Gag-Pol Processing during HIV-1 Virion Maturation: A Systems Biology Approach

The Choreography of HIV-1 Proteolytic Processing and Virion Assembly

(2012) Sook-Kyung Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy

(2012) Tanmay A. M. Bharat et al.   NATURE

Kinetic characterization of the critical step in HIV-1 protease maturation

(2012) S. K. Sadiq et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity

(2012) Noortje M van Maarseveen et al.   Retrovirology

HIV Type 1 Gag as a Target for Antiviral Therapy

(2011) Abdul A. Waheed et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

A Cleavage Enzyme-Cytometric Bead Array Provides Biochemical Profiling of Resistance Mutations in HIV-1 Gag and Protease

(2011) Sebastian Breuer et al.   BIOCHEMISTRY

Kinetics of the viral cycle influence pharmacodynamics of antiretroviral therapy

(2011) Ahmad R Sedaghat et al.   Biology Direct

Cell-to-Cell Transfer of HIV-1 via Virological Synapses Leads to Endosomal Virion Maturation that Activates Viral Membrane Fusion

(2011) Benjamin M. Dale et al.   Cell Host & Microbe

Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals

(2011) Akil Jackson et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Visualizing HIV-1 Assembly

(2011) Nolwenn Jouvenet et al.   JOURNAL OF MOLECULAR BIOLOGY

The Molecular Architecture of HIV

(2011) John A.G. Briggs et al.   JOURNAL OF MOLECULAR BIOLOGY

Reaction Kinetics of Catalyzed Competitive Heteropolymer Cleavage

(2011) S. Kashif Sadiq et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Critical Subset Model Provides a Conceptual Basis for the High Antiviral Activity of Major HIV Drugs

(2011) L. Shen et al.   Science Translational Medicine

Drug Effectiveness Explained: The Mathematics of Antiviral Agents for HIV

(2011) A. S. Perelson et al.   Science Translational Medicine

A model of yeast cell-cycle regulation based on multisite phosphorylation

(2010) Debashis Barik et al.   Molecular Systems Biology

The capsid-spacer peptide 1 Gag processing intermediate is a dominant-negative inhibitor of HIV-1 maturation

(2010) Mary Ann Checkley et al.   VIROLOGY

Cell-to-Cell Spread of Retroviruses

(2010) Quentin J. Sattentau   Viruses-Basel

Current Estimates for HIV-1 Production Imply Rapid Viral Clearance in Lymphoid Tissues

(2010) Rob J. De Boer et al.   PLoS Computational Biology

Structural Analysis of HIV-1 Maturation Using Cryo-Electron Tomography

(2010) Alex de Marco et al.   PLoS Pathogens

Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance

(2009) Annemarie M.J. Wensing et al.   ANTIVIRAL RESEARCH

Intracellular ‘boosting’ of darunavir using known transport inhibitors in primary PBMC

(2009) Wai San Kwan et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Virus maturation as a new HIV-1 therapeutic target

(2009) Catherine S Adamson et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity

(2009) Barbara Müller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Folding Free-Energy Surface of HIV-1 Protease: Insights into the Thermodynamic Basis for Resistance to Inhibitors

(2009) Amanda F. Noel et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure and assembly of immature HIV

(2009) J. A. G. Briggs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamics of HIV-1 Assembly and Release

(2009) Sergey Ivanchenko et al.   PLoS Pathogens

Three-Dimensional Analysis of Budding Sites and Released Virus Suggests a Revised Model for HIV-1 Morphogenesis

(2008) Lars-Anders Carlson et al.   Cell Host & Microbe

Analysis of a budding yeast cell cycle model using the shapes of local sensitivity functions

(2008) A. Lovrics et al.   INTERNATIONAL JOURNAL OF CHEMICAL KINETICS

Importance of Protease Cleavage Sites within and Flanking Human Immunodeficiency Virus Type 1 Transframe Protein p6* for Spatiotemporal Regulation of Protease Activation

(2008) C. Ludwig et al.   JOURNAL OF VIROLOGY

Imaging the biogenesis of individual HIV-1 virions in live cells

(2008) Nolwenn Jouvenet et al.   NATURE

Dose-response curve slope sets class-specific limits on inhibitory potential of anti-HIV drugs

(2008) Lin Shen et al.   NATURE MEDICINE