Functional Genomics Complements Quantitative Genetics in Identifying Disease-Gene Associations

Bioinformatics challenges for genome-wide association studies

(2010) J. H. Moore et al.   BIOINFORMATICS

Prevalent fractures are related to cortical bone geometry in young healthy men at age of peak bone mass

(2010) Youri Taes et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mouse BMD quantitative trait loci show improved concordance with human genome-wide association loci when recalculated on a new, common mouse genetic map

(2010) Cheryl L Ackert-Bicknell et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana

(2010) Insuk Lee et al.   NATURE BIOTECHNOLOGY

Emerging new paradigms for ABCG transporters

(2009) Paul T. Tarr et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Exploring the human genome with functional maps

(2009) C. Huttenhower et al.   GENOME RESEARCH

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

(2009) Fernando Rivadeneira et al.   NATURE GENETICS

Mapping complex disease traits with global gene expression

(2009) William Cookson et al.   NATURE REVIEWS GENETICS

The genetics of quantitative traits: challenges and prospects

(2009) Trudy F. C. Mackay et al.   NATURE REVIEWS GENETICS

Global Prediction of Tissue-Specific Gene Expression and Context-Dependent Gene Networks in Caenorhabditis elegans

(2009) Maria D. Chikina et al.   PLoS Computational Biology

Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network

(2009) Bolan Linghu et al.   GENOME BIOLOGY

VisANT: an integrative framework for networks in systems biology

(2008) Z. Hu et al.   BRIEFINGS IN BIOINFORMATICS

Strain-Specific Effects of Rosiglitazone on Bone Mass, Body Composition, and Serum Insulin-Like Growth Factor-I

(2008) Cheryl L. Ackert-Bicknell et al.   ENDOCRINOLOGY

Single nucleotide polymorphisms in new candidate genes are associated with bone mineral density and fracture risk

(2008) Áron Lazáry et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Hyperlipidemia Impairs Osteoanabolic Effects of PTH

(2008) Michael S Huang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans

(2008) Insuk Lee et al.   NATURE GENETICS

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS

A Genomewide Functional Network for the Laboratory Mouse

(2008) Yuanfang Guan et al.   PLoS Computational Biology

Predicting gene function in a hierarchical context with an ensemble of classifiers

(2008) Yuanfang Guan et al.   GENOME BIOLOGY