Evolutionary diversification of the HAP2 membrane insertion motifs to drive gamete fusion across eukaryotes

A Combinatorial Lipid Code Shapes the Electrostatic Landscape of Plant Endomembranes

(2018) Matthieu Pierre Platre et al.   DEVELOPMENTAL CELL

ArabidopsisHAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogens

(2017) Clari Valansi et al.   JOURNAL OF CELL BIOLOGY

A glycerophospholipid-specific pocket in the RVFV class II fusion protein drives target membrane insertion

(2017) P. Guardado-Calvo et al.   SCIENCE

Targeting the Conserved Fusion Loop of HAP2 Inhibits the Transmission of Plasmodium berghei and falciparum

(2017) Fiona Angrisano et al.   Cell Reports

Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion

(2016) Steinar Halldorsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc

(2016) Pablo Guardado-Calvo et al.   PLoS Pathogens

The cytoplasmic domain of the gamete membrane fusion protein HAP2 targets the protein to the fusion site in Chlamydomonas and regulates the fusion reaction

(2015) Y. Liu et al.   DEVELOPMENT

The Pfam protein families database: towards a more sustainable future

(2015) Robert D. Finn et al.   NUCLEIC ACIDS RESEARCH

Viral membrane fusion

(2015) Stephen C. Harrison   VIROLOGY

Effects of Different Maturation Systems on Bovine Oocyte Quality, Plasma Membrane Phospholipid Composition and Resistance to Vitrification and Warming

(2015) José F. W. Sprícigo et al.   PLoS One

A Higher Level Classification of All Living Organisms

(2015) Michael A. Ruggiero et al.   PLoS One

Evidence for participation of GCS1 in fertilization of the starlet sea anemone Nematostella vectensis: Implication of a common mechanism of sperm–egg fusion in plants and animals

(2014) Eerdundagula Ebchuqin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structural Basis of Eukaryotic Cell-Cell Fusion

(2014) Jimena Pérez-Vargas et al.   CELL

The three lives of viral fusion peptides

(2014) Beatriz Apellániz et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Function of the Male-Gamete-Specific Fusion Protein HAP2 in a Seven-Sexed Ciliate

(2014) Eric S. Cole et al.   CURRENT BIOLOGY

Sex-Specific Posttranslational Regulation of the Gamete Fusogen GCS1 in the Isogamous Volvocine Alga Gonium pectorale

(2014) Hiroko Kawai-Toyooka et al.   EUKARYOTIC CELL

Membrane Lipid Phase Transition Behavior of Oocytes from Three Gorgonian Corals in Relation to Chilling Injury

(2014) Chiahsin Lin et al.   PLoS One

Functional and evolutionary insight from the crystal structure of rubella virus protein E1

(2013) Rebecca M. DuBois et al.   NATURE

Crystal structure of glycoprotein C from Rift Valley fever virus

(2013) M. Dessau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Egg Cell-Secreted EC1 Triggers Sperm Cell Activation During Double Fertilization

(2012) S. Sprunck et al.   SCIENCE

Improvement of molecular-replacement models withSculptor

(2011) Gábor Bunkóczi et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Live-Cell Imaging Reveals the Dynamics of Two Sperm Cells during Double Fertilization in Arabidopsis thaliana

(2011) Yuki Hamamura et al.   CURRENT BIOLOGY

ANODE: anomalous and heavy-atom density calculation

(2011) Andrea Thorn et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

A Detailed History of Intron-rich Eukaryotic Ancestors Inferred from a Global Survey of 100 Complete Genomes

(2011) Miklos Csuros et al.   PLoS Computational Biology

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The complete influenza hemagglutinin fusion domain adopts a tight helical hairpin arrangement at the lipid:water interface

(2010) J. L. Lorieau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Is HAP2-GCS1 an ancestral gamete fusogen?

(2010) Julian L. Wong et al.   TRENDS IN CELL BIOLOGY

The Disulfide Bonds in Glycoprotein E2 of Hepatitis C Virus Reveal the Tertiary Organization of the Molecule

(2010) Thomas Krey et al.   PLoS Pathogens

Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

(2009) V. Nayak et al.   JOURNAL OF VIROLOGY

Evolutionary History of the HAP2/GCS1 Gene and Sexual Reproduction in Metazoans

(2009) Robert E. Steele et al.   PLoS One

HELIQUEST: a web server to screen sequences with specific  -helical properties

(2008) R. Gautier et al.   BIOINFORMATICS

Male Fertility of Malaria Parasites Is Determined by GCS1, a Plant-Type Reproduction Factor

(2008) Makoto Hirai et al.   CURRENT BIOLOGY

The conserved plant sterility gene HAP2 functions after attachment of fusogenic membranes in Chlamydomonas and Plasmodium gametes

(2008) Y. Liu et al.   GENES & DEVELOPMENT

Viral membrane fusion

(2008) Stephen C Harrison   NATURE STRUCTURAL & MOLECULAR BIOLOGY