Deciphering the Arginine-Binding Preferences at the Substrate-Binding Groove of Ser/Thr Kinases by Computational Surface Mapping

The Delivery of Biologically Active (Therapeutic) Peptides and Proteins into Cells

(2011) M. Grdisa   CURRENT MEDICINAL CHEMISTRY

Backbone Cyclic Peptide Inhibitors of Protein Kinase B (PKB/Akt)

(2011) Yftah Tal-Gan et al.   JOURNAL OF MEDICINAL CHEMISTRY

An orthosteric inhibitor of the Ras-Sos interaction

(2011) Anupam Patgiri et al.   Nature Chemical Biology

T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension

(2011) P. Di Tommaso et al.   NUCLEIC ACIDS RESEARCH

Computational design of peptide ligands

(2011) Peter Vanhee et al.   TRENDS IN BIOTECHNOLOGY

Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases

(2010) Kenneth M. Comess et al.   ACS Chemical Biology

The Synergistic Use of Computation, Chemistry and Biology to Discover Novel Peptide-Based Drugs: The Time is Right

(2010) J. Audie et al.   CURRENT PHARMACEUTICAL DESIGN

A Summary of Computational Resources for Protein Phosphorylation

(2010) Yu Xue et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Computational Approaches for Fragment-Based and De Novo Design

(2010) Kathryn Loving et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Computational Mapping of Anchoring Spots on Protein Surfaces

(2010) Avraham Ben-Shimon et al.   JOURNAL OF MOLECULAR BIOLOGY

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

(2010) Michelle L Stewart et al.   Nature Chemical Biology

cAMP-dependent protein kinase: Crystallographic insights into substrate recognition and phosphotransfer

(2010) Madhusudan et al.   PROTEIN SCIENCE

Protein kinases: evolution of dynamic regulatory proteins

(2010) Susan S. Taylor et al.   TRENDS IN BIOCHEMICAL SCIENCES

Identification of substrates for Ser/Thr kinases using residue-based statistical pair potentials

(2009) Narendra Kumar et al.   BIOINFORMATICS

Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques

(2009) Ryan Brenke et al.   BIOINFORMATICS

Peptidic modulators of protein-protein interactions: Progress and challenges in computational design

(2009) Mor Rubinstein et al.   BIOPOLYMERS

Structural biology contributions to tyrosine kinase drug discovery

(2009) Sandra W Cowan-Jacob et al.   CURRENT OPINION IN CELL BIOLOGY

Peptide Inhibitors Targeting Protein Kinases

(2009) Hagit Eldar-Finkelman et al.   CURRENT PHARMACEUTICAL DESIGN

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

BlockMaster: Partitioning Protein Kinase Structures Using Normal-Mode Analysis†

(2009) Marina Shudler et al.   JOURNAL OF PHYSICAL CHEMISTRY A

The nuts and bolts of AGC protein kinases

(2009) Laura R. Pearce et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Accurate Prediction of Peptide Binding Sites on Protein Surfaces

(2009) Evangelia Petsalaki et al.   PLoS Computational Biology

Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sites

(2008) Neil FW Saunders et al.   BMC BIOINFORMATICS

MAP3Ks as central regulators of cell fate during development

(2008) Evisabel A. Craig et al.   DEVELOPMENTAL DYNAMICS

Prevention of insulin resistance and beta-cell loss by abrogating PKCε-induced serine phosphorylation of muscle IRS-1 inPsammomys obesus

(2008) Esther Mack et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Synthesis of a Novel Macrocyclic Library: Discovery of an IGF-1R Inhibitor

(2008) Nir Qvit et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

The Predikin webserver: improved prediction of protein kinase peptide specificity using structural information

(2008) N. F. W. Saunders et al.   NUCLEIC ACIDS RESEARCH