Signatures of Environmental Genetic Adaptation Pinpoint Pathogens as the Main Selective Pressure through Human Evolution

Balancing Selection Is the Main Force Shaping the Evolution of Innate Immunity Genes

(2014) A. Ferrer-Admetlla et al.   JOURNAL OF IMMUNOLOGY

GeCo++: a C++ library for genomic features computation and annotation in the presence of variants

(2011) M. Cereda et al.   BIOINFORMATICS

Innate Immune Sensing of Retroviral Infection via Toll-like Receptor 7 Occurs upon Viral Entry

(2011) Melissa Kane et al.   IMMUNITY

Bacteroides fragilis–Stimulated Interleukin-10 Contains Expanding Disease

(2011) Ronit Cohen-Poradosu et al.   JOURNAL OF INFECTIOUS DISEASES

Retraction Note to: The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88

(2011) Padmam Puneet et al.   NATURE IMMUNOLOGY

Adaptations to Climate-Mediated Selective Pressures in Humans

(2011) Angela M. Hancock et al.   PLoS Genetics

The landscape of human genes involved in the immune response to parasitic worms

(2010) Matteo Fumagalli et al.   BMC EVOLUTIONARY BIOLOGY

The Genetics of Human Adaptation: Hard Sweeps, Soft Sweeps, and Polygenic Adaptation

(2010) Jonathan K. Pritchard et al.   CURRENT BIOLOGY

Using Environmental Correlations to Identify Loci Underlying Local Adaptation

(2010) G. Coop et al.   GENETICS

Population differentiation as a test for selective sweeps

(2010) H. Chen et al.   GENOME RESEARCH

Long-term balancing selection maintains trans-specific polymorphisms in the human TRIM5 gene

(2010) R. Cagliani et al.   HUMAN GENETICS

Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection

(2010) R. Cagliani et al.   HUMAN MOLECULAR GENETICS

The hygiene hypothesis: an evolutionary perspective

(2010) Manuela Sironi et al.   MICROBES AND INFECTION

Population Genetics of IFIH1: Ancient Population Structure, Local Selection, and Implications for Susceptibility to Type 1 Diabetes

(2010) M. Fumagalli et al.   MOLECULAR BIOLOGY AND EVOLUTION

Ascertainment Biases in SNP Chips Affect Measures of Population Divergence

(2010) A. Albrechtsen et al.   MOLECULAR BIOLOGY AND EVOLUTION

Integrating common and rare genetic variation in diverse human populations

(2010)   NATURE

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Adaptations to new environments in humans: the role of subtle allele frequency shifts

(2010) A. M. Hancock et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency

(2010) A. M. Hancock et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Composite of Multiple Signals Distinguishes Causal Variants in Regions of Positive Selection

(2010) S. R. Grossman et al.   SCIENCE

The role of protozoa-driven selection in shaping human genetic variability

(2010) Uberto Pozzoli et al.   TRENDS IN GENETICS

Human Population Differentiation Is Strongly Correlated with Local Recombination Rate

(2010) Alon Keinan et al.   PLoS Genetics

Balancing Selection Maintains a Form of ERAP2 that Undergoes Nonsense-Mediated Decay and Affects Antigen Presentation

(2010) Aida M. Andrés et al.   PLoS Genetics

Genome-Wide Identification of Susceptibility Alleles for Viral Infections through a Population Genetics Approach

(2010) Matteo Fumagalli et al.   PLoS Genetics

Fewer permutations, more accurate P-values

(2009) Theo A. Knijnenburg et al.   BIOINFORMATICS

A bootstrap goodness of fit test for the generalized Pareto distribution

(2009) José A. Villaseñor-Alva et al.   COMPUTATIONAL STATISTICS & DATA ANALYSIS

A population genetics study of the Familial Mediterranean Fever gene: evidence of balancing selection under an overdominance regime

(2009) M Fumagalli et al.   GENES AND IMMUNITY

Signals of recent positive selection in a worldwide sample of human populations

(2009) J. K. Pickrell et al.   GENOME RESEARCH

Molecular evolution of the antiretroviral TRIM5 gene

(2009) Welkin E. Johnson et al.   IMMUNOGENETICS

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

(2009) Matteo Fumagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

From evolutionary genetics to human immunology: how selection shapes host defence genes

(2009) Luis B. Barreiro et al.   NATURE REVIEWS GENETICS

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolutionary Dynamics of Human Toll-Like Receptors and Their Different Contributions to Host Defense

(2009) Luis B. Barreiro et al.   PLoS Genetics

The Role of Geography in Human Adaptation

(2009) Graham Coop et al.   PLoS Genetics

Complex signatures of selection for the melanogenic loci TYR, TYRP1 and DCT in humans

(2008) Santos Alonso et al.   BMC EVOLUTIONARY BIOLOGY

Widespread balancing selection and pathogen-driven selection at blood group antigen genes

(2008) M. Fumagalli et al.   GENOME RESEARCH

Evolutionary dynamics of the human ABO gene

(2008) Francesc Calafell et al.   HUMAN GENETICS

Natural selection has driven population differentiation in modern humans

(2008) Luis B Barreiro et al.   NATURE GENETICS

Adaptations to Climate in Candidate Genes for Common Metabolic Disorders

(2008) Angela M. Hancock et al.   PLoS Genetics

Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

(2008) J. Z. Li et al.   SCIENCE

The signature of long-standing balancing selection at the human defensin β-1 promoter

(2008) Rachele Cagliani et al.   GENOME BIOLOGY