Article
Parasitology
Gustavo Lazari Cacini, Jader de Oliveira, Tiago Belintani, Eder dos Santos Souza, Nicoly Olaia, Mara Cristina Pinto, Joao Aristeu da Rosa
Summary: This study utilized microscopy, morphometrics, and geometric morphometrics to measure and describe the morphological characters of the five nymphal instars of Rhodnius marabaensis, R. prolixus, and R. robustus. The research successfully characterized all five nymphal instars and distinguished the three species in each instar. The morphological and geometric morphometrics studies enabled the specific distinction of these three species in all five instars.
PARASITES & VECTORS
(2022)
Article
Immunology
Yanna Reis Praca, Paula Beatriz Santiago, Sebastien Charneau, Samuel Coelho Mandacaru, Izabela Marques Dourado Bastos, Kaio Luis da Silva Bentes, Sofia Marcelino Martins Silva, Waldeyr Mendes Cordeiro da Silva, Ionizete Garcia da Silva, Marcelo Valle de Sousa, Celia Maria de Almeida Soares, Jose Marcos Chaves Ribeiro, Jaime Martins Santana, Carla Nunes de Araujo
Summary: This study reports the first sialome study on the synanthropic triatomine Triatoma sordida, analyzing the transcript and protein compositions of its salivary glands. The results provide comprehensive information on the abundant protein families and enzyme classes, as well as the identification of specific proteins. This enhances the understanding of the vector's biology, hematophagous behavior, and subfamily's evolution.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Infectious Diseases
Heloisa Pinotti, Kaio Cesar Chaboli Alevi, Jader de Oliveira, Amanda Ravazi, Fernanda Fernandez Madeira, Yago Visinho dos Reis, Ana Beatriz Bortolozo de Oliveira, Maria Tercilia Vilela de Azeredo-Oliveira, Joao Aristeu da Rosa
Summary: The subfamily Triatominae consists of 156 species divided into five tribes, all potential vectors of Chagas disease. The Triatoma brasiliensis complex, with eight taxa, has been studied through experimental crosses to analyze the segregation pattern of phenotypic characteristics in hybrids. The results show the importance of integrative taxonomy in correctly identifying Chagas disease vectors, particularly in cases of natural hybridization.
INFECTION GENETICS AND EVOLUTION
(2021)
Article
Parasitology
Natalia Regina Cesaretto, Jader de Oliveira, Amanda Ravazi, Fernanda Fernandez Madeira, Yago Visinho dos Reis, Ana Beatriz Bortolozo de Oliveira, Roberto Dezan Vicente, Daniel Cesaretto Cristal, Cleber Galvao, Maria Tercilia Vilela de Azeredo-Oliveira, Joao Aristeu da Rosa, Kaio Cesar Chaboli Alevi
Summary: The taxonomy history of Meccus genus has been complex, but experimental crosses show reproductive compatibility among species of the T. phyllosoma complex, supporting the reorganization of Meccus in Triatoma genus.
PARASITES & VECTORS
(2021)
Article
Immunology
Manuel Medina, Sara Zuluaga, Maria Fernanda Martinez, Juan Carlos Bermudez, Carolina Hernandez, Virgilio Beltran, Natalia Velasquez-Ortiz, Marina Munoz, Juan David Ramirez, Omar Triana, Omar Cantillo-Barraza
Summary: The study evaluated the long-term success of a Chagas disease vector control campaign in the Tenza Valley region of Boyaca, Colombia. The findings suggest that Triatoma venosa has ecological and epidemiological characteristics to maintain the transmission of T. cruzi. This species has reinfested intervened households and plays an active role in domestic and peridomestic transmission, highlighting its epidemiological relevance for vector control strategies. The study also emphasizes the importance of conducting human serological studies for understanding the risks they face.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Parasitology
L. Abrahan, M. J. Cavallo, I. Amelotti
Summary: By involving householders in entomological evaluation, the study found that costs related to visited, evaluated, and sprayed domiciliary units were lower with community participation. Additionally, a larger number of domiciliary units were evaluated with community participation, leading to a more efficient and cost-effective control strategy for Chagas disease.
