Article
Education & Educational Research
Volkmar P. Engerer
Summary: This study implements a dynamic research design for collaborative digital writing in higher education, focusing on text components, external variables, time management, and knowledge construction, with the addition of four time-related features. It demonstrates how the temporal organization of a CDW process can be visualized and how central concepts are dynamically related to each other.
EDUCATION AND INFORMATION TECHNOLOGIES
(2021)
Article
Computer Science, Information Systems
Mona Moradi, Mohammad Rahmanimanesh, Ali Shahzadi
Summary: This paper presents a density-based method for extracting topic descriptors from academic articles. The research priorities for four countries and the closeness of research in developing countries to developed countries are measured. The experimental results show that the proposed method outperforms baseline methods in terms of clustering precision, recall, and accuracy.
JOURNAL OF KING SAUD UNIVERSITY-COMPUTER AND INFORMATION SCIENCES
(2022)
Article
Public, Environmental & Occupational Health
Eric Tate, Valerie Decker, Craig Just
Summary: Interdisciplinary research is crucial in flood resilience studies, emphasizing team collaboration and systematic integration of disciplinary knowledge. Collaborative processes are deemed more important than scholarly outcomes for knowledge integration. Assessing team readiness and changes in proximity components are essential in enhancing knowledge integration potential.
Review
Microbiology
Melis N. Anahtar, Jason H. Yang, Sanjat Kanjilal
Summary: Machine learning in predicting antimicrobial resistance, understanding cellular functions disrupted by antibiotics, and antimicrobial stewardship has shown increasing potential and become a challenging phenomenon in modern medicine. Although still in its infancy, the continued growth of data and interest ensures that it will become an important tool for future translational research programs.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Review
Management
Mary Ryder, Elisabeth Jacob
Summary: The study aims to explore a proposed translational research continuum for nurse practitioners, highlighting the importance of integrating scientific processes for evidence-based practice and evaluation of outcomes. A translational research framework has the potential to strengthen nursing research in the nurse practitioner role, placing clinical nursing leaders in an equitable research position with all healthcare professionals. The continuum provides nursing management with a benchmark for nursing research and supports research engagement for nurse practitioners.
JOURNAL OF NURSING MANAGEMENT
(2022)
Article
Social Sciences, Interdisciplinary
Nestor Armando Nova, Rafael Andres Gonzalez
Summary: This study aims to identify dimensions and barriers to evaluating and leveraging collaboration in a large translational research ecosystem and develops a methodological design for evaluation. The empirical results show that collaboration is closely related to factors and barriers at the socio-technical, management, operational, and institutional levels and provide valuable insights for managing and improving collaborative efforts.
Article
Management
M. S. Reed, M. Ferre, J. Martin-Ortega, R. Blanche, R. Lawford-Rolfe, M. Dallimer, J. Holden
Summary: This study provides a new definition of research impact and impact evaluation, develops a typology of research impact evaluation designs, and proposes a methodological framework to guide evaluations of research impact. The subjective nature of impacts is recognized, leading to the identification of five types of impact evaluation design. Using the proposed guidance, researchers, funders, and stakeholders can select suitable evaluation designs and methods to evidence the impact of research from any discipline.
Article
Immunology
David M. Aanensen, Celia C. Carlos, Pilar Donado-Godoy, Iruka N. Okeke, K. L. Ravikumar
Summary: This Supplement details the practical implementation of whole-genome sequencing across laboratories in Colombia, India, Nigeria, and the Philippines as part of the National Institute for Health Research Global Health Research Unit on Genomic Surveillance of Antimicrobial Resistance project.
CLINICAL INFECTIOUS DISEASES
(2021)
Review
Health Care Sciences & Services
Shishi Wu, Elias Tannous, Victoria Haldane, Moriah E. Ellen, Xiaolin Wei
Summary: This article systematically reviews the implementation barriers and facilitators of behavior change interventions to promote rational antibiotic use in low- and middle-income countries (LMICs). The study found that the most common factors influencing implementation were related to the inner setting and external policy environment. Comprehensive efforts at the policy, organizational, and implementation levels are needed to facilitate the implementation of interventions to improve rational antibiotic use.
IMPLEMENTATION SCIENCE
(2022)
Article
Cell Biology
Xubin Zheng, Qiong Wu, Haonan Wu, Kwong-Sak Leung, Man-Hon Wong, Xueyan Liu, Lixin Cheng
Summary: This study introduced the most prevalent methods for processing bisulfite sequencing data and evaluated the consistency of the data acquired from different measurements in liver cancer. Differential methylated genes measured by various bisulfite sequencing assays and 450 k beadchip were consistently hypo-methylated in liver cancer with high functional similarity.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Review
Business
Naomi Haefner, Vinit Parida, Oliver Gassmann, Joakim Wincent
Summary: This study provides a systematic review and analysis of different approaches by companies to using AI, addressing the lack of frameworks to successfully implement and scale AI. The key components and phases of implementing and scaling AI in organizations are identified based on these experiences.
TECHNOLOGICAL FORECASTING AND SOCIAL CHANGE
(2023)
Article
Microbiology
Connie Lam, Jessica Johnson-Mackinnon, Kerri Basile, Winkie Fong, Carl J. E. Suster, Mailie Gall, Jessica Agius, Shona Chandra, Jenny Draper, Elena Martinez, Alexander Drew, Qinning Wang, Sharon C. Chen, Jen Kok, Dominic E. Dwyer, Vitali Sintchenko, Rebecca J. Rockett
Summary: This study presents a framework for optimizing sequencing efficiency in public health surveillance based on the ongoing evolution of the COVID-19 pandemic. It found that genome coverage decreased over time but could be recovered through primer pooling optimization or implementation of new primer sets. A minimum genome coverage was required to accurately cluster transmission events.
