Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling

RIF1 Counteracts BRCA1-mediated End Resection during DNA Repair

(2013) Lin Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Small Molecule Inhibitor of Polycomb Repressive Complex 1 Inhibits Ubiquitin Signaling at DNA Double-strand Breaks

(2013) Ismail Hassan Ismail et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of the nucleosome acidic patch in modulating higher order chromatin structure

(2013) A. A. Kalashnikova et al.   Journal of the Royal Society Interface

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

(2013) J. Ross Chapman et al.   MOLECULAR CELL

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

(2013) Amélie Fradet-Turcotte et al.   NATURE

Push back to respond better: regulatory inhibition of the DNA double-strand break response

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection

(2013) M. Zimmermann et al.   SCIENCE

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

(2013) M. Di Virgilio et al.   SCIENCE

Engineered proteins detect spontaneous DNA breakage in human and bacterial cells

(2013) Chandan Shee et al.   eLife

Histone marks: repairing DNA breaks within the context of chromatin

(2012) Kyle M. Miller et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

(2012) Thorkell Gudjonsson et al.   CELL

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase

(2012) Marco Gatti et al.   CELL CYCLE

Systematic Identification of Functional Residues in Mammalian Histone H2AX

(2012) W.-T. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Tandem Protein Interaction Modules Organize the Ubiquitin-Dependent Response to DNA Double-Strand Breaks

(2012) Stephanie Panier et al.   MOLECULAR CELL

Viral E3 Ubiquitin Ligase-Mediated Degradation of a Cellular E3: Viral Mimicry of a Cellular Phosphorylation Mark Targets the RNF8 FHA Domain

(2012) Mira S. Chaurushiya et al.   MOLECULAR CELL

Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex

(2011) Matthew L Bentley et al.   EMBO JOURNAL

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Monoubiquitination of H2AX Protein Regulates DNA Damage Response Signaling

(2011) Mei-Ren Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Critical Role of Monoubiquitination of Histone H2AX Protein in Histone H2AX Phosphorylation and DNA Damage Response

(2011) Ching-Yuan Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

BMI1 Is Recruited to DNA Breaks and Contributes to DNA Damage-Induced H2A Ubiquitination and Repair

(2011) V. Ginjala et al.   MOLECULAR AND CELLULAR BIOLOGY

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR

(2011) H. Kato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An anticlastogenic function for the Polycomb Group gene Bmi1

(2011) J. Chagraoui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomes in Conflict: Maintaining Genome Integrity During Virus Infection

(2010) Matthew D. Weitzman et al.   Annual Review of Microbiology

53BP1 Inhibits Homologous Recombination in Brca1-Deficient Cells by Blocking Resection of DNA Breaks

(2010) Samuel F. Bunting et al.   CELL

Nucleosome-Interacting Proteins Regulated by DNA and Histone Methylation

(2010) Till Bartke et al.   CELL

A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses

(2010) Caroline E Lilley et al.   EMBO JOURNAL

BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair

(2010) Ismail Hassan Ismail et al.   JOURNAL OF CELL BIOLOGY

BMI1 Confers Radioresistance to Normal and Cancerous Neural Stem Cells through Recruitment of the DNA Damage Response Machinery

(2010) S. Facchino et al.   JOURNAL OF NEUROSCIENCE

Structure of RCC1 chromatin factor bound to the nucleosome core particle

(2010) Ravindra D. Makde et al.   NATURE

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

(2009) Jorrit V Tjeertes et al.   EMBO JOURNAL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Molecular mimicry between IL-33 and KSHV for attachment to chromatin through the H2A–H2B acidic pocket

(2008) Lucie Roussel et al.   EMBO REPORTS