Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex
出版年份 2014 全文链接
标题
Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex
作者
关键词
-
出版物
PLoS Genetics
Volume 10, Issue 10, Pages e1004626
出版商
Public Library of Science (PLoS)
发表日期
2014-10-03
DOI
10.1371/journal.pgen.1004626
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1
- (2014) Hannah C. Dooley et al. MOLECULAR CELL
- UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs
- (2014) S. D. Pirooz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Beclin 2 Functions in Autophagy, Degradation of G Protein-Coupled Receptors, and Metabolism
- (2013) Congcong He et al. CELL
- PtdIns(3)P-bound UVRAG coordinates Golgi–ER retrograde and Atg9 transport by differential interactions with the ER tether and the beclin 1 complex
- (2013) Shanshan He et al. NATURE CELL BIOLOGY
- Phosphatidylinositol-3-phosphate regulates sorting and processing of amyloid precursor protein through the endosomal system
- (2013) Etienne Morel et al. Nature Communications
- Beclin1: A role in membrane dynamics and beyond
- (2012) Ellen Wirawan et al. Autophagy
- Genome-wide siRNA screen reveals amino acid starvation-induced autophagy requires SCOC and WAC
- (2012) Nicole C McKnight et al. EMBO JOURNAL
- Endotoxin Priming of Neutrophils Requires Endocytosis and NADPH Oxidase-dependent Endosomal Reactive Oxygen Species
- (2012) Fred S. Lamb et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Beclin-1-interacting autophagy protein Atg14L targets the SNARE-associated protein Snapin to coordinate endocytic trafficking
- (2012) H. J. Kim et al. JOURNAL OF CELL SCIENCE
- Disrupted Autophagy Leads to Dopaminergic Axon and Dendrite Degeneration and Promotes Presynaptic Accumulation of -Synuclein and LRRK2 in the Brain
- (2012) L. G. Friedman et al. JOURNAL OF NEUROSCIENCE
- Host Cell Autophagy Modulates Early Stages of Adenovirus Infections in Airway Epithelial Cells
- (2012) X. Zeng et al. JOURNAL OF VIROLOGY
- Macroautophagy deficiency mediates age-dependent neurodegeneration through a phospho-tau pathway
- (2012) Keiichi Inoue et al. Molecular Neurodegeneration
- Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
- (2012) N. Jaber et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG
- (2012) Xiaohua Li et al. Nature Communications
- The Atg6/Vps30/Beclin 1 ortholog BEC-1 mediates endocytic retrograde transport in addition to autophagy inC. elegans
- (2011) Alexander Ruck et al. Autophagy
- Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease
- (2011) Isabel Nascimento-Ferreira et al. BRAIN
- Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation
- (2010) Hannah E.J. Polson et al. Autophagy
- A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
- (2010) Sigrid B. Thoresen et al. EXPERIMENTAL CELL RESEARCH
- The Beclin 1–VPS34 complex – at the crossroads of autophagy and beyond
- (2010) Sarah F. Funderburk et al. TRENDS IN CELL BIOLOGY
- From a Global View to Focused Examination: Understanding Cellular Function of Lipid Kinase VPS34-Beclin 1 Complex in Autophagy
- (2010) Z. Yue et al. Journal of Molecular Cell Biology
- Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
- (2009) Anne Simonsen et al. JOURNAL OF CELL BIOLOGY
- Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in -Synuclein Models of Parkinson's and Lewy Body Diseases
- (2009) B. Spencer et al. JOURNAL OF NEUROSCIENCE
- Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex
- (2009) Yun Zhong et al. NATURE CELL BIOLOGY
- Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
- (2009) Kohichi Matsunaga et al. NATURE CELL BIOLOGY
- Rab GTPases as coordinators of vesicle traffic
- (2009) Harald Stenmark NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Autophagy in the Pathogenesis of Disease
- (2008) Beth Levine et al. CELL
- A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding
- (2008) Harold B J Jefferies et al. EMBO REPORTS
- Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease
- (2008) B. Ravikumar et al. JOURNAL OF CELL SCIENCE
- Autophagy fights disease through cellular self-digestion
- (2008) Noboru Mizushima et al. NATURE
- Beclin1-binding UVRAG targets the class C Vps complex to coordinate autophagosome maturation and endocytic trafficking
- (2008) Chengyu Liang et al. NATURE CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started