A Cytoplasmic Tail Determinant in HIV-1 Vpu Mediates Targeting of Tetherin for Endosomal Degradation and Counteracts Interferon-Induced Restriction

Compensatory Changes in the Cytoplasmic Tail of gp41 Confer Resistance to Tetherin/BST-2 in a Pathogenic Nef-Deleted SIV

(2011) Ruth Serra-Moreno et al.   Cell Host & Microbe

UBAP1 Is a Component of an Endosome-Specific ESCRT-I Complex that Is Essential for MVB Sorting

(2011) Flavia Stefani et al.   CURRENT BIOLOGY

Human Immunodeficiency Virus Type 1 and Related Primate Lentiviruses Engage Clathrin through Gag-Pol or Gag

(2011) S. Popov et al.   JOURNAL OF VIROLOGY

Role of the Endocytic Pathway in the Counteraction of BST-2 by Human Lentiviral Pathogens

(2011) D. Lau et al.   JOURNAL OF VIROLOGY

Separable Determinants of Subcellular Localization and Interaction Account for the Inability of Group O HIV-1 Vpu To Counteract Tetherin

(2011) R. Vigan et al.   JOURNAL OF VIROLOGY

Modulation of HIV-1-host interaction: role of the Vpu accessory protein

(2011) Mathieu Dubé et al.   Retrovirology

Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and Counteraction

(2011) Anna Le Tortorec et al.   Viruses-Basel

HIV-1 Vpu Blocks Recycling and Biosynthetic Transport of the Intrinsic Immunity Factor CD317/Tetherin To Overcome the Virion Release Restriction

(2011) S. Schmidt et al.   mBio

The Fifth Adaptor Protein Complex

(2011) Jennifer Hirst et al.   PLOS BIOLOGY

SIV Nef Proteins Recruit the AP-2 Complex to Antagonize Tetherin and Facilitate Virion Release

(2011) Fengwen Zhang et al.   PLoS Pathogens

The ESCRT-0 Component HRS is Required for HIV-1 Vpu-Mediated BST-2/Tetherin Down-Regulation

(2011) Katy Janvier et al.   PLoS Pathogens

Rab7A Is Required for Efficient Production of Infectious HIV-1

(2011) Marina Caillet et al.   PLoS Pathogens

Clathrin Facilitates the Morphogenesis of Retrovirus Particles

(2011) Fengwen Zhang et al.   PLoS Pathogens

Structural Basis of HIV-1 Tethering to Membranes by the BST-2/Tetherin Ectodomain

(2010) Andreas Hinz et al.   Cell Host & Microbe

Immune Evasion and Counteraction of Restriction Factors by HIV-1 and Other Primate Lentiviruses

(2010) Frank Kirchhoff   Cell Host & Microbe

Antagonism of CD317 Restriction of Human Immunodeficiency Virus Type 1 (HIV-1) Particle Release and Depletion of CD317 Are Separable Activities of HIV-1 Vpu

(2010) C. Goffinet et al.   JOURNAL OF VIROLOGY

Identification of Amino Acids in the Human Tetherin Transmembrane Domain Responsible for HIV-1 Vpu Interaction and Susceptibility

(2010) T. Kobayashi et al.   JOURNAL OF VIROLOGY

CD317/Tetherin Is Enriched in the HIV-1 Envelope and Downregulated from the Plasma Membrane upon Virus Infection

(2010) A. Habermann et al.   JOURNAL OF VIROLOGY

Serine-Threonine Ubiquitination Mediates Downregulation of BST-2/Tetherin and Relief of Restricted Virion Release by HIV-1 Vpu

(2010) A. A. Tokarev et al.   JOURNAL OF VIROLOGY

Cell-Cell Spread of Human Immunodeficiency Virus Type 1 Overcomes Tetherin/BST-2-Mediated Restriction in T cells

(2010) C. Jolly et al.   JOURNAL OF VIROLOGY

Structural insight into the mechanisms of enveloped virus tethering by tetherin

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations

(2010) H. L. Schubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The RING-CH Ligase K5 Antagonizes Restriction of KSHV and HIV-1 Particle Release by Mediating Ubiquitin-Dependent Endosomal Degradation of Tetherin

(2010) Claire Pardieu et al.   PLoS Pathogens

Antagonism of Tetherin Restriction of HIV-1 Release by Vpu Involves Binding and Sequestration of the Restriction Factor in a Perinuclear Compartment

(2010) Mathieu Dubé et al.   PLoS Pathogens

Tetherin Restricts Productive HIV-1 Cell-to-Cell Transmission

(2010) Nicoletta Casartelli et al.   PLoS Pathogens

Tetherin Inhibits HIV-1 Release by Directly Tethering Virions to Cells

(2009) David Perez-Caballero et al.   CELL

Nef Proteins from Simian Immunodeficiency Viruses Are Tetherin Antagonists

(2009) Fengwen Zhang et al.   Cell Host & Microbe

HIV-1 Antagonism of CD317 Is Species Specific and Involves Vpu-Mediated Proteasomal Degradation of the Restriction Factor

(2009) Christine Goffinet et al.   Cell Host & Microbe

Tetherin-Driven Adaptation of Vpu and Nef Function and the Evolution of Pandemic and Nonpandemic HIV-1 Strains

(2009) Daniel Sauter et al.   Cell Host & Microbe

HIV-1 Accessory Protein Vpu Internalizes Cell-surface BST-2/Tetherin through Transmembrane Interactions Leading to Lysosomes

(2009) Yukie Iwabu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HM1.24 Is Internalized from Lipid Rafts by Clathrin-mediated Endocytosis through Interaction with α-Adaptin

(2009) Naoko Masuyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of Tetherin-Restricting Activity upon Human Immunodeficiency Virus Type 1 Particle Release Correlates with Localization of Vpu in the trans-Golgi Network

(2009) M. Dube et al.   JOURNAL OF VIROLOGY

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

Antagonism to and Intracellular Sequestration of Human Tetherin by the Human Immunodeficiency Virus Type 2 Envelope Glycoprotein

(2009) A. Le Tortorec et al.   JOURNAL OF VIROLOGY

Vpu enhances HIV-1 virus release in the absence of Bst-2 cell surface down-modulation and intracellular depletion

(2009) Eri Miyagi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 Vpu Neutralizes the Antiviral Factor Tetherin/BST-2 by Binding It and Directing Its Beta-TrCP2-Dependent Degradation

(2009) Bastien Mangeat et al.   PLoS Pathogens

Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking

(2009) Richard S. Mitchell et al.   PLoS Pathogens

Species-Specific Activity of SIV Nef and HIV-1 Vpu in Overcoming Restriction by Tetherin/BST2

(2009) Bin Jia et al.   PLoS Pathogens

The Interferon-Induced Protein BST-2 Restricts HIV-1 Release and Is Downregulated from the Cell Surface by the Viral Vpu Protein

(2008) Nanette Van Damme et al.   Cell Host & Microbe

GGA and Arf Proteins Modulate Retrovirus Assembly and Release

(2008) Anjali Joshi et al.   MOLECULAR CELL

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

Requirements of the membrane proximal tyrosine and dileucine-based sorting signals for efficient transport of the subtype C Vpu protein to the plasma membrane and in virus release

(2008) Autumn Ruiz et al.   VIROLOGY