Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas

Zebrafish Models for Cancer

(2011) Shu Liu et al.   Annual Review of Pathology-Mechanisms of Disease

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

(2011) Erica E Davis et al.   NATURE GENETICS

Mutation in the type IB bone morphogenetic protein receptoralk6bimpairs germ-cell differentiation and causes germ-cell tumors in zebrafish

(2011) Joanie C. Neumann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for central spindle proteins in cilia structure and function

(2010) Katherine R. Smith et al.   Cytoskeleton

Familial testicular germ cell tumors in adults: 2010 summary of genetic risk factors and clinical phenotype

(2010) Mark H Greene et al.   ENDOCRINE-RELATED CANCER

Individuals with mutations in XPNPEP3, which encodes a mitochondrial protein, develop a nephronophthisis-like nephropathy

(2010) John F. O’Toole et al.   JOURNAL OF CLINICAL INVESTIGATION

Primary Cilia Are Decreased in Breast Cancer: Analysis of a Collection of Human Breast Cancer Cell Lines and Tissues

(2010) Kun Yuan et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Loss of heterozygosity of selected tumor suppressor genes in human testicular germ cell tumors

(2010) Tomislav Vladušić et al.   PATHOLOGY RESEARCH AND PRACTICE

Identification of a Heritable Model of Testicular Germ Cell Tumor in the Zebrafish

(2010) Joanie C. Neumann et al.   Zebrafish

Histological and Stereological Evaluation of Zebrafish (Danio rerio) Spermatogenesis with an Emphasis on Spermatogonial Generations1

(2009) Marcelo C. Leal et al.   BIOLOGY OF REPRODUCTION

Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia

(2009) E. van Rooijen et al.   BLOOD

Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome

(2009) Margaret W Leigh et al.   GENETICS IN MEDICINE

Human testicular (non)seminomatous germ cell tumours: the clinical implications of recent pathobiological insights

(2009) Leendert HJ Looijenga   JOURNAL OF PATHOLOGY

Gardner's syndrome (familial adenomatous polyposis): a cilia-related disorder

(2009) Encarna B Gómez García et al.   LANCET ONCOLOGY

Zebrafish Hagoromo Mutants Up-Regulate fgf8 Postembryonically and Develop Neuroblastoma

(2009) A. Amsterdam et al.   MOLECULAR CANCER RESEARCH

FGF signalling during embryo development regulates cilia length in diverse epithelia

(2009) Judith M. Neugebauer et al.   NATURE

Cell Cycle-Dependent Ciliogenesis and Cancer

(2008) O. V. Plotnikova et al.   CANCER RESEARCH

LRRC50, a Conserved Ciliary Protein Implicated in Polycystic Kidney Disease

(2008) E. van Rooijen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Zebrafish as a Cancer Model

(2008) H. Feitsma et al.   MOLECULAR CANCER RESEARCH

Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants

(2007) Jessica Sullivan-Brown et al.   DEVELOPMENTAL BIOLOGY