Coordinated Destruction of Cellular Messages in Translation Complexes by the Gammaherpesvirus Host Shutoff Factor and the Mammalian Exonuclease Xrn1

Importin  -Mediated Nuclear Import of Cytoplasmic Poly(A) Binding Protein Occurs as a Direct Consequence of Cytoplasmic mRNA Depletion

(2011) G. R. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

Crystal structure of a KSHV–SOX–DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoff

(2011) Claire Bagnéris et al.   NUCLEIC ACIDS RESEARCH

Deep Sequencing Reveals Direct Targets of Gammaherpesvirus-Induced mRNA Decay and Suggests That Multiple Mechanisms Govern Cellular Transcript Escape

(2011) Karen Clyde et al.   PLoS One

Sindbis Virus Usurps the Cellular HuR Protein to Stabilize Its Transcripts and Promote Productive Infections in Mammalian and Mosquito Cells

(2010) Kevin J. Sokoloski et al.   Cell Host & Microbe

mRNA Degradation Plays a Significant Role in the Program of Gene Expression Regulated by Phosphatidylinositol 3-Kinase Signaling

(2010) J. R. Graham et al.   MOLECULAR AND CELLULAR BIOLOGY

Human Pat1b Connects Deadenylation with mRNA Decapping and Controls the Assembly of Processing Bodies

(2010) S. Ozgur et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear Import of Cytoplasmic Poly(A) Binding Protein Restricts Gene Expression via Hyperadenylation and Nuclear Retention of mRNA

(2010) G. R. Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

Multiple mRNA Decapping Enzymes in Mammalian Cells

(2010) Man-Gen Song et al.   MOLECULAR CELL

All things must pass: contrasts and commonalities in eukaryotic and bacterial mRNA decay

(2010) Joel G. Belasco   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism

(2010) R. Tomecki et al.   RNA

The N-Terminal Domain of the Arenavirus L Protein Is an RNA Endonuclease Essential in mRNA Transcription

(2010) Benjamin Morin et al.   PLoS Pathogens

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Crystal structure of the shutoff and exonuclease protein from the oncogenic Kaposi’s sarcoma-associated herpesvirus

(2009) Sue-Li Dahlroth et al.   FEBS Journal

The role of RNAi and microRNAs in animal virus replication and antiviral immunity

(2009) J. L. Umbach et al.   GENES & DEVELOPMENT

A Bridge Crosses the Active-Site Canyon of the Epstein–Barr Virus Nuclease with DNase and RNase Activities

(2009) Marlyse Buisson et al.   JOURNAL OF MOLECULAR BIOLOGY

Host Shutoff Is a Conserved Phenotype of Gammaherpesvirus Infection and Is Orchestrated Exclusively from the Cytoplasm

(2009) S. Covarrubias et al.   JOURNAL OF VIROLOGY

Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site

(2009) Puwei Yuan et al.   NATURE

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

(2009) Wataru Kamitani et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

(2009) Claudia Schneider et al.   NUCLEIC ACIDS RESEARCH

The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes

(2009) B. Taddeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant Herpesvirus-Induced Polyadenylation Correlates With Cellular Messenger RNA Destruction

(2009) Yeon J. Lee et al.   PLOS BIOLOGY

Concordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA

(2009) David G. Hendrickson et al.   PLOS BIOLOGY

A Highly Structured, Nuclease-Resistant, Noncoding RNA Produced by Flaviviruses Is Required for Pathogenicity

(2008) Gorben P. Pijlman et al.   Cell Host & Microbe

Studies of the 5' Exonuclease and Endonuclease Activities of CPSF-73 in Histone Pre-mRNA Processing

(2008) X.-c. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Endonucleolytic RNA cleavage by a eukaryotic exosome

(2008) Alice Lebreton et al.   NATURE

SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

(2008) Andrea B Eberle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities

(2008) Daneen Schaeffer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

(2008) E. Huntzinger et al.   RNA

Modulation of enteroviral proteinase cleavage of poly(A)-binding protein (PABP) by conformation and PABP-associated factors

(2008) Carlos I. Rivera et al.   VIROLOGY