipman, Brian J. Krabak, Sean D. Rundell, Katherine M. Shea, Natalie Badowski, Colin Little
CLINICAL JOURNAL OF SPORT MEDICINE
(2016)
Article
Medicine, Research & Experimental
Karin E. Johnson, Gila Neta, Laura M. Dember, Gloria D. Coronado, Jerry Suls, David A. Chambers, Sean Rundell, David H. Smith, Benmei Liu, Stephen Taplin, Catherine M. Stoney, Margaret M. Farrell, Russell E. Glasgow
Article
Health Care Sciences & Services
Sean D. Rundell, Laura S. Gold, Ryan N. Hansen, Brian W. Bresnahan
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
(2017)
Article
Rehabilitation
Alfred C. Gellhorn, Pradeep Suri, Sean D. Rundell, Nathan Olafsen, M. Jake Carlson, Steve Johnson, Adrielle Fry, Thiru M. Annaswamy, Christopher Gilligan, Bryan Comstock, Patrick Heagerty, Janna Friedly, Jeffrey G. Jarvik
Article
Radiology, Nuclear Medicine & Medical Imaging
W. Katherine Tan, Saeed Hassanpour, Patrick J. Heagerty, Sean D. Rundell, Pradeep Suri, Hannu T. Huhdanpaa, Kathryn James, David S. Carrell, Curtis P. Langlotz, Nancy L. Organ, Eric N. Meier, Karen J. Sherman, David F. Kallmes, Patrick H. Luetmer, Brent Griffith, David R. Nerenz, Jeffrey G. Jarvik
ACADEMIC RADIOLOGY
(2018)
Article
Rehabilitation
Pradeep Suri, Kristin Delaney, Sean D. Rundell, Daniel C. Cherkin
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2018)
Article
Health Care Sciences & Services
Sean D. Rundell, Brian W. Bresnahan, Patrick J. Heagerty, Bryan A. Comstock, Janna L. Friedly, Jeffrey G. Jarvik, Sean D. Sullivan
MEDICAL DECISION MAKING
(2014)
Article
Rehabilitation
Sean D. Rundell, Linda Resnik, Patrick J. Heagerty, Amit Kumar, Jeffrey G. Jarvik
Article
Rehabilitation
Jacob Kneeman, Samuel L. Battalio, Anna Korpak, Daniel C. Cherkin, Gang Luo, Sean D. Rundell, Pradeep Suri
Summary: STarT Back tool shows good discrimination (AUC = 0.79) for future persistent disabling LBP, but calibration was poor, underestimating the risk of persistent disabling LBP. Further updating of the tool may be needed for use in VA primary care.
Article
Orthopedics
Sean D. Rundell, Ayumi Saito, Eric N. Meier, Stephanie T. Danyluk, Jeffrey G. Jarvik, Kelley Seebeck, Janna L. Friedly, Patrick J. Heagerty, Sandra K. Johnston, Monica Smersh, Maggie E. Horn, Pradeep Suri, Amy M. Cizik, Adam P. Goode
Summary: This is a protocol for an inception cohort study of adults 50 years and older who are initiating non-surgical care for symptomatic LSS in a secondary care setting. The study aims to develop and evaluate a clinically useful model to predict long-term physical function of patients seeking non-surgical care for symptomatic LSS. Participants will be followed for 12 months, with data collected through telephone interviews, web-based surveys, and queries of electronic health records.
BMC MUSCULOSKELETAL DISORDERS
(2022)