The Triggering Receptor Expressed on Myeloid Cells 2 Inhibits Complement Component 1q Effector Mechanisms and Exerts Detrimental Effects during Pneumococcal Pneumonia

Triggering Receptor Expressed on Myeloid Cells-2 Protects against Polymicrobial Sepsis by Enhancing Bacterial Clearance

(2013) QiXing Chen et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage

(2013) Patrick Wunderlich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Alternative Role of C1q in Bacterial Infections: Facilitating Streptococcus pneumoniae Adherence and Invasion of Host Cells

(2013) V. Agarwal et al.   JOURNAL OF IMMUNOLOGY

The Scavenger Receptor CD36 Downmodulates the Early Inflammatory Response while Enhancing Bacterial Phagocytosis during Pneumococcal Pneumonia

(2013) O. Sharif et al.   JOURNAL OF IMMUNOLOGY

Attenuated Inflammatory Response in Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Knock-Out Mice following Stroke

(2013) Matthias W. Sieber et al.   PLoS One

Bacterial Sensor Triggering Receptor Expressed on Myeloid Cells-2 Regulates the Mucosal Inflammatory Response

(2012) Carmen Correale et al.   GASTROENTEROLOGY

TREM2 and  -Catenin Regulate Bone Homeostasis by Controlling the Rate of Osteoclastogenesis

(2012) K. Otero et al.   JOURNAL OF IMMUNOLOGY

Identification of TLT2 as an Engulfment Receptor for Apoptotic Cells

(2012) A. de Freitas et al.   JOURNAL OF IMMUNOLOGY

Variant TREM2 as Risk Factor for Alzheimer's Disease

(2012) Harald Neumann et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phagosomal Degradation Increases TLR Access to Bacterial Ligands and Enhances Macrophage Sensitivity to Bacteria

(2011) A. J. Wolf et al.   JOURNAL OF IMMUNOLOGY

Protective Role of Peroxisome Proliferator–activated Receptor-β/δ in Septic Shock

(2010) Amar Kapoor et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Classical and Regulatory Functions of C1q in Immunity and Autoimmunity

(2010) Jinhua Lu et al.   Cellular & Molecular Immunology

Phagocytosis and Phagosome Acidification Are Required for Pathogen Processing and MyD88-Dependent Responses to Staphylococcus aureus

(2010) W. K. E. Ip et al.   JOURNAL OF IMMUNOLOGY

Myeloid PTEN Promotes Inflammation but Impairs Bactericidal Activities during Murine Pneumococcal Pneumonia

(2010) G. Schabbauer et al.   JOURNAL OF IMMUNOLOGY

Serotype 19A Is the Most Common Serotype Causing Invasive Pneumococcal Infections in Children

(2010) S. L. Kaplan et al.   PEDIATRICS

Vasoactive intestinal peptide re-balances TREM-1/TREM-2 ratio in acute lung injury

(2010) Guo-Ying Sun et al.   REGULATORY PEPTIDES

Mechanisms of Neutrophil Accumulation in the Lungs Against Bacteria

(2009) Gayathriy Balamayooran et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

(2009) Elsa-Noah N'Diaye et al.   JOURNAL OF CELL BIOLOGY

TREM-1 Activation Alters the Dynamics of Pulmonary IRAK-M Expression In Vivo and Improves Host Defense during Pneumococcal Pneumonia

(2009) H. Lagler et al.   JOURNAL OF IMMUNOLOGY

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

(2009) Christine L. Hsieh et al.   JOURNAL OF NEUROCHEMISTRY

Pathogenesis, treatment, and prevention of pneumococcal pneumonia

(2009) Tom van der Poll et al.   LANCET

Cross-regulation of signaling by ITAM-associated receptors

(2009) Lionel B Ivashkiv   NATURE IMMUNOLOGY

PPAR-δ senses and orchestrates clearance of apoptotic cells to promote tolerance

(2009) Lata Mukundan et al.   NATURE MEDICINE

Emerging roles of peroxisome proliferator-activated receptor-β/δ in inflammation

(2009) David Bishop-Bailey et al.   PHARMACOLOGY & THERAPEUTICS

From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection

(2008) Omar Sharif et al.   IMMUNOBIOLOGY

Inhibition of pulmonary antibacterial defense by interferon-γ during recovery from influenza infection

(2008) Keer Sun et al.   NATURE MEDICINE