The Identification of Trans-acting Factors That Regulate the Expression of GDF5 via the Osteoarthritis Susceptibility SNP rs143383

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

(2012)   LANCET

Expression of the osteoarthritis-associated gene GDF5 is modulated epigenetically by DNA methylation

(2011) Louise N. Reynard et al.   HUMAN MOLECULAR GENETICS

The p65 Subunit of NF-κB InhibitsCOL1A1Gene Transcription in Human Dermal and Scleroderma Fibroblasts through Its Recruitment on Promoter by Protein Interaction with Transcriptional Activators (c-Krox, Sp1, and Sp3)

(2011) Gallic Beauchef et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perturbations of Amino Acid Metabolism Associated with Glyphosate-Dependent Inhibition of Shikimic Acid Metabolism Affect Cellular Redox Homeostasis and Alter the Abundance of Proteins Involved in Photosynthesis and Photorespiration

(2011) Pedro Diaz Vivancos et al.   PLANT PHYSIOLOGY

GDF5 deficiency in mice is associated with instability-driven joint damage, gait and subchondral bone changes

(2010) M. Daans et al.   ANNALS OF THE RHEUMATIC DISEASES

GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women

(2010) F. M. K. Williams et al.   ARTHRITIS AND RHEUMATISM

Coactivator Function of Positive Cofactor 4 (PC4) in Sp1-directed Luteinizing Hormone Receptor (LHR) Gene Transcription

(2010) Mingjuan Liao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Components of the transforming growth factor-  family and the pathogenesis of human Achilles tendon pathology--a genetic association study

(2010) M. Posthumus et al.   RHEUMATOLOGY

Sub1/PC4 a chromatin associated protein with multiple functions in transcription

(2010) Christine Conesa et al.   RNA Biology

Functional analysis of the osteoarthritis susceptibility-associatedGDF5regulatory polymorphism

(2009) Rainer J. Egli et al.   ARTHRITIS AND RHEUMATISM

Deaf1 isoforms control the expression of genes encoding peripheral tissue antigens in the pancreatic lymph nodes during type 1 diabetes

(2009) Linda Yip et al.   NATURE IMMUNOLOGY

Genetic variation in the GDF5 region is associated with osteoarthritis, height, hip axis length and fracture risk: the Rotterdam study

(2008) R B A Vaes et al.   ANNALS OF THE RHEUMATIC DISEASES

A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility

(2008) K. Chapman et al.   HUMAN MOLECULAR GENETICS

Co-stimulation of the Bone-relatedRunx2P1 Promoter in Mesenchymal Cells by SP1 and ETS Transcription Factors at Polymorphic Purine-rich DNA Sequences (Y-repeats)

(2008) Ying Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel point mutations in GDF5 associated with two distinct limb malformations in Chinese: brachydactyly type C and proximal symphalangism

(2008) Wei Yang et al.   JOURNAL OF HUMAN GENETICS

Targeting transcription factors for therapeutic benefit

(2008) Paul Brennan et al.   Molecular BioSystems

Common variants in the GDF5-UQCC region are associated with variation in human height

(2008) Serena Sanna et al.   NATURE GENETICS

DEAF-1 regulates immunity gene expression in Drosophila

(2008) D. E. Reed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Etiopathogenesis of Osteoarthritis

(2008) Kenneth D. Brandt et al.   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study

(2008) Jin Dai et al.   ARTHRITIS RESEARCH & THERAPY