The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells

Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques

(2014) R. Halwani et al.   JOURNAL OF IMMUNOLOGY

Peginterferon-α does not improve early peripheral blood HBV-specific T-cell responses in HBeAg-negative chronic hepatitis

(2012) Amalia Penna et al.   JOURNAL OF HEPATOLOGY

Signal 3 requirement for memory CD8+T-cell activation is determined by the infectious pathogen

(2011) Selina J. Keppler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection

(2011) Anna Schurich et al.   HEPATOLOGY

Contribution of Herpesvirus Specific CD8 T Cells to Anti-Viral T Cell Response in Humans

(2010) Elena Sandalova et al.   PLoS Pathogens

Reciprocal responsiveness to interleukin-12 and interferon-  specifies human CD8+ effector versus central memory T-cell fates

(2009) H. J. Ramos et al.   BLOOD

Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

(2009) Paola Fisicaro et al.   GASTROENTEROLOGY

Cell-Intrinsic Transforming Growth Factor-β Signaling Mediates Virus-Specific CD8+ T Cell Deletion and Viral Persistence In Vivo

(2009) Roberto Tinoco et al.   IMMUNITY

Semliki Forest Virus Expressing Interleukin-12 Induces Antiviral and Antitumoral Responses in Woodchucks with Chronic Viral Hepatitis and Hepatocellular Carcinoma

(2009) J. R. Rodriguez-Madoz et al.   JOURNAL OF VIROLOGY

Intrahepatic Murine CD8 T-Cell Activation Associates With a Distinct Phenotype Leading to Bim-Dependent Death

(2008) Lauren E. Holz et al.   GASTROENTEROLOGY

Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection

(2008) A. Ross Lopes et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection

(2008) Abhishek Das et al.   JOURNAL OF EXPERIMENTAL MEDICINE