Two HIV-1 Variants Resistant to Small Molecule CCR5 Inhibitors Differ in How They Use CCR5 for Entry

Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors

(2012) Paul J Peters et al.   Retrovirology

Binding Thermodynamics of the N-Terminal Peptide of the CCR5 Coreceptor to HIV-1 Envelope Glycoprotein gp120†

(2009) Evan T. Brower et al.   BIOCHEMISTRY

Characterization of a Human Immunodeficiency Virus Type 1 V3 Deletion Mutation That Confers Resistance to CCR5 Inhibitors and the Ability To Use Aplaviroc-Bound Receptor

(2009) K. M. Nolan et al.   JOURNAL OF VIROLOGY

Quantitative Deep Sequencing Reveals Dynamic HIV-1 Escape and Large Population Shifts during CCR5 Antagonist Therapy In Vivo

(2009) Athe M. N. Tsibris et al.   PLoS One

Resistance to CCR5 inhibitors caused by sequence changes in the fusion peptide of HIV-1 gp41

(2009) C. G. Anastassopoulou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Virologic Failure in Therapy-Naive Subjects on Aplaviroc plus Lopinavir-Ritonavir: Detection of Aplaviroc Resistance Requires Clonal Analysis of Envelope

(2008) K. M. Kitrinos et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo Emergence of Vicriviroc Resistance in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Subject

(2008) A. M. N. Tsibris et al.   JOURNAL OF VIROLOGY

An Alteration of Human Immunodeficiency Virus gp41 Leads to Reduced CCR5 Dependence and CD4 Independence

(2008) B. M. Taylor et al.   JOURNAL OF VIROLOGY

Evolution Rescues Folding of Human Immunodeficiency Virus-1 Envelope Glycoprotein GP120 Lacking a Conserved Disulfide Bond

(2008) Rogier W. Sanders et al.   MOLECULAR BIOLOGY OF THE CELL

Mapping resistance to the CCR5 co-receptor antagonist vicriviroc using heterologous chimeric HIV-1 envelope genes reveals key determinants in the C2-V5 domain of gp120

(2008) Robert A. Ogert et al.   VIROLOGY

Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors

(2008) Pavel Pugach et al.   VIROLOGY

Neutralizing activity of antibodies to the V3 loop region of HIV-1 gp120 relative to their epitope fine specificity

(2008) Ralph Pantophlet et al.   VIROLOGY

Targeting Chemokine Receptors in HIV: A Status Report

(2007) Shawn E. Kuhmann et al.   Annual Review of Pharmacology and Toxicology

Structure of Antibody F425-B4e8 in Complex with a V3 Peptide Reveals a New Binding Mode for HIV-1 Neutralization

(2007) Christian H. Bell et al.   JOURNAL OF MOLECULAR BIOLOGY