Letter
Immunology
Ayman Ahmed, Patricia Pignatelli, Arwa Elaagip, Muzamil M. Abdel Hamid, Omnia Fateh Alrahman, David Weetman
Summary: Research has identified the emergence of Anopheles stephensi mosquitoes in eastern Sudan, suggesting potential distinct invasions from neighboring countries.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Immunology
Vincent Pommier de Santi, Bouh Abdi Khaireh, Thomas Chiniard, Bruno Pradines, Nicolas Taudon, Sebastien Larreche, Abdoulraouf Bourhan Mohamed, Franck de Laval, Franck Berger, Florian Gala, Madjid Mokrane, Nicolas Benoit, Lionel Malan, Abdoulilah Ahmed Abdi, Sebastien Briolant
Summary: Anopheles stephensi mosquitoes in Djibouti are potentially causing a rise in malaria incidence by sharing breeding sites with Aedes aegypti and Culex quinquefasciatus. Additionally, there is documented resistance of Plasmodium falciparum to dihydroartemisinin/piperaquine in this country.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Parasitology
Catherine E. Oke, Sarah E. Reece, Petra Schneider
Summary: This study developed a non-destructive assay to quantify sporozoites of two rodent malaria species from sugar-soaked feeding substrates. However, the detection rate of expelled sporozoites was low, likely due to the variable and infrequent nature of sporozoite expulsion. Further investigations into the biological causes underlying the low detection rate are needed.
PARASITES & VECTORS
(2023)
Article
Immunology
Alia Zayed, Manal Moustafa, Reham Tageldin, James F. Harwood
Summary: This study discusses the impact of seasonal meteorologic variations and rainfall events on Anopheles stephensi mosquito populations at a US military base in Djibouti. Targeting surveillance and risk mitigation efforts for An. stephensi mosquitoes during optimal climatic conditions can contribute to malaria prevention and control in eastern Africa.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Multidisciplinary Sciences
Charles Whittaker, Arran Hamlet, Ellie Sherrard-Smith, Peter Winskill, Gina Cuomo-Dannenburg, Patrick G. T. Walker, Marianne Sinka, Samuel Pironon, Ashwani Kumar, Azra Ghani, Samir Bhatt, Thomas S. Churcher
Summary: The invasion of the malaria vector Anopheles stephensi in the Horn of Africa poses a threat to malaria control efforts across the continent. This study finds that the seasonal dynamics of An. stephensi are not well predicted by rainfall patterns, but are associated with temperature and land use. Timing entomological surveys to coincide with rainy periods is unlikely to improve the detection of An. stephensi, and indoor residual spraying campaigns during peak rainfall offer little improvement in reducing disease burden.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Microbiology
Kathrin Witmer, Farah A. Dahalan, Michael J. Delves, Sabrina Yahiya, Oliver J. Watson, Ursula Straschil, Darunee Chiwcharoen, Boodtee Sornboon, Sasithon Pukrittayakamee, Richard D. Pearson, Virginia M. Howick, Mara K. N. Lawniczak, Nicholas J. White, Arjen M. Dondorp, Lucy C. Okell, Kesinee Chotivanich, Andrea Ruecker, Jake Baum
Summary: Resistance to artemisinin-based combination therapy (ACT) in the Plasmodium falciparum parasite threatens recent progress in reducing global malaria deaths. Under artemisinin drug pressure, resistant parasites have a selective advantage in transmission, potentially leading to the spread of multidrug-resistant malaria beyond Southeast Asia.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
(2021)
Article
Immunology
Nora Cespedes, Erinn L. Donnelly, Casey Lowder, Gretchen Hansten, Delaney Wagers, Anna M. Briggs, Joseph Schauer, Lori Haapanen, Magnus Abrink, Judy Van de Water, Shirley Luckhart
Summary: Increased mast cells and MC mediators have been observed in malaria-related bacteremia, but their role in malarial immunity is not well understood. Through studying Mcpt4 in malaria-induced bacteremia, it was found that Mcpt4 knockout mice had significantly lower parasitemia but increased intestinal permeability and altered ileal adherens junction E-cadherin. Additionally, differences in immune response were observed between Mcpt4(-/-) and Mcpt4(+/+) mice, suggesting a role for Mcpt4 in host immune response modulation during malaria infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Multidisciplinary Sciences
Kelsey M. Sumner, Elizabeth Freedman, Lucy Abel, Andrew Obala, Brian W. Pence, Amy Wesolowski, Steven R. Meshnick, Wendy Prudhomme-O'Meara, Steve M. Taylor
Summary: The study conducted a longitudinal cohort study in a high transmission area in Western Kenya for 14 months, and found that asymptomatic malaria infections more than double the odds of transmission to a mosquito compared to symptomatic infections. Asymptomatic infections are the major contributor to mosquito infections in high transmission areas and could be targeted to reduce transmission.