PARASITES & VECTORS
(2021)
Article
Biochemistry & Molecular Biology
Sandra Lopez, Alejandro Tapia, Julio Zygadlo, Raul Stariolo, Gustavo A. Abraham, Pablo R. Cortez Tornello
Summary: The study investigates the potential repellent activity of Zuccagnia punctata essential oil (ZEO) and poly(epsilon-caprolactone) matrices loaded with ZEO (ZEOP) against Triatoma infestans and other blood-sucking insects. The results show that both ZEO and ZEOP exhibit significant repellent activity, with ZEO demonstrating strong repellency against T. infestans within 72 hours.
Article
Entomology
Jose Alejandro Martinez-Ibarra, Maria Elena Villagran-Herrera, Jose Antonio de Diego-Cabrera, J. Guadalupe Michel-Parra
Summary: This study examined reproductive isolation, fertility, and the segregation of morphological characteristics in Triatoma mexicana Herrich-Schaeffer populations from Mexico. High percentages of couples with (fertile) offspring were observed in crosses between populations from Penamiller, Meztitlan, and Orizabita. However, crosses involving Tierra Blanca showed low fertility, especially with Meztitlan. Morphologically, the F1 generation individuals from Tierra Blanca resembled individuals from other locations, while F1 individuals from Penamiller looked like Penamiller. Crosses between F1 and F1 progeny indicated Mendelian dominant/recessive relationships for certain morphological traits. The results suggest that Penamiller, Meztitlan, and Orizabita populations are not reproductively isolated, while Tierra Blanca is undergoing speciation through allopatry.
JOURNAL OF MEDICAL ENTOMOLOGY
(2023)
Article
Entomology
Benjamin Nogueda-Torres, Oziel D. Montanez-Valdez, J. G. Michel-Parra, Diana M. Martinez-Grant, J. Alejandro Martinez-Ibarra
Summary: The study evaluated the vector characteristics of three populations of Triatoma dimidiata sensu stricto in western Mexico, finding that these populations are potentially efficient vectors of Trypanosoma cruzi and could contribute to the high prevalence of infection in human populations in the region.
JOURNAL OF MEDICAL ENTOMOLOGY
(2021)
Article
Public, Environmental & Occupational Health
Maria Cristina Oliveira Azevedo Campos, Thainara da Silva Goncalves, Renata Luiz Ursine, Sandra da Silva Barros Marinho, Angel Rodriguez Moreno, Lileia Goncalves Diotaiuti, Renata Fiuza Damasceno, Ariela Ferreira Mota, Antonio Luiz Pinho Ribeiro, Ester Cerdeira Sabino, Thallyta Maria Vieira
Summary: The study evaluated the occurrence, natural infection, and spatial distribution of triatomines in the urban area of Montes Claros, a municipality endemic to Chagas disease in the north of Minas Gerais, Brazil. The Chagas disease control program in this area is disjointed, and the diversity of infected triatomines in residential units raises concerns about potential transmission risks to domestic animals and humans.
ZOONOSES AND PUBLIC HEALTH
(2022)
Article
Zoology
Raissa N. Brito, Rita C. M. Souza, Lileia Diotaitui, Valeria S. Lima, Raquel A. Ferreira
Summary: The Colecao de Vetores de Tripanosomatideos (Fiocruz/COLVET) in Minas Gerais, Brazil, is a significant collection of blood-sucking triatomines vectors of Trypanosoma cruzi, with 12,568 specimens from 77 species and 11 genera. The collection aims to support scientific research, educational activities, and entomological surveillance, providing valuable services in these areas and to public health.