MICROBIOLOGY SPECTRUM
(2023)
Article
Genetics & Heredity
Jennifer L. Young, Meghan C. Halley, Beatriz Anguiano, Liliana Fernandez, Jonathan A. Bernstein, Matthew T. Wheeler, Holly K. Tabor, Undiagnosed Dis Network Consortium
Summary: This study examined the experiences of parents from diverse backgrounds with enrolling their children in clinical genomics research on rare diseases. The results suggest that variables beyond race/ethnicity may influence access in clinical genomics research. Therefore, future efforts should consider utilizing varied recruitment strategies to reach participants with diverse sociodemographic characteristics.
FRONTIERS IN GENETICS
(2022)
Review
Clinical Neurology
Toshiaki Onitsuka, Yoji Hirano, Kiyotaka Nemoto, Naoki Hashimoto, Itaru Kushima, Daisuke Koshiyama, Michihiko Koeda, Tsutomu Takahashi, Yoshihiro Noda, Junya Matsumoto, Kenichiro Miura, Takanobu Nakazawa, Takatoshi Hikida, Kiyoto Kasai, Norio Ozaki, Ryota Hashimoto
Summary: The underlying pathologies of psychiatric disorders are still unknown, causing significant personal and social losses. Conducting large-sample-size research and collaborative research across various fields can help clarify the core pathological mechanisms underlying psychiatric disorders and contribute to the development of young researchers.
PSYCHIATRY AND CLINICAL NEUROSCIENCES
(2022)
Article
Medicine, Research & Experimental
Meina Li, Bin Lian, Xiaoxiong Xu, Pan Zhao, Bihan Tang, Chaoqun Hu, Xiang Liu, Wenya Yu, Lulu Zhang
Summary: The study revealed that the majority of clinicians are willing to collaborate in translational medical research, with their willingness being influenced by factors such as current research type, role, burdens, preferred partners, and relationship independence. Clinicians should evaluate their time, role, burdens, personal preferences for research relationships, and appropriate partners before deciding to collaborate based on their current translational medical research and its goals.
JOURNAL OF TRANSLATIONAL MEDICINE
(2021)
Editorial Material
Genetics & Heredity
A. Cecile J. W. Janssens, James P. Evans
GENETICS IN MEDICINE
(2015)
Review
Genetics & Heredity
Nora B. Henrikson, Elizabeth M. Webber, Katrina A. Goddard, Aaron Scrol, Margaret Piper, Marc S. Williams, Doris T. Zallen, Ned Calonge, Theodore G. Ganiats, A. Cecile J. W. Janssens, Ann Zauber, Iris Lansdorp-Vogelaar, Marjolein van Ballegooijen, Evelyn P. Whitlock
GENETICS IN MEDICINE
(2015)
Editorial Material
Genetics & Heredity
A. Cecile J. W. Janssens
GENETICS IN MEDICINE
(2016)
Article
Genetics & Heredity
Rachel R. J. Kalf, Raluca Mihaescu, Suman Kundu, Peter de Knijff, Robert C. Green, A. Cecile J. W. Janssens
GENETICS IN MEDICINE
(2014)
Editorial Material
Genetics & Heredity
A. Cecile J. W. Janssens
GENETICS IN MEDICINE
(2015)
Article
Ethics
Eline M. Bunnik, A. Cecile J. W. Janssens, Maartje H. N. Schermer
JOURNAL OF MEDICAL ETHICS
(2015)
Article
Neurosciences
Vishnudutt Purohit, Rao S. Rapaka, Joni Rutter
JOURNAL OF NEUROIMMUNE PHARMACOLOGY
(2014)
Editorial Material
Genetics & Heredity
A. Cecile J. W. Janssens
Article
Health Care Sciences & Services
A. Cecile J. W. Janssens, Marta Gwinn, J. Elaine Brockman, Kimberley Powell, Michael Goodman
BMC MEDICAL RESEARCH METHODOLOGY
(2020)
Editorial Material
Biology
Cecile Janssens
Article
Oncology
Jeroen J. van den Broek, Clyde B. Schechter, Nicolien T. van Ravesteyn, A. Cecile J. W. Janssens, Michael C. Wolfson, Amy Trentham-Dietz, Jacques Simard, Douglas F. Easton, Jeanne S. Mandelblatt, Peter Kraft, Harry J. de Koning
Summary: Breast cancer family history and polygenic risk score can guide screening decisions for women aged 30-50 years. Combining family history and PRS has greater benefits in terms of life-years gained and breast cancer deaths averted compared to biennial screening from 50 to 74 years old.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE
(2021)
Article
Genetics & Heredity
Bart Penders, A. Cecile J. W. Janssens
Summary: Polygenic risk scores (PRS) are distinct from other biomarkers as they are calculated, compiled or constructed through the statistical assemblage of genetic variants. How researchers frame and name PRSs impacts how we interpret and value their results. Important questions include what PRS seeks to represent, whether current ways of 'doing PRS' are optimal and responsible, and the basis for the credibility of PRS-based knowledge claims.
Review
Medicine, Research & Experimental
Jessica M. Faupel-Badger, Amanda L. Vogel, Christopher P. Austin, Joni L. Rutter
Summary: This article offers considerations for developing new educational opportunities for a diverse and skilled translational science workforce based on decades of advances and experiential knowledge. It emphasizes the need for new education approaches that distill key concepts and practices in translational science from past and ongoing research initiatives. The National Center for Advancing Translational Sciences (NCATS) has developed guiding principles for translational science and is disseminating them through new education activities aiming to reach a broad scientific audience.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE
(2022)
