Activation of Mutant Enzyme Function In Vivo by Proteasome Inhibitors and Treatments that Induce Hsp70

Beyond Li Fraumeni Syndrome: Clinical Characteristics of Families Withp53Germline Mutations

(2009) Kelly D. Gonzalez et al.   JOURNAL OF CLINICAL ONCOLOGY

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

(2008) R. Z. Orlowski et al.   CLINICAL CANCER RESEARCH

Proteasome Inhibition: A Promising Strategy for Treating Cancer, but What About Neurotoxicity?

(2008) A. Gilardini et al.   CURRENT MEDICINAL CHEMISTRY

Mouse models of cystathionine β-synthase deficiency reveal significant threshold effects of hyperhomocysteinemia

(2008) Sapna Gupta et al.   FASEB JOURNAL

Cystathionine β-synthase p.S466L mutation causes hyperhomocysteinemia in mice

(2008) Sapna Gupta et al.   HUMAN MUTATION

Functional Rescue of Mutant Human Cystathionine β-Synthase by Manipulation of Hsp26 and Hsp70 Levels inSaccharomyces cerevisiae

(2008) Laishram R. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arimoclomol at dosages up to 300 mg/day is well tolerated and safe in amyotrophic lateral sclerosis

(2008) Merit E. Cudkowicz et al.   MUSCLE & NERVE

Partial Restoration of Mutant Enzyme Homeostasis in Three Distinct Lysosomal Storage Disease Cell Lines by Altering Calcium Homeostasis

(2008) Ting-Wei Mu et al.   PLOS BIOLOGY