Article
Parasitology
Vinicius Fernandes de Paiva, Joao Aristeu da Rosa, Walter Ceretti Junior, Mauro Toledo Marrelli, Jader de Oliveira
Summary: This study confirms the presence of Psammolestes tertius in the state of Parana, Brazil, adding to the diversity of triatomines in the region. The findings suggest that the biodiversity of these insects may have been underestimated.
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
(2021)
Review
Endocrinology & Metabolism
Yu Feng Shang, Yi Yang Shen, Meng Chen Zhang, Min Chao Lv, Tong Ying Wang, Xue Qun Chen, Jun Lin
Summary: Saliva production and secretion are essential functions of the salivary glands, with multiple functions including moistening, digestion, mineralization, lubrication, and mucosal protection. Saliva undergoes dynamic changes in its chemical and physical properties during physiological and pathophysiological processes. The central nervous system regulates salivary secretion and function through various neurotransmitters and neuroreceptors. Salivary glands play a crucial role in innate and adaptive immunity and protection, and saliva contains potential biomarkers for monitoring and predicting health and disease in clinical practice and precision medicine.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Entomology
Ricardo Alejandre-Aguilar, Alberto Antonio-Campos, Julio Noguez-Garcia, Nancy Rivas
Summary: This study found that the T. pallidipennis population in Tecozautla, Mexico has the ability to reproduce and infest human dwellings two years after settling down, posing a potential risk to the local population.
JOURNAL OF VECTOR ECOLOGY
(2023)
Article
Parasitology
Rubens Antonio da Silva, Vera Aparecida Oliveira Estevao, Agnaldo Nepomuceno Duarte, Priscilla Cipolini Maria
Summary: This communication reports on the occurrence of colonization by Panstrongylus megistus in an urban park in Sao Paulo, Brazil, indicating evidence of its potential to occupy artificial ecotopes and pose a risk to the human population.
REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL
(2021)
Review
Microbiology
Jessyca Freitas-Silva, Bruno Francesco Rodrigues de Oliveira, Gabriel Rodrigues Dias, Marianna Machado de Carvalho, Marinella Silva Laport
Summary: Marine sponge-associated bacteria are well-known producers of bioactive compounds, but little progress has been made in the investigation of biosurfactants produced by these bacteria. This review compiles the current knowledge on biosurfactants from sponge-associated bacteria, with a focus on their biotechnological applications. Lipopeptides and glycolipids were found to be the most identified chemical classes of biosurfactants.
CRITICAL REVIEWS IN MICROBIOLOGY
(2023)
Article
Physiology
Vanessa S. T. Rodrigues, Egberto G. Moura, Thamara C. Peixoto, Patricia N. Soares, Bruna P. Lopes, Iala M. Bertasso, Beatriz S. Silva, S. S. Cabral, G. E. G. Kluck, G. C. Atella, P. L. Trindade, J. B. Daleprane, Elaine Oliveira, Patricia Cristina Lisboa
Summary: The gut microbiota affects the host's metabolic phenotype, impacting health and disease. The gut-brain axis connects the intestine with the centers of hunger and satiety, affecting eating behavior. Overfeeding during lactation changes the gut-brain axis, leading to hyperphagia and obesity in the offspring.
PHYSIOLOGICAL REPORTS
(2022)
Review
Fisheries
Anna Luiza Bauer Cancellas, Welling Felipe Costa, Jessyca Freitas-Silva, Isabelle Rodrigues Lopes, Bruno Francesco Rodrigues de Oliveira, Marinella Silva Laport
Summary: Aquaculture is a crucial food industry worldwide, but its growth is threatened by microbial infections and climate change. To ensure food security, new omics technologies, such as genomics, need to be applied to assess microbial communities and study antimicrobial resistance.
