BCKDH: The Missing Link in Apicomplexan Mitochondrial Metabolism Is Required for Full Virulence of Toxoplasma gondii and Plasmodium berghei

Phosphoenolpyruvate Carboxylase Identified as a Key Enzyme in Erythrocytic Plasmodium falciparum Carbon Metabolism

(2014) Janet Storm et al.   PLoS Pathogens

Mitochondrial metabolism of sexual and asexual blood stages of the malaria parasite Plasmodium falciparum

(2013) James I MacRae et al.   BMC BIOLOGY

Global proteomic analysis of the oocyst/sporozoite of Toxoplasma gondii reveals commitment to a host-independent lifestyle

(2013) Alessia Possenti et al.   BMC GENOMICS

Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates

(2013) J. Ning et al.   GENES & DEVELOPMENT

Kinetic Flux Profiling Elucidates Two Independent Acetyl-CoA Biosynthetic Pathways inPlasmodium falciparum

(2013) Simon A. Cobbold et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Global Mass Spectrometry Based Metabolomics Profiling of Erythrocytes Infected with Plasmodium falciparum

(2013) Theodore R. Sana et al.   PLoS One

Stable Isotope-Assisted Metabolomics for Network-Wide Metabolic Pathway Elucidation

(2012) Darren J. Creek et al.   ANALYTICAL CHEMISTRY

IDEOM: an Excel interface for analysis of LC–MS-based metabolomics data

(2012) Darren J. Creek et al.   BIOINFORMATICS

Substrate specificity in thiamin diphosphate-dependent decarboxylases

(2012) Forest H. Andrews et al.   BIOORGANIC CHEMISTRY

A Tetracycline-Repressible Transactivator System to Study Essential Genes in Malaria Parasites

(2012) Paco Pino et al.   Cell Host & Microbe

Mitochondrial Metabolism of Glucose and Glutamine Is Required for Intracellular Growth of Toxoplasma gondii

(2012) James I. MacRae et al.   Cell Host & Microbe

Lysine Acetylation Is Widespread on Proteins of Diverse Function and Localization in the Protozoan Parasite Toxoplasma gondii

(2012) Victoria Jeffers et al.   EUKARYOTIC CELL

Critical roles of the mitochondrial complex II in oocyst formation of rodent malaria parasite Plasmodium berghei

(2012) A. Hino et al.   JOURNAL OF BIOCHEMISTRY

Alveolate Mitochondrial Metabolic Evolution: Dinoflagellates Force Reassessment of the Role of Parasitism as a Driver of Change in Apicomplexans

(2012) Jillian C. Danne et al.   MOLECULAR BIOLOGY AND EVOLUTION

The 2-methylcitrate cycle is implicated in the detoxification of propionate inToxoplasma gondii

(2012) Julien Limenitakis et al.   MOLECULAR MICROBIOLOGY

Identification and Functional Expression of the Mitochondrial Pyruvate Carrier

(2012) S. Herzig et al.   SCIENCE

A Mitochondrial Pyruvate Carrier Required for Pyruvate Uptake in Yeast, Drosophila, and Humans

(2012) D. K. Bricker et al.   SCIENCE

Toward Global Metabolomics Analysis with Hydrophilic Interaction Liquid Chromatography–Mass Spectrometry: Improved Metabolite Identification by Retention Time Prediction

(2011) Darren J. Creek et al.   ANALYTICAL CHEMISTRY

Variation among Plasmodium falciparum Strains in Their Reliance on Mitochondrial Electron Transport Chain Function

(2011) Hangjun Ke et al.   EUKARYOTIC CELL

Arrested Oocyst Maturation inPlasmodiumParasites Lacking Type II NADH:Ubiquinone Dehydrogenase

(2011) Katja E. Boysen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isotopomer Profiling ofLeishmania mexicanaPromastigotes Reveals Important Roles for Succinate Fermentation and Aspartate Uptake in Tricarboxylic Acid Cycle (TCA) Anaplerosis, Glutamate Synthesis, and Growth

(2011) Eleanor C. Saunders et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acetylation Regulates Gluconeogenesis by Promoting PEPCK1 Degradation via Recruiting the UBR5 Ubiquitin Ligase

(2011) Wenqing Jiang et al.   MOLECULAR CELL

Exosomes from Plasmodium yoelii-Infected Reticulocytes Protect Mice from Lethal Infections

(2011) Lorena Martin-Jaular et al.   PLoS One

A constitutive pan-hexose permease for the Plasmodium life cycle and transgenic models for screening of antimalarial sugar analogs

(2010) Martin Blume et al.   FASEB JOURNAL

Life cycle studies of the hexose transporter ofPlasmodiumspecies and genetic validation of their essentiality

(2010) Ksenija Slavic et al.   MOLECULAR MICROBIOLOGY

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

(2010) Q. Wang et al.   SCIENCE

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Jalview Version 2--a multiple sequence alignment editor and analysis workbench

(2009) A. M. Waterhouse et al.   BIOINFORMATICS

The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume

(2009) L. Blanc et al.   BLOOD

Efficient Gene Replacements inToxoplasma gondiiStrains Deficient for Nonhomologous End Joining

(2009) Barbara A. Fox et al.   EUKARYOTIC CELL

Tagging of Endogenous Genes in aToxoplasma gondiiStrain Lacking Ku80

(2009) My-Hang Huynh et al.   EUKARYOTIC CELL

Toxoplasmosis: A history of clinical observations

(2009) Louis M. Weiss et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

13C-based metabolic flux analysis

(2009) Nicola Zamboni et al.   Nature Protocols

Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

(2009) M. Blume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation

(2009) K. E. Wellen et al.   SCIENCE

Toxoplasma Profilin Is Essential for Host Cell Invasion and TLR11-Dependent Induction of an Interleukin-12 Response

(2008) Fabienne Plattner et al.   Cell Host & Microbe

Apicomplexan mitochondrial metabolism: a story of gains, losses and retentions

(2008) Frank Seeber et al.   TRENDS IN PARASITOLOGY

Host Cell Egress and Invasion Induce Marked Relocations of Glycolytic Enzymes in Toxoplasma gondii Tachyzoites

(2008) Sebastien Pomel et al.   PLoS Pathogens

Structure-function relationships in the 2-oxo acid dehydrogenase family: Substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins

(2007) Victoria I. Bunik et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS