Canine Hereditary Ataxia in Old English Sheepdogs and Gordon Setters Is Associated with a Defect in the Autophagy Gene Encoding RAB24

Rab24 is Required for Normal Cell Division

(2013) Rodrigo D. Militello et al.   TRAFFIC

The Ubiquitin-Proteasome System and the Autophagic-Lysosomal System in Alzheimer Disease

(2013) Y. Ihara et al.   Cold Spring Harbor Perspectives in Medicine

Brain pathology of spinocerebellar ataxias

(2012) Kay Seidel et al.   ACTA NEUROPATHOLOGICA

Genome-wide mRNA sequencing of a single canine cerebellar cortical degeneration case leads to the identification of a disease associated SPTBN2 mutation

(2012) Oliver P Forman et al.   BMC GENETICS

Binding of the Atg1/ULK1 kinase to the ubiquitin-like protein Atg8 regulates autophagy

(2012) Claudine Kraft et al.   EMBO JOURNAL

The inherited ataxias: Genetic heterogeneity, mutation databases, and future directions in research and clinical diagnostics

(2012) Joshua Hersheson et al.   HUMAN MUTATION

Genomic analyses of modern dog breeds

(2012) Heidi G. Parker   MAMMALIAN GENOME

Mitophagy and Parkinson's disease: Be eaten to stay healthy

(2012) Rosa L.A. de Vries et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A SEL1L Mutation Links a Canine Progressive Early-Onset Cerebellar Ataxia to the Endoplasmic Reticulum–Associated Protein Degradation (ERAD) Machinery

(2012) Kaisa Kyöstilä et al.   PLoS Genetics

Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation

(2011) Christelle En Lin Chua et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Truncated Retrotransposon Disrupts the GRM1 Coding Sequence in Coton de Tulear Dogs with Bandera's Neonatal Ataxia

(2011) R. Zeng et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Milestones in ataxia

(2011) Thomas Klockgether et al.   MOVEMENT DISORDERS

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease

(2011) Baris Bingol et al.   NEURON

Mapping of Purkinje Neuron Loss and Polyglucosan Body Accumulation in Hereditary Cerebellar Degeneration in Scottish Terriers

(2011) G. Urkasemsin et al.   VETERINARY PATHOLOGY

Role of ubiquitin–proteasome-mediated proteolysis in nervous system disease

(2010) Ashok N. Hegde et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

(2010) Brigit E. Riley et al.   JOURNAL OF CELL BIOLOGY

Hereditary Cerebellar Degeneration in Scottish Terriers

(2010) G. Urkasemsin et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication

(2010) Bridgett M. vonHoldt et al.   NATURE

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

DEVELOPMENT OF A MORPHOMETRIC MAGNETIC RESONANCE IMAGE PARAMETER SUITABLE FOR DISTINGUISHING BETWEEN NORMAL DOGS AND DOGS WITH CEREBELLAR ATROPHY

(2010) RYAN A. THAMES et al.   VETERINARY RADIOLOGY & ULTRASOUND

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

(2009) Prateek Kumar et al.   Nature Protocols

A novel missense mutation (G43S) in the switch I region of Rab27A causing Griscelli syndrome

(2008) Wendy Westbroek et al.   MOLECULAR GENETICS AND METABOLISM