In Silico Molecular Comparisons of C. elegans and Mammalian Pharmacology Identify Distinct Targets That Regulate Feeding

A pharmacological organization of G protein–coupled receptors

(2013) Henry Lin et al.   NATURE METHODS

Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells

(2012) Eleftherios Sachlos et al.   CELL

AMP-Activated Kinase Links Serotonergic Signaling to Glutamate Release for Regulation of Feeding Behavior in C. elegans

(2012) Katherine A. Cunningham et al.   Cell Metabolism

Serotonin Activates Overall Feeding by Activating Two Separate Neural Pathways in Caenorhabditis elegans

(2012) B.-m. Song et al.   JOURNAL OF NEUROSCIENCE

Deconstruction of a neural circuit for hunger

(2012) Deniz Atasoy et al.   NATURE

From neuroanatomy to behavior: central integration of peripheral signals regulating feeding behavior

(2012) Kevin W Williams et al.   NATURE NEUROSCIENCE

Vasopressin/Oxytocin-Related Signaling Regulates Gustatory Associative Learning in C. elegans

(2012) I. Beets et al.   SCIENCE

Oxytocin/Vasopressin-Related Peptides Have an Ancient Role in Reproductive Behavior

(2012) J. L. Garrison et al.   SCIENCE

Dissecting a central flip-flop circuit that integrates contradictory sensory cues in C. elegans feeding regulation

(2012) Zhaoyu Li et al.   Nature Communications

Chemical Genetics–Based Target Identification in Drug Discovery

(2011) Feng Cong et al.   Annual Review of Pharmacology and Toxicology

Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons

(2011) Hsien-Sung Huang et al.   NATURE

Chemical informatics and target identification in a zebrafish phenotypic screen

(2011) Christian Laggner et al.   Nature Chemical Biology

A whole-organism screen identifies new regulators of fat storage

(2011) George A Lemieux et al.   Nature Chemical Biology

Dafadine inhibits DAF-9 to promote dauer formation and longevity of Caenorhabditis elegans

(2011) Genna M Luciani et al.   Nature Chemical Biology

Neuropeptide Exocytosis Involving Synaptotagmin-4 and Oxytocin in Hypothalamic Programming of Body Weight and Energy Balance

(2011) Guo Zhang et al.   NEURON

The Chemical Basis of Pharmacology

(2010) Michael J. Keiser et al.   BIOCHEMISTRY

Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells

(2010) Soo Jeong Choi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Lipid droplets as ubiquitous fat storage organelles in C. elegans

(2010) Shaobing O Zhang et al.   BMC CELL BIOLOGY

Extended-Connectivity Fingerprints

(2010) David Rogers et al.   Journal of Chemical Information and Modeling

The Fat-Induced Satiety Factor Oleoylethanolamide Suppresses Feeding through Central Release of Oxytocin

(2010) S. Gaetani et al.   JOURNAL OF NEUROSCIENCE

Oxytocin as feeding inhibitor: Maintaining homeostasis in consummatory behavior

(2010) Pawel K. Olszewski et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A Comparative Study of Fat Storage Quantitation in Nematode Caenorhabditis elegans Using Label and Label-Free Methods

(2010) Kelvin Yen et al.   PLoS One

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

(2009) Terence I. Moy et al.   ACS Chemical Biology

C. elegans Major Fats Are Stored in Vesicles Distinct from Lysosome-Related Organelles

(2009) Eyleen J. O'Rourke et al.   Cell Metabolism

Systemic regulation of starvation response in Caenorhabditis elegans

(2009) C. Kang et al.   GENES & DEVELOPMENT

Central administration of substance P inhibits feeding behavior in chicks

(2009) Tetsuya Tachibana et al.   HORMONES AND BEHAVIOR

Ontogeny and nutritional control of adipogenesis in zebrafish (Danio rerio)

(2009) Edward J. Flynn et al.   JOURNAL OF LIPID RESEARCH

A high throughput Nile red method for quantitative measurement of neutral lipids in microalgae

(2009) Wei Chen et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Simple Methods to Detect Triacylglycerol Biosynthesis in a Yeast-Based Recombinant System

(2009) Rodrigo M. P. Siloto et al.   LIPIDS

Predicting new molecular targets for known drugs

(2009) Michael J. Keiser et al.   NATURE

Quantifying biogenic bias in screening libraries

(2009) Jérôme Hert et al.   Nature Chemical Biology

The Influence of Bacterial Diet on Fat Storage in C. elegans

(2009) Kyleann K. Brooks et al.   PLoS One

Serotonin Regulates C. elegans Fat and Feeding through Independent Molecular Mechanisms

(2008) Supriya Srinivasan et al.   Cell Metabolism

Insulin, cGMP, and TGF-β Signals Regulate Food Intake and Quiescence in C. elegans: A Model for Satiety

(2008) Young-jai You et al.   Cell Metabolism

Neural and Molecular Dissection of a C. elegans Sensory Circuit that Regulates Fat and Feeding

(2008) Elisabeth R. Greer et al.   Cell Metabolism

A high throughput live transparent animal bioassay to identify non-toxic small molecules or genes that regulate vertebrate fat metabolism for obesity drug development

(2008) Kevin S Jones et al.   Nutrition & Metabolism