NATURE COMMUNICATIONS
(2021)
Article
Parasitology
Pilate N. Kwi, Elvis E. Ewane, Marcel N. Moyeh, Livinus N. Tangi, Vincent N. Ntui, Francis Zeukeng, Denis D. Sofeu-Feugaing, Eric A. Achidi, Fidelis Cho-Ngwa, Alfred Amambua-Ngwa, Jude D. Bigoga, Tobias O. Apinjoh
Summary: The vectorial diversity, dynamics, and infectivity of mosquitoes in the slopes of Mount Cameroon vary across different seasons and altitudes, which has implications for malaria transmission and control.
PARASITES & VECTORS
(2022)
Article
Parasitology
Hossein Dehghan, Seyed Hassan Mosa-Kazemi, Bagher Yakhchali, Naseh Maleki-Ravasan, Hassan Vatandoost, Mohammad Ali Oshaghi
Summary: The wild-type and genetically modified strains of Enterobacter cloacae were found to significantly disrupt the development of Plasmodium berghei in the midgut of Anopheles stephensi mosquitoes. This suggests that these bacteria have the potential to provide a barrier or release effector molecules to combat malaria infection.
PARASITES & VECTORS
(2022)
Article
Multidisciplinary Sciences
Priscille Barreaux, Hilary Ranson, Geraldine M. M. Foster, Philip J. J. McCall
Summary: The blood feeding behavior of female mosquitoes, which affects their ability to transmit malaria, is not well understood in the presence of insecticide-treated nets (ITNs). This study examines how both insecticide resistant and susceptible mosquitoes interact with different types of nets while attempting to blood feed on a human arm. The results showed that ITNs did not effectively prevent host searching but significantly reduced blood feeding success and volume for all mosquitoes, although the resistant mosquitoes were able to compensate for the decrease by accelerating their rate of blood ingestion.
SCIENTIFIC REPORTS
(2023)
Article
Parasitology
Ayman Ahmed, Rua Khogali, Mohammed-Ahmed B. Elnour, Ryo Nakao, Bashir Salim
Summary: The Asian invasive malaria vector Anopheles stephensi has been confirmed in Khartoum, Sudan. A national entomological survey is urgently recommended to determine its distribution and susceptibility to malaria control measures.
PARASITES & VECTORS
(2021)
Article
Medicine, General & Internal
Arran Hamlet, Dereje Dengela, J. Eric Tongren, Fitsum G. Tadesse, Teun Bousema, Marianne Sinka, Aklilu Seyoum, Seth R. Irish, Jennifer S. Armistead, Thomas Churcher
Summary: Sub-Saharan Africa has experienced a reduction in malaria cases and deaths in recent years, but this progress may be at risk due to the invasion of Anopheles stephensi. A modeling study found that without additional interventions, malaria cases could increase by 50%. Scaling up vector control interventions would be necessary to prevent a major public health emergency, but it would come with significant costs.
Article
Infectious Diseases
Himmat Singh, Sanjeev Kumar Gupta, Kumar Vikram, Rekha Saxena, Amit Sharma
Summary: By providing proper metal lids or replacing damaged lids on underground water storage tanks as an environmental management approach, the breeding of the malaria vector, Anopheles stephensi, was successfully prevented in a desert village in western Rajasthan, leading to a significant reduction in mosquito density and improved community awareness and involvement.
Article
Remote Sensing
Fahimeh Youssefi, Mohammad Javad Valadan Zoej, Ahmad Ali Hanafi-Bojd, Alireza Borahani Dariane, Mehdi Khaki, Alireza Safdarinezhad
Summary: This study identifies high-risk depressions with the potential for Anopheles larval habitats by fusing remote sensing data with land-use and soil type maps, and creates a high-risk map of malaria based on these habitats.
INTERNATIONAL JOURNAL OF APPLIED EARTH OBSERVATION AND GEOINFORMATION
(2022)