Article
Biochemistry & Molecular Biology
Bruno Francesco Rodrigues de Oliveira, Jessyca Freitas-Silva, Anna Luiza Bauer Canellas, Wellington Felipe Costa, Marinella Silva Laport
Summary: The partnership between sponges and microorganisms is considered a successful symbiotic association with potential biotechnological applications. However, there are several understudied or ignored areas in sponge microbial biotechnology. This perspective aims to highlight these underrated facets and propose further research in the field. The study showcases the valuable biomolecules produced by sponge microbiome members and their potential applications in various sectors.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY
(2023)
Article
Ecology
Barbara Ribeiro, Andre Padua, Bruno Francesco Rodrigues de Oliveira, Gabriela Puccinelli, Flavio da Costa Fernandes, Marinella Silva Laport, Michelle Klautau
Summary: This study is the first in situ characterization of the microbiota of exotic calcareous sponges. The results show that the microbiota of Sycettusahastifera is more stable compared to that of Paraleucillamagna. Additionally, each sponge species harbored a dominant proteobacterial OTU potentially active in the nitrogen cycle, which could contribute to sponge detoxification.
Review
Microbiology
Anna Luiza Bauer Canellas, Marinella Silva Laport
Summary: The genus Aeromonas is a group of Gram-negative bacilli widely distributed in aquatic habitats, and can also be found in terrestrial environments and in close association with humans and animals. They are versatile bacteria with high genomic plasticity and the ability to adapt to different environments and extreme conditions. Recent advances in whole-genome sequencing have revealed the potential of Aeromonas spp. for the discovery of novel industrial biocatalysts, bioremediation strategies, and biopolyester production.
CRITICAL REVIEWS IN MICROBIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Karina do Carmo de Vasconcelos Girardi, Bruno Siqueira Mietto, Karoline dos Anjos Lima, Georgia Correa Atella, Debora Santos da Silva, Antonio Marcos Rodrigues Pereira, Patricia Sammarco Rosa, Flavio Alves Lara
Summary: This study found that the leprosy bacteria and PGL-1 induce a toxic Schwann cell phenotype by modifying host lipid metabolism, resulting in profound implications for neuronal loss. The inhibition of Akt pathway is effective in preventing this damage.
JOURNAL OF NEUROCHEMISTRY
(2023)
Article
Infectious Diseases
Anna Luiza Bauer Canellas, Bruno Francesco Rodrigues de Oliveira, Marinella Silva Laport
Summary: Antimicrobial resistance (AMR) is a global challenge that hinders the treatment of various infections. In order to address this issue, a holistic approach beyond clinical settings is necessary. We investigated antimicrobial-resistant Aeromonas strains from an urban estuary in Brazil and found that most strains carried resistance genes for both antimicrobial drugs and heavy metals. A particular strain also carried the bla(KPC) gene, which codes for a carbapenemase. Our findings highlight the importance of considering the versatility and pathogenicity of A. hydrophila in the context of One Health.
Article
Microbiology
Wellington Felipe Costa, Rodolfo Paranhos, Marianne Pataro Mello, Renata Cristina Picao, Marinella Silva Laport
Summary: Bacterial resistance to antimicrobials is a global problem, and its occurrence in aquatic environments, such as tropical estuaries, might be associated with anthropogenic pollution. In this study, the occurrence of antimicrobial-resistant Escherichia coli was investigated in Guanabara Bay, Brazil, and it was found that ESBL-producing E. coli strains were frequently detected in the most polluted areas. These strains carried ESBL genes, with the bla(CTX-M) allele being the most predominant. The presence of ESBL-producing E. coli suggests a potential risk to human exposure and fish consumption.
