Unkempt Is Negatively Regulated by mTOR and Uncouples Neuronal Differentiation from Growth Control

Rheb Activation in Subventricular Zone Progenitors Leads to Heterotopia, Ectopic Neuronal Differentiation, and Rapamycin-Sensitive Olfactory Micronodules and Dendrite Hypertrophy of Newborn Neurons

(2013) C. A. Lafourcade et al.   JOURNAL OF NEUROSCIENCE

mTORC1 Targets the Translational Repressor 4E-BP2, but Not S6 Kinase 1/2, to Regulate Neural Stem Cell Self-Renewal In Vivo

(2013) Nathaniel W. Hartman et al.   Cell Reports

Pten deletion causes mTorc1-dependent ectopic neuroblast differentiation without causing uniform migration defects

(2012) G. Zhu et al.   DEVELOPMENT

An Interaction Screen Identifies headcase as a Regulator of Large-Scale Pruning

(2012) N. Loncle et al.   JOURNAL OF NEUROSCIENCE

The mTOR Signaling Pathway in the Brain: Focus on Epilepsy and Epileptogenesis

(2012) Emilio Russo et al.   MOLECULAR NEUROBIOLOGY

An emerging role for TOR signaling in mammalian tissue and stem cell physiology

(2011) Ryan C. Russell et al.   DEVELOPMENT

Postnatal neurogenesis generates heterotopias, olfactory micronodules and cortical infiltration following single-cell Tsc1 deletion

(2011) D. M. Feliciano et al.   HUMAN MOLECULAR GENETICS

Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice

(2011) David M. Feliciano et al.   JOURNAL OF CLINICAL INVESTIGATION

RTP801/REDD1 Regulates the Timing of Cortical Neurogenesis and Neuron Migration

(2011) C. Malagelada et al.   JOURNAL OF NEUROSCIENCE

Heat Shock Cognate Protein 70 Regulates Gephyrin Clustering

(2011) P. Machado et al.   JOURNAL OF NEUROSCIENCE

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

(2011) T. Glatter et al.   Molecular Systems Biology

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

A Systematic Screen for Tube Morphogenesis and Branching Genes in the Drosophila Tracheal System

(2011) Amin S. Ghabrial et al.   PLoS Genetics

The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt

(2010) Patrick Lorès et al.   FEBS Journal

mTOR: from growth signal integration to cancer, diabetes and ageing

(2010) Roberto Zoncu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A Comprehensive Resource of Interacting Protein Regions for Refining Human Transcription Factor Networks

(2010) Etsuko Miyamoto-Sato et al.   PLoS One

Dynamic Switch of Negative Feedback Regulation in Drosophila Akt–TOR Signaling

(2010) Lutz Kockel et al.   PLoS Genetics

The tuberous sclerosis complex

(2009) Ksenia A. Orlova et al.   Annals of the New York Academy of Sciences

Determination of cell fates in the R7 equivalence group of the Drosophila eye by the concerted regulation of D-Pax2 and TTK88

(2009) Yandong Shi et al.   DEVELOPMENTAL BIOLOGY

Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube

(2009) Katherine J. Fishwick et al.   DEVELOPMENTAL BIOLOGY

The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy

(2009) L.-H. Zeng et al.   JOURNAL OF NEUROSCIENCE

Regulation of Neurogenesis and Epidermal Growth Factor Receptor Signaling by the Insulin Receptor/Target of Rapamycin Pathway in Drosophila

(2008) Helen McNeill et al.   GENETICS

Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin

(2008) Jin Han et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa

(2008) Claudio Punzo et al.   NATURE NEUROSCIENCE