Plasmodium falciparum Erythrocyte Invasion: Combining Function with Immune Evasion

Electron tomography ofPlasmodium falciparummerozoites reveals core cellular events that underpin erythrocyte invasion

(2013) Eric Hanssen et al.   CELLULAR MICROBIOLOGY

Bacterially Expressed Full-Length Recombinant Plasmodium falciparum RH5 Protein Binds Erythrocytes and Elicits Potent Strain-Transcending Parasite-Neutralizing Antibodies

(2013) K. Sony Reddy et al.   INFECTION AND IMMUNITY

Neutralization of Plasmodium falciparum Merozoites by Antibodies against PfRH5

(2013) A. D. Douglas et al.   JOURNAL OF IMMUNOLOGY

Erythrocyte-Binding Antigens of Plasmodium falciparum Are Targets of Human Inhibitory Antibodies and Function To Evade Naturally Acquired Immunity

(2013) K. E. M. Persson et al.   JOURNAL OF IMMUNOLOGY

Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development

(2013) J. S. Richards et al.   JOURNAL OF IMMUNOLOGY

Naturally Acquired Antibodies Specific for Plasmodium falciparum Reticulocyte-Binding Protein Homologue 5 Inhibit Parasite Growth and Predict Protection From Malaria

(2013) Tuan M. Tran et al.   JOURNAL OF INFECTIOUS DISEASES

Plasmodium falciparum Merozoite Surface Antigen, PfRH5, Elicits Detectable Levels of Invasion-Inhibiting Antibodies in Humans

(2013) Saurabh D. Patel et al.   JOURNAL OF INFECTIOUS DISEASES

Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion

(2013) Daniel Y. Bargieri et al.   Nature Communications

Challenges of assessing the clinical efficacy of asexual blood-stagePlasmodium falciparummalaria vaccines

(2013) Susanne H Sheehy et al.   Human Vaccines & Immunotherapeutics

The role of the reticulocyte-binding-like protein homologues ofPlasmodiumin erythrocyte sensing and invasion

(2012) Karthigayan Gunalan et al.   CELLULAR MICROBIOLOGY

Transcriptional variation in the malaria parasite Plasmodium falciparum

(2012) N. Rovira-Graells et al.   GENOME RESEARCH

Identification of a Potent Combination of Key Plasmodium falciparum Merozoite Antigens That Elicit Strain-Transcending Parasite-Neutralizing Antibodies

(2012) Alok K. Pandey et al.   INFECTION AND IMMUNITY

A model for the progression of receptor–ligand interactions during erythrocyte invasion by Plasmodium falciparum

(2012) Katherine L. Harvey et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

The cellular and molecular basis for malaria parasite invasion of the human red blood cell

(2012) Alan F. Cowman et al.   JOURNAL OF CELL BIOLOGY

Molecular Basis of Allele-Specific Efficacy of a Blood-Stage Malaria Vaccine: Vaccine Development Implications

(2012) Amed Ouattara et al.   JOURNAL OF INFECTIOUS DISEASES

Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing

(2012) Magnus Manske et al.   NATURE

The Plasmodium falciparum Erythrocyte Invasion Ligand Pfrh4 as a Target of Functional and Protective Human Antibodies against Malaria

(2012) Linda Reiling et al.   PLoS One

A full-length recombinant Plasmodium falciparum PfRH5 protein induces inhibitory antibodies that are effective across common PfRH5 genetic variants

(2012) Leyla Y. Bustamante et al.   VACCINE

Population Genomic Scan for Candidate Signatures of Balancing Selection to Guide Antigen Characterization in Malaria Parasites

(2012) Alfred Amambua-Ngwa et al.   PLoS Genetics

Structural and Functional Insights into the Malaria Parasite Moving Junction Complex

(2012) Brigitte Vulliez-Le Normand et al.   PLoS Pathogens

Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

(2012) Andrew R. Williams et al.   PLoS Pathogens

Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte

(2011) David T. Riglar et al.   Cell Host & Microbe

Independent Roles of Apical Membrane Antigen 1 and Rhoptry Neck Proteins during Host Cell Invasion by Apicomplexa

