EGL-9 Controls C. elegans Host Defense Specificity through Prolyl Hydroxylation-Dependent and -Independent HIF-1 Pathways

Intestinal Macrophage/Epithelial Cell-Derived CCL11/Eotaxin-1 Mediates Eosinophil Recruitment and Function in Pediatric Ulcerative Colitis

(2014) R. Ahrens et al.   JOURNAL OF IMMUNOLOGY

Insulin/IGF-1 and Hypoxia Signaling Act in Concert to Regulate Iron Homeostasis in Caenorhabditis elegans

(2012) Daniel Ackerman et al.   PLoS Genetics

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage

(2011) Steven Joshua Romney et al.   PLoS Genetics

Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity

(2010) Seung-Jae Lee et al.   CURRENT BIOLOGY

Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury

(2010) Simon A. Hirota et al.   GASTROENTEROLOGY

Loss of Prolyl Hydroxylase-1 Protects Against Colitis Through Reduced Epithelial Cell Apoptosis and Increased Barrier Function

(2010) Murtaza M. Tambuwala et al.   GASTROENTEROLOGY

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Activation of Hypoxia Inducible Factor 1 Is a General Phenomenon in Infections with Human Pathogens

(2010) Nadine Werth et al.   PLoS One

Plant and Animal Sensors of Conserved Microbial Signatures

(2010) P. C. Ronald et al.   SCIENCE

Hypoxia signaling and resistance in C. elegans

(2010) Jo Anne Powell-Coffman   TRENDS IN ENDOCRINOLOGY AND METABOLISM

C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1-Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1

(2010) Zhiyong Shao et al.   PLoS Pathogens

Distinct Pathogenesis and Host Responses during Infection of C. elegans by P. aeruginosa and S. aureus

(2010) Javier E. Irazoqui et al.   PLoS Pathogens

Community-associated methicillin-resistant Staphylococcus aureus skin infections: advances toward identifying the key virulence factors

(2009) Tyler K Nygaard et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Two Distinct Roles for EGL-9 in the Regulation of HIF-1-Mediated Gene Expression in Caenorhabditis elegans

(2009) Z. Shao et al.   GENETICS

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts

(2009) David R. Mole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroimmune regulation of antimicrobial peptide expression by a noncanonical TGF-β signaling pathway in Caenorhabditis elegans epidermis

(2009) Olivier Zugasti et al.   NATURE IMMUNOLOGY

Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment

(2009) Ingrid Arijs et al.   PLoS One

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses

(2009) I. Amit et al.   SCIENCE

HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans

(2009) Di Chen et al.   PLoS Genetics

Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans

(2009) Audrey Bellier et al.   PLoS Pathogens

The DAF-2 insulin-like signaling pathway independently regulates aging and immunity inC. elegans

(2008) Eric A. Evans et al.   AGING CELL

HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak

(2008) J. C. Morote-Garcia et al.   BLOOD

Diagnostic mRNA Expression Patterns of Inflamed, Benign, and Malignant Colorectal Biopsy Specimen and their Correlation with Peripheral Blood Results

(2008) O. Galamb et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Hypoxia-Inducible Factor Augments Experimental Colitis Through an MIF–Dependent Inflammatory Signaling Cascade

(2008) Yatrik M. Shah et al.   GASTROENTEROLOGY

Hypoxia-Inducible Factor–Dependent Repression of Equilibrative Nucleoside Transporter 2 Attenuates Mucosal Inflammation During Intestinal Hypoxia

(2008) Julio C. Morote–Garcia et al.   GASTROENTEROLOGY

Pharmacologic Augmentation of Hypoxia‐Inducible Factor–1α with Mimosine Boosts the Bactericidal Capacity of Phagocytes

(2008) Annelies S. Zinkernagel et al.   JOURNAL OF INFECTIOUS DISEASES

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Role for  -catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions

(2008) J. E. Irazoqui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition

(2007) Andreas Robinson et al.   GASTROENTEROLOGY