Gene-Based Sequencing Identifies Lipid-Influencing Variants with Ethnicity-Specific Effects in African Americans

Lipoprotein lipase gene polymorphism rs1059611 functionally influences serum lipid concentrations

(2013) Xingbo Mo et al.   ATHEROSCLEROSIS

Trans-Ethnic Fine-Mapping of Lipid Loci Identifies Population-Specific Signals and Allelic Heterogeneity That Increases the Trait Variance Explained

(2013) Ying Wu et al.   PLoS Genetics

Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study

(2012) Juho R.H. Raiko et al.   ATHEROSCLEROSIS

Optimal tests for rare variant effects in sequencing association studies

(2012) S. Lee et al.   BIOSTATISTICS

Transferability and Fine Mapping of genome-wide associated loci for lipids in African Americans

(2012) Adebowale Adeyemo et al.   BMC Medical Genetics

MaCH-Admix: Genotype Imputation for Admixed Populations

(2012) Eric Yi Liu et al.   GENETIC EPIDEMIOLOGY

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Multi-Ethnic Analysis of Lipid-Associated Loci: The NHLBI CARe Project

(2012) Kiran Musunuru et al.   PLoS One

Multiple Loci Associated with Renal Function in African Americans

(2012) Daniel Shriner et al.   PLoS One

Association of body fat percentage with lipid concentrations in children and adolescents: United States, 1999-2004

(2011) M. M. Lamb et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Associations between common genetic polymorphisms in the liver X receptor alpha and its target genes with the serum HDL-cholesterol concentration in adolescents of the HELENA Study

(2011) Vanessa Legry et al.   ATHEROSCLEROSIS

Genetic variations at the lipoprotein lipase gene influence plasma lipid concentrations and interact with plasma n-6 polyunsaturated fatty acids to modulate lipid metabolism

(2011) Antonio Garcia-Rios et al.   ATHEROSCLEROSIS

The lipoprotein lipase (LPL) S447X gain of function variant involves increased mRNA translation

(2011) Gouri Ranganathan et al.   ATHEROSCLEROSIS

Racial/Ethnic Variation in the Association of Lipid-Related Genetic Variants With Blood Lipids in the US Adult Population

(2011) Man-huei Chang et al.   Circulation-Cardiovascular Genetics

Plasminogen activator inhibitor-1 4G/5G polymorphism is associated with metabolic syndrome parameters in Malaysian subjects

(2011) Zaid H. Al-Hamodi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

(2011) L. D. Ward et al.   NUCLEIC ACIDS RESEARCH

Genetic Determinants of Lipid Traits in Diverse Populations from the Population Architecture using Genomics and Epidemiology (PAGE) Study

(2011) Logan Dumitrescu et al.   PLoS Genetics

Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project

(2011) Guillaume Lettre et al.   PLoS Genetics

Ethnic differences in lipoprotein subclasses in obese adolescents: importance of liver and intraabdominal fat accretion

(2010) Ebe D’Adamo et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Additive effects of LPL, APOA5 and APOEvariant combinations on triglyceride levels and hypertriglyceridemia: results of the ICARIA genetic sub-study

(2010) María-José Ariza et al.   BMC Medical Genetics

Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans

(2010) E. Ramos et al.   DIABETOLOGIA

Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry

(2010) I. Miljkovic et al.   JOURNAL OF LIPID RESEARCH

Biological, clinical and population relevance of 95 loci for blood lipids

(2010) Tanya M. Teslovich et al.   NATURE

The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine

(2009) L. G. Biesecker et al.   GENOME RESEARCH

Genetic Differences between the Determinants of Lipid Profile Phenotypes in African and European Americans: The Jackson Heart Study

(2009) Rahul C. Deo et al.   PLoS Genetics

A Genome-Wide Association Study of Hypertension and Blood Pressure in African Americans

(2009) Adebowale Adeyemo et al.   PLoS Genetics

Forty-Three Loci Associated with Plasma Lipoprotein Size, Concentration, and Cholesterol Content in Genome-Wide Analysis

(2009) Daniel I. Chasman et al.   PLoS Genetics

Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis

(2008) G. S. Sagoo et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Estimating Local Ancestry in Admixed Populations

(2008) Sriram Sankararaman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk

(2008) Gaby Kressel et al.   ATHEROSCLEROSIS

Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: A systematic in-depth review

(2008) Eva Boes et al.   EXPERIMENTAL GERONTOLOGY

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations

(2008) Yingchang Lu et al.   JOURNAL OF LIPID RESEARCH

Polymorphisms Associated with Cholesterol and Risk of Cardiovascular Events

(2008) Sekar Kathiresan et al.   NEW ENGLAND JOURNAL OF MEDICINE