Syk Signaling in Dendritic Cells Orchestrates Innate Resistance to Systemic Fungal Infection

IL-17 Regulates Systemic Fungal Immunity by Controlling the Functional Competence of NK Cells

(2014) Eva Bär et al.   IMMUNITY

The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans

(2014) C. A. Wells et al.   JOURNAL OF IMMUNOLOGY

Invasive fungal infection and impaired neutrophil killing in human CARD9 deficiency

(2013) A. Drewniak et al.   BLOOD

Genetic Tracing via DNGR-1 Expression History Defines Dendritic Cells as a Hematopoietic Lineage

(2013) Barbara U. Schraml et al.   CELL

C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection

(2013) Le-Le Zhu et al.   IMMUNITY

Natural killer cell deficiency

(2013) Jordan S. Orange   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

(2013) Michail S. Lionakis et al.   JOURNAL OF CLINICAL INVESTIGATION

Resident Renal Mononuclear Phagocytes Comprise Five Discrete Populations with Distinct Phenotypes and Functions

(2013) T. Kawakami et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Monocytes Mediate Early and Organ-Specific Innate Defense During Systemic Candidiasis

(2013) Lisa Y. Ngo et al.   JOURNAL OF INFECTIOUS DISEASES

Candida and Host Determinants of Susceptibility to Invasive Candidiasis

(2013) Michail S. Lionakis et al.   PLoS Pathogens

Dendritic Cell Derived Cytokines in Human Natural Killer Cell Differentiation and Activation

(2013) Obinna Chijioke et al.   Frontiers in Immunology

Candida albicans Infection Affords Protection against Reinfection via Functional Reprogramming of Monocytes

(2012) Jessica Quintin et al.   Cell Host & Microbe

Immunity to infection in IL-17-deficient mice and humans

(2012) Sophie Cypowyj et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Toll-like Receptor 1 Polymorphisms Increase Susceptibility to Candidemia

(2012) Theo S. Plantinga et al.   JOURNAL OF INFECTIOUS DISEASES

Functionally relevant neutrophilia in CD11c diphtheria toxin receptor transgenic mice

(2012) André P Tittel et al.   NATURE METHODS

Hidden Killers: Human Fungal Infections

(2012) G. D. Brown et al.   Science Translational Medicine

Chemokine Receptor Ccr1 Drives Neutrophil-Mediated Kidney Immunopathology and Mortality in Invasive Candidiasis

(2012) Michail S. Lionakis et al.   PLoS Pathogens

Innate Antifungal Immunity: The Key Role of Phagocytes

(2011) Gordon D. Brown   Annual Review of Immunology

Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense

(2011) Fabiola Osorio et al.   IMMUNITY

Protective Role of Naturally Occurring Interleukin-17A-Producing γδ T Cells in the Lung at the Early Stage of Systemic Candidiasis in Mice

(2011) Takashi Dejima et al.   INFECTION AND IMMUNITY

The Renal Mononuclear Phagocytic System

(2011) P. J. Nelson et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Syk-coupled C-type lectins in immunity

(2011) Ann M. Kerrigan et al.   TRENDS IN IMMUNOLOGY

Cytokine-activated NK cells inhibit PMN apoptosis and preserve their functional capacity

(2010) N. Bhatnagar et al.   BLOOD

Dectin-2 Recognition of α-Mannans and Induction of Th17 Cell Differentiation Is Essential for Host Defense against Candida albicans

(2010) Shinobu Saijo et al.   IMMUNITY

Features of the dendritic cell lineage

(2010) Ralph M. Steinman et al.   IMMUNOLOGICAL REVIEWS

Neutrophil activation and survival are modulated by interaction with NK cells

(2010) C. Costantini et al.   INTERNATIONAL IMMUNOLOGY

Calcineurin regulates innate antifungal immunity in neutrophils

(2010) Matthew B. Greenblatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-23 and IL-17A, but Not IL-12 and IL-22, Are Required for Optimal Skin Host Defense against Candida albicans

(2010) S. Kagami et al.   JOURNAL OF IMMUNOLOGY

Organ-Specific Innate Immune Responses in a Mouse Model of Invasive Candidiasis

(2010) Michail S. Lionakis et al.   Journal of Innate Immunity

IL-22 defines a novel immune pathway of antifungal resistance

(2010) A De Luca et al.   Mucosal Immunology

An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans

(2009) Amy G. Hise et al.   Cell Host & Microbe

Epidemiology and Outcomes of Candidemia in 2019 Patients: Data from the Prospective Antifungal Therapy Alliance Registry

(2009) David L. Horn et al.   CLINICAL INFECTIOUS DISEASES

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dectin-1 is required for human dendritic cells to initiate immune response to Candida albicans through Syk activation

(2009) Franck Skrzypek et al.   MICROBES AND INFECTION

Identification of a dendritic cell receptor that couples sensing of necrosis to immunity

(2009) David Sancho et al.   NATURE

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

(2009) Olaf Gross et al.   NATURE

Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections

(2009) Bart Ferwerda et al.   NEW ENGLAND JOURNAL OF MEDICINE

A HomozygousCARD9Mutation in a Family with Susceptibility to Fungal Infections

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pathogen specific cytokine release reveals an effect of TLR2 Arg753Gln during Candida sepsis in humans

(2008) Tobias Woehrle et al.   CYTOKINE

Toll-like Receptors Activate Innate and Adaptive Immunity by using Dendritic Cell-Intrinsic and -Extrinsic Mechanisms

(2008) Baidong Hou et al.   IMMUNITY

Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes

(2008) Claudia Jakubzick et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mincle is an ITAM-coupled activating receptor that senses damaged cells

(2008) Sho Yamasaki et al.   NATURE IMMUNOLOGY

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE