Identification of a Mutant PfCRT-Mediated Chloroquine Tolerance Phenotype in Plasmodium falciparum

Plant homologs of the Plasmodium falciparum chloroquine-resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses

(2010) S. C. Maughan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low efficacy of chloroquine: Time to switchover to artemisinin-based combination therapy for falciparum malaria in India

(2009) N. Valecha et al.   ACTA TROPICA

Disruption of aPlasmodium falciparumMultidrug Resistance-associated Protein (PfMRP) Alters Its Fitness and Transport of Antimalarial Drugs and Glutathione

(2009) Dipak Kumar Raj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Catalytic Roles forPlasmodium falciparumAminopeptidase P in the Food Vacuole and Cytosol

(2009) Daniel Ragheb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Decreasing Efficacy of Antimalarial Combination Therapy in Uganda Is Explained by Decreasing Host Immunity Rather than Increasing Drug Resistance

(2009) Bryan Greenhouse et al.   JOURNAL OF INFECTIOUS DISEASES

In Vivo Selection ofPlasmodium falciparumParasites Carrying the Chloroquine-SusceptiblepfcrtK76 Allele after Treatment with Artemether-Lumefantrine in Africa

(2009) Christin Sisowath et al.   JOURNAL OF INFECTIOUS DISEASES

A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria

(2009) Stéphane Picot et al.   MALARIA JOURNAL

Geographic patterns ofPlasmodium falciparumdrug resistance distinguished by differential responses to amodiaquine and chloroquine

(2009) Juliana Martha Sá et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chloroquine Transport via the Malaria Parasite's Chloroquine Resistance Transporter

(2009) R. E. Martin et al.   SCIENCE

Chloroquine Resistance-Conferring Mutations in pfcrt Give Rise to a Chloroquine-Associated H+ Leak from the Malaria Parasite's Digestive Vacuole

(2008) A. M. Lehane et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discordant Patterns of Genetic Variation at Two Chloroquine Resistance Loci in Worldwide Populations of the Malaria Parasite Plasmodium falciparum

(2008) R. K. Mehlotra et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Baseline in vitro efficacy of ACT component drugs on Plasmodium falciparum clinical isolates from Mali

(2008) Halima Kaddouri et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes

(2008) Eric H. Ekland et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Antimalarial drug use in general populations of tropical Africa

(2008) Florence Gardella et al.   MALARIA JOURNAL

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE