A Combination of H2A.Z and H4 Acetylation Recruits Brd2 to Chromatin during Transcriptional Activation

H2A.Z.2.2 is an alternatively spliced histone H2A.Z variant that causes severe nucleosome destabilization

(2012) Clemens Bönisch et al.   NUCLEIC ACIDS RESEARCH

Proteome analysis of protein partners to nucleosomes containing canonical H2A or the variant histones H2A.Z or H2A.X

(2011) Satoru Fujimoto et al.   BIOLOGICAL CHEMISTRY

Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails

(2011) Ina Bock et al.   BMC BIOCHEMISTRY

Histone H2A.Z prepares the prostate specific antigen (PSA) gene for androgen receptor-mediated transcription and is upregulated in a model of prostate cancer progression

(2011) Deanna Dryhurst et al.   CANCER LETTERS

Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions

(2011) Alexander J. Ruthenburg et al.   CELL

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Recognition of Multivalent Histone States Associated with Heterochromatin by UHRF1 Protein

(2011) Nataliya Nady et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In-Depth Proteomics of Ovarian Cancer Ascites: Combining Shotgun Proteomics and Selected Reaction Monitoring Mass Spectrometry

(2011) Sarah Elschenbroich et al.   JOURNAL OF PROTEOME RESEARCH

Recruitment of TIF1γ to Chromatin via Its PHD Finger-Bromodomain Activates Its Ubiquitin Ligase and Transcriptional Repressor Activities

(2011) Eleonora Agricola et al.   MOLECULAR CELL

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

(2011) Johannes Zuber et al.   NATURE

Combinatorial readout of histone H3 modifications specifies localization of ATRX to heterochromatin

(2011) Sebastian Eustermann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

USP10 deubiquitylates the histone variant H2A.Z and both are required for androgen receptor-mediated gene activation

(2011) Ryan Draker et al.   NUCLEIC ACIDS RESEARCH

Distinct Factors Control Histone Variant H3.3 Localization at Specific Genomic Regions

(2010) Aaron D. Goldberg et al.   CELL

Histone Tails: Ideal Motifs for Probing Epigenetics through Chemical Biology Approaches

(2010) Philipp Voigt et al.   CHEMBIOCHEM

Structural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2

(2010) Takashi Umehara et al.   FEBS LETTERS

The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3

(2010) P. Drane et al.   GENES & DEVELOPMENT

Structural Basis for Acetylated Histone H4 Recognition by the Human BRD2 Bromodomain

(2010) Takashi Umehara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In-Depth Proteomic Analyses of Direct Expressed Prostatic Secretions

(2010) Richard R. Drake et al.   JOURNAL OF PROTEOME RESEARCH

Selective inhibition of BET bromodomains

(2010) Panagis Filippakopoulos et al.   NATURE

Identification and characterization of the two isoforms of the vertebrate H2A.Z histone variant

(2010) Ryo Matsuda et al.   NUCLEIC ACIDS RESEARCH

Single Cell Analysis of Transcriptional Activation Dynamics

(2010) Ilona U. Rafalska-Metcalf et al.   PLoS One

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

(2010) P. W. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles for H2A.Z and Its Acetylation in GAL1 Transcription and Gene Induction, but Not GAL1-Transcriptional Memory

(2010) Jeffrey E. Halley et al.   PLOS BIOLOGY

Brd2disruption in mice causes severe obesity without Type 2 diabetes

(2009) Fangnian Wang et al.   BIOCHEMICAL JOURNAL

Acetylation of Vertebrate H2A.Z and Its Effect on the Structure of the Nucleosome

(2009) Toyotaka Ishibashi et al.   BIOCHEMISTRY

The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis

(2009) Aron Gyuris et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Characterization of the histone H2A.Z-1 and H2A.Z-2 isoforms in vertebrates

(2009) Deanna Dryhurst et al.   BMC BIOLOGY

The evolutionary differentiation of two histone H2A.Z variants in chordates (H2A.Z-1 and H2A.Z-2) is mediated by a stepwise mutation process that affects three amino acid residues

(2009) José M Eirín-López et al.   BMC EVOLUTIONARY BIOLOGY

Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse

(2009) Enyuan Shang et al.   DEVELOPMENTAL DYNAMICS

Histone Variant H2A.Z Regulates Centromere Silencing and Chromosome Segregation in Fission Yeast

(2009) Haitong Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Automated 2D Peptide Separation on a 1D Nano-LC-MS System

(2009) Paul Taylor et al.   JOURNAL OF PROTEOME RESEARCH

Nap1 and Chz1 have Separate Htz1 Nuclear Import and Assembly Functions

(2009) Korinna Straube et al.   TRAFFIC

The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription

(2008) Gary LeRoy et al.   MOLECULAR CELL

Structural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300

(2008) Lei Zeng et al.   STRUCTURE