Identification of the Microsporidian Encephalitozoon cuniculi as a New Target of the IFNγ-Inducible IRG Resistance System

The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy

(2014) Jayoung Choi et al.   IMMUNITY

Chlamydia muridarum Evades Growth Restriction by the IFN-γ-Inducible Host Resistance Factor Irgb10

(2014) Jörn Coers et al.   JOURNAL OF IMMUNOLOGY

Avirulent strains of Toxoplasma gondii infect macrophages by active invasion from the phagosome

(2014) Y. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Shared Signatures of Parasitism and Phylogenomics Unite Cryptomycota and Microsporidia

(2013) Timothy Y. James et al.   CURRENT BIOLOGY

Irgm1 (LRG-47), a Regulator of Cell-Autonomous Immunity, Does Not Localize to Mycobacterial or Listerial Phagosomes in IFN- -Induced Mouse Cells

(2013) H. M. Springer et al.   JOURNAL OF IMMUNOLOGY

IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins

(2013) Arun K. Haldar et al.   PLoS Pathogens

Guanylate-binding Protein 1 (Gbp1) Contributes to Cell-autonomous Immunity against Toxoplasma gondii

(2013) Elizabeth M. Selleck et al.   PLoS Pathogens

Reciprocal virulence and resistance polymorphism in the relationship between Toxoplasma gondii and the house mouse

(2013) Jingtao Lilue et al.   eLife

Phylogenomics supports microsporidia as the earliest diverging clade of sequenced fungi

(2012) Salvador Capella-Gutiérrez et al.   BMC BIOLOGY

Toxofilin upregulates the host cortical actin cytoskeleton dynamics, facilitating Toxoplasma invasion

(2012) V. Delorme-Walker et al.   JOURNAL OF CELL SCIENCE

Antimicrobial effects of murine mesenchymal stromal cells directed against Toxoplasma gondii and Neospora caninum: role of immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs)

(2012) K. Spekker et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy

(2012) Adam James Reid et al.   PLoS Pathogens

The IRG protein-based resistance mechanism in mice and its relation to virulence in Toxoplasma gondii

(2011) Jonathan C Howard et al.   CURRENT OPINION IN MICROBIOLOGY

The parasitophorous vacuole of Encephalitozoon cuniculi: Biogenesis and characteristics of the host cell–pathogen interface

(2011) Wolfgang Bohne et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Molecular identification and genotyping of Microsporidia in selected hosts

(2011) Alexandra Valencakova et al.   PARASITOLOGY RESEARCH

The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens

(2011) Oliver Liesenfeld et al.   PLoS One

Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication

(2011) Jessica S. Tyler et al.   TRENDS IN PARASITOLOGY

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole

(2010) Aliaksandr Khaminets et al.   CELLULAR MICROBIOLOGY

Reactive nitrogen and oxygen species, and iron sequestration contribute to macrophage-mediated control of Encephalitozoon cuniculi (Phylum Microsporidia) infection in vitro and in vivo

(2010) Elizabeth S. Didier et al.   MICROBES AND INFECTION

Germination of phagocytosed E. cuniculi spores does not significantly contribute to parasitophorous vacuole formation in J774 cells

(2010) Johanna Orlik et al.   PARASITOLOGY RESEARCH

The Mouse Resistance Protein Irgm1 (LRG-47): A Regulator or an Effector of Pathogen Defense?

(2010) Julia P. Hunn et al.   PLoS Pathogens

Host Cell Entry by Apicomplexa Parasites Requires Actin Polymerization in the Host Cell

(2009) Virginie Gonzalez et al.   Cell Host & Microbe

Virulent Toxoplasma gondii Evade Immunity-Related GTPase-Mediated Parasite Vacuole Disruption within Primed Macrophages

(2009) Y. Zhao et al.   JOURNAL OF IMMUNOLOGY

Balance of Irgm protein activities determines IFN-γ-induced host defense

(2009) Stanley C. Henry et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IFN-γ-Inducible Irga6 Mediates Host Resistance against Chlamydia trachomatis via Autophagy

(2009) Munir A. Al-Zeer et al.   PLoS One

Disruption of the Toxoplasma gondii Parasitophorous Vacuole by IFNγ-Inducible Immunity-Related GTPases (IRG Proteins) Triggers Necrotic Cell Death

(2009) Yang O. Zhao et al.   PLoS Pathogens

Autophagosome-Independent Essential Function for the Autophagy Protein Atg5 in Cellular Immunity to Intracellular Pathogens

(2008) Zijiang Zhao et al.   Cell Host & Microbe

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii

(2008) Julia P Hunn et al.   EMBO JOURNAL

The Nascent Parasitophorous Vacuole Membrane ofEncephalitozoon cuniculiIs Formed by Host Cell Lipids and Contains Pores Which Allow Nutrient Uptake

(2008) Karin Rönnebäumer et al.   EUKARYOTIC CELL

The Gamma Interferon (IFN- )-Inducible GTP-Binding Protein IGTP Is Necessary for Toxoplasma Vacuolar Disruption and Induces Parasite Egression in IFN- -Stimulated Astrocytes

(2008) T. Melzer et al.   INFECTION AND IMMUNITY

Inactive and Active States of the Interferon-inducible Resistance GTPase, Irga6,in Vivo

(2008) Natasa Papic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinetics of Encephalitozoon Spp. Infection of Human Macrophages

(2008) Jeffrey Fischer et al.   JOURNAL OF PARASITOLOGY

Interferon-γ-mediated activation of enterocytes in immunological control ofEncephalitozoon intestinalisinfection

(2008) N. CHOUDHRY et al.   PARASITE IMMUNOLOGY