A Mouse Model Uncovers LKB1 as an UVB-Induced DNA Damage Sensor Mediating CDKN1A (p21WAF1/CIP1) Degradation

UV-triggered p21 degradation facilitates damaged-DNA replication and preserves genomic stability

(2013) S. F. Mansilla et al.   NUCLEIC ACIDS RESEARCH

Possible involvement of LKB1-AMPK signaling in non-homologous end joining

(2013) A Ui et al.   ONCOGENE

Lkb1 Loss Promotes Tumor Progression of BRAFV600E-Induced Lung Adenomas

(2013) Elena González-Sánchez et al.   PLoS One

LKB1/STK11 Inactivation Leads to Expansion of a Prometastatic Tumor Subpopulation in Melanoma

(2012) Wenjin Liu et al.   CANCER CELL

The p21 and PCNA partnership: A new twist for an old plot

(2011) Carol Prives et al.   CELL CYCLE

Making sense of cancer genomic data

(2011) Lynda Chin et al.   GENES & DEVELOPMENT

A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferation

(2011) X Hou et al.   ONCOGENE

Protein Arginine Methyltransferase 5 Regulates ERK1/2 Signal Transduction Amplitude and Cell Fate Through CRAF

(2011) P. Andreu-Perez et al.   Science Signaling

LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest

(2010) Jennifer P. Morton et al.   GASTROENTEROLOGY

Increased Apoptosis after Autoimmune Regulator Expression in Epithelial Cells Revealed by a Combined Quantitative Proteomics Approach

(2010) Nuria Colomé et al.   JOURNAL OF PROTEOME RESEARCH

Oncogenic B-RAF Negatively Regulates the Tumor Suppressor LKB1 to Promote Melanoma Cell Proliferation

(2009) Bin Zheng et al.   MOLECULAR CELL

Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E

(2009) Rosaura Esteve-Puig et al.   PLoS One

LKB1 Deficiency Sensitizes Mice to Carcinogen-Induced Tumorigenesis

(2008) S. Gurumurthy et al.   CANCER RESEARCH

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

(2008) T. Abbas et al.   GENES & DEVELOPMENT

CDK Inhibitor p21 Is Degraded by a Proliferating Cell Nuclear Antigen-coupled Cul4-DDB1Cdt2Pathway during S Phase and after UV Irradiation

(2008) Hideo Nishitani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation

(2008) G. Soria et al.   JOURNAL OF CELL SCIENCE

STRADα Regulates LKB1 Localization by Blocking Access to Importin-α, and by Association with Crm1 and Exportin-7

(2008) Julia Dorfman et al.   MOLECULAR BIOLOGY OF THE CELL

LKB1 and AMPK in cell polarity and division

(2008) Tyisha Williams et al.   TRENDS IN CELL BIOLOGY