Sustained Activation of Akt Elicits Mitochondrial Dysfunction to Block Plasmodium falciparum Infection in the Mosquito Host

Organ-specific mediation of lifespan extension: More than a gut feeling?

(2012) Michael Rera et al.   AGEING RESEARCH REVIEWS

Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State

(2012) Isabel Garcia-Cao et al.   CELL

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

JNK/FOXO mediated PeroxiredoxinV expression regulates redox homeostasis during Drosophila melanogaster gut infection

(2012) Hye-Mi Ahn et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Ingested Human Insulin Inhibits the Mosquito NF-κB-Dependent Immune Response to Plasmodium falciparum

(2012) Nazzy Pakpour et al.   INFECTION AND IMMUNITY

Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53

(2012) Eleonora Napoli et al.   PLoS One

Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis

(2011) Pablo J Fernandez-Marcos et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Targeting Mitochondrial Dysfunction: Role for PINK1 and Parkin in Mitochondrial Quality Control

(2011) Derek P. Narendra et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling

(2011) Jisun Lee et al.   BIOCHEMICAL JOURNAL

Mitochondria and autophagy: Critical interplay between the two homeostats

(2011) Koji Okamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity

(2011) Jenni Durieux et al.   CELL

Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog

(2011) Michael Rera et al.   Cell Metabolism

The origin of intestinal stem cells in Drosophila

(2011) Craig A. Micchelli   DEVELOPMENTAL DYNAMICS

Energy metabolism affects susceptibility of Anopheles gambiae mosquitoes to Plasmodium infection

(2011) Jose Henrique M. Oliveira et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

Class B Scavenger Receptor Types I and II and CD36 Mediate Bacterial Recognition and Proinflammatory Signaling Induced by Escherichia coli, Lipopolysaccharide, and Cytosolic Chaperonin 60

(2011) I. N. Baranova et al.   JOURNAL OF IMMUNOLOGY

Localization of two Na+- or K+-H+ antiporters, AgNHA1 and AgNHA2, in Anopheles gambiae larval Malpighian tubules and the functional expression of AgNHA2 in yeast

(2011) Minghui A. Xiang et al.   JOURNAL OF INSECT PHYSIOLOGY

Image-based genome-wide siRNA screen identifies selective autophagy factors

(2011) Anthony Orvedahl et al.   NATURE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease

(2011) Madeleine Diedrich et al.   Proteome Science

Autophagy in Stem Cell Maintenance and Differentiation

(2011) Alexandre Teixeira Vessoni et al.   STEM CELLS AND DEVELOPMENT

Enterocyte death and intestinal barrier maintenance in homeostasis and disease

(2011) Lars Vereecke et al.   TRENDS IN MOLECULAR MEDICINE

Autophagy in health and disease. 5. Mitophagy as a way of life

(2010) Roberta A. Gottlieb et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Nitration of specific tyrosines in FoF1 ATP synthase and activity loss in aging

(2010) Virginia Haynes et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Glycoxidative stress-induced mitophagy modulates mitochondrial fates

(2010) Mei-Chen Lo et al.   Annals of the New York Academy of Sciences

Reactive Oxygen Species-Dependent Cell Signaling Regulates the Mosquito Immune Response to Plasmodium falciparum

(2010) Win Surachetpong et al.   ANTIOXIDANTS & REDOX SIGNALING

Autophagy Signaling Through Reactive Oxygen Species

(2010) Ju Huang et al.   ANTIOXIDANTS & REDOX SIGNALING

Atg1-mediated myosin II activation regulates autophagosome formation during starvation-induced autophagy

(2010) Hong-Wen Tang et al.   EMBO JOURNAL

Parkin-mediated selective mitochondrial autophagy, mitophagy: Parkin purges damaged organelles from the vital mitochondrial network

(2010) Atsushi Tanaka   FEBS LETTERS

Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease

(2010) Cleva Villanueva et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial peroxiredoxins are critical for the maintenance of redox state and the survival of adult Drosophila

(2010) Svetlana N. Radyuk et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nitrosylation and nitration of mitochondrial complex I in Parkinson's disease

(2010) Shankar J. Chinta et al.   FREE RADICAL RESEARCH

Does autophagy take a front seat in lifespan extension?

(2010) Goran Petrovski et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

An age of fewer histones

(2010) Philipp Oberdoerffer   NATURE CELL BIOLOGY

Naturally Occurring Triggers that Induce Apoptosis-Like Programmed Cell Death in Plasmodium berghei Ookinetes

(2010) Medhat Ali et al.   PLoS One

Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM

(2010) H. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HSP60 immune system network

(2010) Francisco J. Quintana et al.   TRENDS IN IMMUNOLOGY

Activation of Akt Signaling Reduces the Prevalence and Intensity of Malaria Parasite Infection and Lifespan in Anopheles stephensi Mosquitoes

(2010) Vanessa Corby-Harris et al.   PLoS Pathogens

Nitration of tyrosine residues 368 and 345 in the β-subunit elicits FoF1-ATPase activity loss

(2009) Yasuko Fujisawa et al.   BIOCHEMICAL JOURNAL

Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity inDrosophila

(2009) Svetlana N. Radyuk et al.   BIOCHEMICAL JOURNAL

Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain

(2009) Jeffrey M. Copeland et al.   CURRENT BIOLOGY

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice

(2009) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

Autophagy genes protect against Salmonella typhimurium infection and mediate insulin signaling-regulated pathogen resistance

(2009) K. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

MAPK ERK Signaling Regulates the TGF-β1-Dependent Mosquito Response to Plasmodium falciparum

(2009) Win Surachetpong et al.   PLoS Pathogens

Pfs 16 pivotal role in Plasmodium falciparum gametocytogenesis: A potential antiplasmodial drug target

(2008) Antoine Berry et al.   EXPERIMENTAL PARASITOLOGY

Insulin regulates aging and oxidative stress in Anopheles stephensi

(2008) M.-A. Kang et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE

How to Live Long and Prosper: Autophagy, Mitochondria, and Aging

(2008) Wei-Lien Yen et al.   PHYSIOLOGY

Extracellular Superoxide Dismutase Protects Against Matrix Degradation of Heparan Sulfate in the Lung

(2007) Corrine R. Kliment et al.   ANTIOXIDANTS & REDOX SIGNALING

Low levels of mammalian TGF-β1 are protective against malaria parasite infection, a paradox clarified in the mosquito host

(2007) Shirley Luckhart et al.   EXPERIMENTAL PARASITOLOGY

The SNMP/CD36 gene family in Diptera, Hymenoptera and Coleoptera: Drosophila melanogaster, D. pseudoobscura, Anopheles gambiae, Aedes aegypti, Apis mellifera, and Tribolium castaneum

(2007) Zachary Nichols et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY