Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques

标题
Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques
作者
关键词
Antibodies, Dengue virus, Mosquitoes, Immune response, Vaccines, Microbial mutation, Mouse models, Viremia
出版物
PLoS Pathogens
Volume 9, Issue 8, Pages e1003521
出版商
Public Library of Science (PLoS)
发表日期
2013-08-02
DOI
10.1371/journal.ppat.1003521

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