IL-27 Receptor Signalling Restricts the Formation of Pathogenic, Terminally Differentiated Th1 Cells during Malaria Infection by Repressing IL-12 Dependent Signals

IL-12 Signaling Drives CD8 + T Cell IFN-γ Production and Differentiation of KLRG1 + Effector Subpopulations during Toxoplasma gondii Infection

(2014) Douglas C. Wilson et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-27 Is a Potent Inducer of IL-10 but Not FoxP3 in Murine T Cells

(2014) M. Batten et al.   JOURNAL OF IMMUNOLOGY

The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology

(2012) Aisling O’Hara Hall et al.   IMMUNITY

CD8α+ Dendritic Cells Are the Critical Source of Interleukin-12 that Controls Acute Infection by Toxoplasma gondii Tachyzoites

(2011) Mona Mashayekhi et al.   IMMUNITY

A Role for IL-27 in Limiting T Regulatory Cell Populations

(2011) E. D. Tait Wojno et al.   JOURNAL OF IMMUNOLOGY

IL-27 Promotes IL-10 Production by Effector Th1 CD4+ T Cells: A Critical Mechanism for Protection from Severe Immunopathology during Malaria Infection

(2011) A. P. Freitas do Rosario et al.   JOURNAL OF IMMUNOLOGY

Two modes of immune suppression by Foxp3+ regulatory T cells under inflammatory or non-inflammatory conditions

(2011) Tomoyuki Yamaguchi et al.   SEMINARS IN IMMUNOLOGY

Prolonged Interleukin-2Rα Expression on Virus-Specific CD8+ T Cells Favors Terminal-Effector Differentiation In Vivo

(2010) Vandana Kalia et al.   IMMUNITY

Interleukin-2 and Inflammation Induce Distinct Transcriptional Programs that Promote the Differentiation of Effector Cytolytic T Cells

(2010) Matthew E. Pipkin et al.   IMMUNITY

IL-27 promotes T cell–dependent colitis through multiple mechanisms

(2010) Jennifer H. Cox et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Essential Role for IL-27 Receptor Signaling in Prevention of Th1-Mediated Immunopathology during Malaria Infection

(2010) E. G. Findlay et al.   JOURNAL OF IMMUNOLOGY

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27

(2010) Lionel Apetoh et al.   NATURE IMMUNOLOGY

Effector T cell plasticity: flexibility in the face of changing circumstances

(2010) Kenneth M Murphy et al.   NATURE IMMUNOLOGY

CD4+ Natural Regulatory T Cells Prevent Experimental Cerebral Malaria via CTLA-4 When Expanded In Vivo

(2010) Ashraful Haque et al.   PLoS Pathogens

Transcriptional Repressor Blimp-1 Promotes CD8+ T Cell Terminal Differentiation and Represses the Acquisition of Central Memory T Cell Properties

(2009) Rachel L. Rutishauser et al.   IMMUNITY

Decrease of Foxp3+ Treg Cell Number and Acquisition of Effector Cell Phenotype during Lethal Infection

(2009) Guillaume Oldenhove et al.   IMMUNITY

Regulation of immune responses by interleukin-27

(2009) Hiroki Yoshida et al.   IMMUNOLOGICAL REVIEWS

Differential Effect of IL-27 on Developing versus Committed Th17 Cells

(2009) M. El-behi et al.   JOURNAL OF IMMUNOLOGY

Limited Role of CD4+Foxp3+ Regulatory T Cells in the Control of Experimental Cerebral Malaria

(2009) C. Steeg et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-27 Induces the Transcription Factor c-Maf, Cytokine IL-21, and the Costimulatory Receptor ICOS that Coordinately Act Together to Promote Differentiation of IL-10-Producing Tr1 Cells

(2009) C. Pot et al.   JOURNAL OF IMMUNOLOGY

IL-27 Blocks RORc Expression to Inhibit Lineage Commitment of Th17 Cells

(2009) C. Diveu et al.   JOURNAL OF IMMUNOLOGY

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

(2009) Meghan A Koch et al.   NATURE IMMUNOLOGY

CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses

(2009) J. J. Obar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heroes or villains? T regulatory cells in malaria infection

(2009) Anja Scholzen et al.   TRENDS IN PARASITOLOGY

IL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response

(2008) M. P. Rubinstein et al.   BLOOD

IL-10 from CD4+CD25−Foxp3−CD127− Adaptive Regulatory T Cells Modulates Parasite Clearance and Pathology during Malaria Infection

(2008) Kevin N. Couper et al.   PLoS Pathogens