(2011) Donatella Giovannini et al.   Cell Host & Microbe

Plasmodium falciparum 19-Kilodalton Merozoite Surface Protein 1 (MSP1)-Specific Antibodies That Interfere with Parasite GrowthIn VitroCan Inhibit MSP1 Processing, Merozoite Invasion, and Intracellular Parasite Development

(2011) David K. Moss et al.   INFECTION AND IMMUNITY

A Field Trial to Assess a Blood-Stage Malaria Vaccine

(2011) Mahamadou A. Thera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide

(2011) M. L. Tonkin et al.   SCIENCE

Erythrocyte and reticulocyte binding-like proteins of Plasmodium falciparum

(2011) Wai-Hong Tham et al.   TRENDS IN PARASITOLOGY

The blood-stage malaria antigen PfRH5 is susceptible to vaccine-inducible cross-strain neutralizing antibody

(2011) Alexander D. Douglas et al.   Nature Communications

An EGF-like Protein Forms a Complex with PfRh5 and Is Required for Invasion of Human Erythrocytes by Plasmodium falciparum

(2011) Lin Chen et al.   PLoS Pathogens

The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

(2011) Mauld Lamarque et al.   PLoS Pathogens

Association between Naturally Acquired Antibodies to Erythrocyte‐Binding Antigens ofPlasmodium falciparumand Protection from Malaria and High‐Density Parasitemia

(2010) Jack S. Richards et al.   CLINICAL INFECTIOUS DISEASES

Reticulocyte and Erythrocyte Binding-Like Proteins Function Cooperatively in Invasion of Human Erythrocytes by Malaria Parasites

(2010) Sash Lopaticki et al.   INFECTION AND IMMUNITY

Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

(2010) Dave Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence That the Erythrocyte Invasion Ligand PfRh2 is a Target of Protective Immunity against Plasmodium falciparum Malaria

(2010) L. Reiling et al.   JOURNAL OF IMMUNOLOGY

Erythrocyte Invasion and Merozoite Ligand Gene Expression in Severe and MildPlasmodium falciparumMalaria

(2010) Natalia Gomez‐Escobar et al.   JOURNAL OF INFECTIOUS DISEASES

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

(2010) Freya J. I. Fowkes et al.   PLOS MEDICINE

Distinct External Signals Trigger Sequential Release of Apical Organelles during Erythrocyte Invasion by Malaria Parasites

(2010) Shailja Singh et al.   PLoS Pathogens

Cooperativity betweenPlasmodium falciparumadhesive proteins for invasion into erythrocytes

(2009) Tiffany M. DeSimone et al.   MOLECULAR MICROBIOLOGY

Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

(2009) Bernhards R. Ogutu et al.   PLoS One

The merozoite has landed: reticulocyte-binding-like ligands and the specificity of erythrocyte recognition

(2009) Julian C. Rayner   TRENDS IN PARASITOLOGY

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

(2009) Issaka Sagara et al.   VACCINE

An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery

(2009) Christine R. Collins et al.   PLoS Pathogens

Erythrocyte Binding Protein PfRH5 Polymorphisms Determine Species-Specific Pathways of Plasmodium falciparum Invasion

(2008) Karen Hayton et al.   Cell Host & Microbe

Large-scale screening for novel low-affinity extracellular protein interactions

(2008) K. M. Bushell et al.   GENOME RESEARCH

A Diversity-Covering Approach to Immunization with Plasmodium falciparum Apical Membrane Antigen 1 Induces Broader Allelic Recognition and Growth Inhibition Responses in Rabbits

(2008) E. J. Remarque et al.   INFECTION AND IMMUNITY

Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

(2008) Jake Baum et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

(2008) Paul R. Gilson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites

(2008) Jun Cao et al.   PARASITOLOGY INTERNATIONAL