Variance of Gene Expression Identifies Altered Network Constraints in Neurological Disease

Disease-specific, neurosphere-derived cells as models for brain disorders

(2010) N. Matigian et al.   Disease Models & Mechanisms

Variability in gene expression underlies incomplete penetrance

(2010) Arjun Raj et al.   NATURE

Missing heritability and strategies for finding the underlying causes of complex disease

(2010) Evan E. Eichler et al.   NATURE REVIEWS GENETICS

Wwp2 mediates Oct4 ubiquitination and its own auto-ubiquitination in a dosage-dependent manner

(2009) Bing Liao et al.   CELL RESEARCH

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2

(2009) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Decanalization and the origin of complex disease

(2009) Greg Gibson   NATURE REVIEWS GENETICS

A Continuum of Cell States Spans Pluripotency and Lineage Commitment in Human Embryonic Stem Cells

(2009) Shelley R. Hough et al.   PLoS One

Stochastic epigenetic variation as a driving force of development, evolutionary adaptation, and disease

(2009) A. P. Feinberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

(2009) Tibor Kalmar et al.   PLOS BIOLOGY

Reduced tumor growth in a mouse model of schizophrenia, lacking the dopamine transporter

(2008) Masanori Asada et al.   INTERNATIONAL JOURNAL OF CANCER

Fibroblast and Lymphoblast Gene Expression Profiles in Schizophrenia: Are Non-Neural Cells Informative?

(2008) Nicholas A. Matigian et al.   PLoS One

Olfactory Mucosa Is a Potential Source for Autologous Stem Cell Therapy for Parkinson's Disease

(2008) Wayne Murrell et al.   STEM CELLS

Cell-to-Cell Stochastic Variation in Gene Expression Is a Complex Genetic Trait

(2008) Juliet Ansel et al.   PLoS Genetics