Identifying Drug Effects via Pathway Alterations using an Integer Linear Programming Optimization Formulation on Phosphoproteomic Data

Off-Target Decoding of a Multitarget Kinase Inhibitor by Chemical Proteomics

(2009) Enrico Missner et al.   CHEMBIOCHEM

Logic Integer Programming Models for Signaling Networks

(2009) Utz-Uwe Haus et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Identifying Network of Drug Mode of Action by Gene Expression Profiling

(2009) Francesco Iorio et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Identifying the proteins to which small-molecule probes and drugs bind in cells

(2009) S.-E. Ong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor-PI3K Axis

(2009) B. Schoeberl et al.   Science Signaling

Fuzzy Logic Analysis of Kinase Pathway Crosstalk in TNF/EGF/Insulin-Induced Signaling

(2009) Bree B. Aldridge et al.   PLoS Computational Biology

Hypergraphs and Cellular Networks

(2009) Steffen Klamt et al.   PLoS Computational Biology

Review article: pharmacological therapy for hepatocellular carcinoma with sorafenib and other oral agents

(2008) M. CHAPARRO et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Flexible informatics for linking experimental data to mathematical models via DataRail

(2008) Julio Saez-Rodriguez et al.   BIOINFORMATICS

Optimal automatic reaction and species elimination in kinetic mechanisms

(2008) A. Mitsos et al.   COMBUSTION AND FLAME

Models from experiments: combinatorial drug perturbations of cancer cells

(2008) Sven Nelander et al.   Molecular Systems Biology

A quantitative analysis of kinase inhibitor selectivity

(2008) Mazen W Karaman et al.   NATURE BIOTECHNOLOGY

High-throughput kinase profiling as a platform for drug discovery

(2008) David M. Goldstein et al.   NATURE REVIEWS DRUG DISCOVERY

A short-term operational planning model for natural gas production systems

(2007) Ajay Selot et al.   AICHE JOURNAL