ENVIRONMENTAL MICROBIOLOGY
(2023)
Article
Food Science & Technology
Jessika Geisebel Oliveira Neto, Juliana Woyames, Cherley Borba Vieira Andrade, Mariana Macedo de Almeida, Larissa Brito Fassarella, Georgia Correia Atella, Christina Maeda Takyia, Isis Hara Trevenzoli, Carmen Cabanelas Pazos-Moura
Summary: Perinatal maternal moderately high-fat diet (mHFD) leads to obesity and fatty liver disease in offspring, but maternal fish oil (FO) supplementation may reduce these disorders. This study examines the effects of FO given to pregnant rats on the offspring's liver at weaning. The results show that mHFD offspring have higher body mass, adiposity, hepatic damage, steatosis, inflammation, and damaged mitochondria. FO partially mitigates hepatic damage and modifies lipid metabolism and mitochondrial morphology.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Article
Cell Biology
Aline Donato-Trancoso, Regina V. de Carvalho Faria, Bianca C. de S. Ribeiro, Jeane S. S. Nogueira, Georgia C. Atella, Lin Chen, Bruna Romana-Souza
Summary: This study investigated the effects of a diet rich in extra virgin olive oil (EVOO) on acute wound healing. Short-term administration of EVOO increased oxidative damage and pro-inflammatory responses, impairing wound closure. Long-term administration, on the other hand, reduced oxidative damage and enhanced anti-inflammatory responses, improving wound closure.
WOUND REPAIR AND REGENERATION
(2023)
Article
Endocrinology & Metabolism
Camilla P. Dias-Rocha, Julia C. B. Costa, Yamara S. Oliveira, Larissa B. Fassarella, Juliana Woyames, Georgia C. Atella, Gustavo R. C. Santos, Henrique M. G. Pereira, Carmen C. Pazos-Moura, Mariana M. Almeida, Isis H. Trevenzoli
Summary: Maternal high-fat diet during gestation and lactation affects the endocannabinoid system in rat offspring, leading to obesity and preference for fat. However, contrary to expectations, the study found that the high-fat diet reduced the levels of endocannabinoids in breast milk. This reduction in endocannabinoid exposure during lactation may contribute to sex-dependent changes in brain signaling and the programming of preference for fat in adolescent male offspring.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Plant Sciences
Renato Crespo Pereira, Wladimir Costa Paradas, Rodrigo Tomazetto de Carvalho, Davyson de Lima Moreira, Alphonse Kelecom, Raoni Moreira Ferreira Passos, Georgia Correa Atella, Leonardo Tavares Salgado
Summary: The brown marine macroalga Padina gymnospora produces defensive chemicals and calcium carbonate on its surface as potential protections against herbivory. The chemical compounds extracted from P. gymnospora showed a significant reduction in consumption by the sea urchin Lytechinus variegatus, while the calcium carbonate did not provide physical protection. A specific hydrocarbon compound, 5Z,8Z,11Z,14Z-heneicosatetraene, exhibited a significant defensive property against the sea urchin.
Article
Chemistry, Multidisciplinary
Raquel Silva, Levy Domingos, Gabriellen de Castro, Marinella Laport, Antonio Ferreira-Pereira, Murilo Lima, Fernando Cotinguiba
Summary: A chemical investigation of Waltheria indica stem identified twelve 4-quinolone alkaloids, with waltheriones having chemosystematic significance in distinguishing Waltheria and Melochia genera. Waltherione G was found to reverse fluconazole-resistance in yeast, while isolated alkaloids showed promising activities in leishmanicidal and bactericidal tests.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Parasitology
Valter Viana Andrade-Neto, Pedro Paulo de Abreu Manso, Miria Gomes Pereira, Nuccia Nicole Theodoro de Cicco, Georgia Correa Atella, Marcelo Pelajo-Machado, Rubem Figueiredo Sadok Menna-Barreto, Eduardo Caio Torres-Santos
Summary: A significant amount of exogenous cholesterol is found in Leishmania promastigotes and amastigotes, and the absence of exogenous cholesterol enhances the replication of the parasite in infected macrophages. Understanding cholesterol transport can guide the development of new drugs for the treatment of leishmaniases.
MEMORIAS DO INSTITUTO OSWALDO CRUZ
(2022)