AAV Exploits Subcellular Stress Associated with Inflammation, Endoplasmic Reticulum Expansion, and Misfolded Proteins in Models of Cystic Fibrosis

Mutagenesis of Adeno-Associated Virus Type 2 Capsid Protein VP1 Uncovers New Roles for Basic Amino Acids in Trafficking and Cell-Specific Transduction

(2010) J. S. Johnson et al.   JOURNAL OF VIROLOGY

ER-associated complexes (ERACs) containing aggregated cystic fibrosis transmembrane conductance regulator (CFTR) are degraded by autophagy

(2009) Lianwu Fu et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Airway Epithelial Inflammation-induced Endoplasmic Reticulum Ca2+Store Expansion Is Mediated by X-box Binding Protein-1

(2009) Mary E. B. Martino et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystic fibrosis

(2009) Brian P O'Sullivan et al.   LANCET

Generation of Novel AAV Variants by Directed Evolution for Improved CFTR Delivery to Human Ciliated Airway Epithelium

(2009) Wuping Li et al.   MOLECULAR THERAPY

Epigenetic activation of unintegrated HIV-1 genomes by gut-associated short chain fatty acids and its implications for HIV infection

(2009) B. Kantor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Depletion of β-COP reveals a role for COP-I in compartmentalization of secretory compartments and in biosynthetic transport of caveolin-1

(2008) Melanie L. Styers et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Activation of the Unfolded Protein Response by ΔF508 CFTR

(2008) Rafal Bartoszewski et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Endoplasmic Reticulum Stress in Disease Pathogenesis

(2008) Jonathan H. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Endoplasmic reticulum stress in the absence of calnexin

(2008) Helen Coe et al.   CELL STRESS & CHAPERONES

Enhancement of Adeno-Associated Virus Infection by Mobilizing Capsids into and Out of the Nucleolus

(2008) J. S. Johnson et al.   JOURNAL OF VIROLOGY

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE