标题
Molecular Networks of Human Muscle Adaptation to Exercise and Age
作者
关键词
Muscle biochemistry, Gene expression, Gene regulation, Exercise, Muscle proteins, Ribosomal RNA, Regulator genes, Skeletal muscles
出版物
PLoS Genetics
Volume 9, Issue 3, Pages e1003389
出版商
Public Library of Science (PLoS)
发表日期
2013-03-22
DOI
10.1371/journal.pgen.1003389
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Mechanical loading induces the expression of a Pol I regulon at the onset of skeletal muscle hypertrophy
- (2012) Ferdinand von Walden et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Activation of mTOR signalling in young and old human skeletal muscle in response to combined resistance exercise and whey protein ingestion
- (2012) Michelle M. Farnfield et al. Applied Physiology Nutrition and Metabolism
- Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis: Figure 1
- (2012) Valentina Iadevaia et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Suppression of Skeletal Muscle Turnover in Cancer Cachexia: Evidence from the Transcriptome in Sequential Human Muscle Biopsies
- (2012) I. J. Gallagher et al. CLINICAL CANCER RESEARCH
- Transcriptome signature of resistance exercise adaptations: mixed muscle and fiber type specific profiles in young and old adults
- (2012) Ulrika Raue et al. JOURNAL OF APPLIED PHYSIOLOGY
- Resistance exercise load does not determine training-mediated hypertrophic gains in young men
- (2012) Cameron J. Mitchell et al. JOURNAL OF APPLIED PHYSIOLOGY
- Muscle protein synthesis in response to nutrition and exercise
- (2012) P. J. Atherton et al. JOURNAL OF PHYSIOLOGY-LONDON
- Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise
- (2012) Mengyao Li et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Is irisin a human exercise gene?
- (2012) James A. Timmons et al. NATURE
- Nutritional regulation of muscle protein synthesis with resistance exercise: strategies to enhance anabolism
- (2012) Tyler A Churchward-Venne et al. Nutrition & Metabolism
- Rapid aminoacidemia enhances myofibrillar protein synthesis and anabolic intramuscular signaling responses after resistance exercise
- (2011) D. W. West et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Activation of the Aryl Hydrocarbon Receptor AhR Promotes Retinoic Acid-Induced Differentiation of Myeloblastic Leukemia Cells by Restricting Expression of the Stem Cell Transcription Factor Oct4
- (2011) R. P. Bunaciu et al. CANCER RESEARCH
- Resistance exercise training improves age-related declines in leg vascular conductance and rejuvenates acute leg blood flow responses to feeding and exercise
- (2011) Bethan Phillips et al. JOURNAL OF APPLIED PHYSIOLOGY
- IGF-II is regulated by microRNA-125b in skeletal myogenesis
- (2011) Yejing Ge et al. JOURNAL OF CELL BIOLOGY
- Emerin inhibits Lmo7 binding to the Pax3 and MyoD promoters and expression of myoblast proliferation genes
- (2011) Z. Dedeic et al. JOURNAL OF CELL SCIENCE
- Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids
- (2011) Jared M. Dickinson et al. JOURNAL OF NUTRITION
- What happens if you pose the wrong questions?
- (2011) James A. Timmons JOURNAL OF PHYSIOLOGY-LONDON
- The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth
- (2011) Craig A. Goodman et al. JOURNAL OF PHYSIOLOGY-LONDON
- Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis
- (2011) Christopher S Fry et al. Skeletal Muscle
- Resistance exercise enhances mTOR and MAPK signalling in human muscle over that seen at rest after bolus protein ingestion
- (2010) D. R. Moore et al. Acta Physiologica
- Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling
- (2010) Philip J Atherton et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Effects of 3 days unloading on molecular regulators of muscle size in humans
- (2010) T. Gustafsson et al. JOURNAL OF APPLIED PHYSIOLOGY
- Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans
- (2010) James A. Timmons et al. JOURNAL OF APPLIED PHYSIOLOGY
- Variability in training-induced skeletal muscle adaptation
- (2010) James A. Timmons JOURNAL OF APPLIED PHYSIOLOGY
- A transcriptional map of the impact of endurance exercise training on skeletal muscle phenotype
- (2010) Pernille Keller et al. JOURNAL OF APPLIED PHYSIOLOGY
- High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression
- (2010) Peter K. Davidsen et al. JOURNAL OF APPLIED PHYSIOLOGY
- Early Time Course of Akt Phosphorylation after Endurance and Resistance Exercise
- (2010) DONNY M. CAMERA et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Cyclic AMP Controls mTOR through Regulation of the Dynamic Interaction between Rheb and Phosphodiesterase 4D
- (2010) H. W. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- A Phosphatidylinositol 3-Kinase/Protein Kinase B-independent Activation of Mammalian Target of Rapamycin Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy
- (2010) Craig A. Goodman et al. MOLECULAR BIOLOGY OF THE CELL
- The genetics of ageing
- (2010) Cynthia J. Kenyon NATURE
- Myc proteins as therapeutic targets
- (2010) W C Gustafson et al. ONCOGENE
- Regulation of Muscle Satellite Cell Activation and Chemotaxis by Angiotensin II
- (2010) Adam P. W. Johnston et al. PLoS One
- Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia
- (2010) Nathan A Stephens et al. Genome Medicine
- Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes
- (2010) Iain J Gallagher et al. Genome Medicine
- Contraction intensity and feeding affect collagen and myofibrillar protein synthesis rates differently in human skeletal muscle
- (2009) Lars Holm et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Systematic analysis of adaptations in aerobic capacity and submaximal energy metabolism provides a unique insight into determinants of human aerobic performance
- (2009) Niels B. J. Vollaard et al. JOURNAL OF APPLIED PHYSIOLOGY
- Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
- (2009) David L. Mayhew et al. JOURNAL OF APPLIED PHYSIOLOGY
- Resistance exercise-induced increases in putative anabolic hormones do not enhance muscle protein synthesis or intracellular signalling in young men
- (2009) Daniel W. D. West et al. JOURNAL OF PHYSIOLOGY-LONDON
- The biology of satellite cells and telomeres in human skeletal muscle: effects of aging and physical activity
- (2009) F. Kadi et al. SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
- A Human Protein Interaction Network Shows Conservation of Aging Processes between Human and Invertebrate Species
- (2009) Russell Bell et al. PLoS Genetics
- Are animal models predictive for humans?
- (2009) Niall Shanks et al. Philosophy Ethics and Humanities in Medicine
- Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle
- (2008) P. L. Greenhaff et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis
- (2008) Micah J. Drummond et al. JOURNAL OF APPLIED PHYSIOLOGY
- Co-expression of IGF-1 family members with myogenic regulatory factors following acute damaging muscle-lengthening contractions in humans
- (2008) Bryon R. McKay et al. JOURNAL OF PHYSIOLOGY-LONDON
- Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
- (2008) Elisa I. Glover et al. JOURNAL OF PHYSIOLOGY-LONDON
- Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men
- (2008) Vinod Kumar et al. JOURNAL OF PHYSIOLOGY-LONDON
- Muscle satellite cell and atypical myogenic progenitor response following exercise
- (2008) Gianni Parise et al. MUSCLE & NERVE
- Network pharmacology: the next paradigm in drug discovery
- (2008) Andrew L Hopkins Nature Chemical Biology
- Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions
- (2008) K. De Preter et al. NUCLEIC ACIDS RESEARCH
- Dysregulation of Mitochondrial Dynamics and the Muscle Transcriptome in ICU Patients Suffering from Sepsis Induced Multiple Organ Failure
- (2008) Katarina Fredriksson et al. PLoS One
- A functional insulin-like growth factor receptor is not necessary for load-induced skeletal muscle hypertrophy
- (2007) Espen E. Spangenburg et al. JOURNAL OF PHYSIOLOGY-LONDON
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