Editorial Material
Cell & Tissue Engineering
Maria-Eleni Lalioti, Jasmin Rettkowski, Nina Cabezas-Wallscheid
Summary: This study identified Hsf1 as a new target that helps maintain HSC fitness and protein homeostasis during both culture and aging.
Article
Engineering, Chemical
Arthur M. (Art) Dowell
Summary: The number of inputs and outputs to a SIF can affect PFD and SIL, with more inputs and outputs potentially leading to higher PFD and lower SIL. When it is challenging to achieve target PFD and SIL for a large processing unit, splitting the SIF into smaller, more manageable sections using layer of protection analysis principles can be a solution.
PROCESS SAFETY PROGRESS
(2022)
Editorial Material
Robotics
James Young
Summary: While human-like social robots are designed to support communication, they can also possess dangerously persuasive capabilities.
Article
Immunology
Gabriela Capurro, Ryan Maier, Jordan Tustin, Cindy G. Jardine, S. Michelle Driedger
Summary: A minority of Canadians are hesitant or refuse COVID-19 vaccines. Focus groups revealed that vaccine hesitancy is driven by perceptions of COVID-19 and vaccine risks, religious and conservative views, and distrust in government and science. Recommendations to improve vaccine uptake include emphasizing the benefits of vaccination, addressing community concerns, highlighting vaccine safety, and framing vaccination as a desirable behavior from a religious perspective.
Editorial Material
Oncology
Sangeetha Venugopal, Justin Taylor
Summary: In this article, Nguyen and colleagues discuss the increased risk of disseminated intravascular coagulation (DIC) in patients with KMT2Ar acute myeloid leukemia (AML) through a retrospective single-institution analysis. Venugopal and Taylor provide a perspective by comparing this study with other AML subtypes that are also at high risk of DIC and bleeding.
Article
Multidisciplinary Sciences
Xiaobo Yu, Xuecheng Zhang, Peng Zhao, Xiongbo Peng, Hong Chen, Andrea Bleckmann, Anastasiia Bazhenova, Ce Shi, Thomas Dresselhaus, Meng-xiang Sun
Summary: Animal egg cells secrete proteases to establish a fertilization envelope to prevent polyspermy, while plant egg cells secrete ECS1 and ECS2 endopeptidases to rapidly block the penetration of multiple pollen tubes into ovules after successful fertilization.
Article
Engineering, Manufacturing
Kaitlin M. Daniels, Leon Valdes
Summary: Non-profit organizations face challenges in accepting donations, including the pressure of rejecting unwanted donations that may impose operational costs. The study reveals that rejections impact donors' beliefs and future donations by reducing their confidence in success. Additionally, rejection has a more significant negative effect on donors' beliefs when a high effort is required for donation.
PRODUCTION AND OPERATIONS MANAGEMENT
(2021)
Editorial Material
Biochemistry & Molecular Biology
Michael Gross
Summary: After decades of warnings about the global spread of antibiotic resistance genes, it is becoming more and more threatening. The traditional strategy of semisynthetic modification of existing or natural antibiotics may not be able to keep up with the problem, leading to the proposal of entirely new strategies to combat this issue.
Editorial Material
Biochemistry & Molecular Biology
Theunis Piersma, Jorge S. Gutierrez
Summary: Recent studies have shown that migrating great snipes fly at high altitudes during the day and lower at night. This difference in flight patterns has left researchers puzzled, raising more questions about the behavior of these birds.
News Item
Biochemistry & Molecular Biology
Jon M. Fukuto
Summary: Hydropersulfides have been identified as potent inhibitors of membrane damage and destruction, with the potential to regulate ferroptosis.
NATURE CHEMICAL BIOLOGY
(2023)
Article
Psychiatry
Silvana Galderisi
Summary: My research focuses on unmet needs in caring for people with schizophrenia, particularly negative symptoms which have a significant impact on the disease outcome and are not effectively addressed by existing treatments. In this commentary, I summarize the trajectory of my research, starting with my attempts to define the role of the dorsolateral prefrontal cortex in the pathogenesis of negative symptoms. I then discuss the importance of considering the heterogeneity and complexity of the construct in order to make progress in researching schizophrenia negative symptoms.
PSYCHIATRY RESEARCH
(2023)
Article
Multidisciplinary Sciences
Darrin T. Schultz, Steven H. D. Haddock, Jessen V. Bredeson, Richard E. Green, Oleg Simakov, Daniel S. Rokhsar
Summary: This article examines whether sponges or ctenophores are the sister group to all other animals. The research found that ctenophores share chromosome rearrangement features with invertebrates and cnidarians, while sponges have different chromosome rearrangements. These findings provide a new framework for resolving deep phylogenetic problems.
Article
Entomology
Jeferson Pedrosa dos Santos, Bruno Gusmao Vieira, Rafael Carvalho da Silva, Fabio Santos do Nascimento
Summary: Social insects have organized task execution ability through a complex information transfer system. Competition decisions are made based on costs and benefits, with food quality being the most important factor for Plebeia droryana foragers. Different responses were observed in P. droryana towards the chemical and visual cues of Trigona spinipes.
Article
Medicine, General & Internal
Catrin Mann, Nadine Conradi, Elisabeth Neuhaus, Juergen Konczalla, Thomas M. Freiman, Andrea Spyrantis, Katharina Weber, Patrick Harter, Felix Rosenow, Adam Strzelczyk, Susanne Schubert-Bast
Summary: This study analyzed a cohort of patients with low-grade epilepsy-associated neuroepithelial tumors (LEAT) who underwent resective epilepsy surgery at the Epilepsy Center Frankfurt Rhine-Main, Germany. The findings showed that hippocampus and amygdala resection were associated with seizure control in temporal lobe epilepsy. Patients with preoperative cognitive deficits had a longer duration of epilepsy, while focal to bilateral tonic-clonic seizures and younger age at onset were associated with a higher likelihood of postoperative cognitive deficits.
JOURNAL OF CLINICAL MEDICINE
(2022)
News Item
Multidisciplinary Sciences
Dyani Lewis
Summary: The strategy is effective in reducing sexually transmitted infections but may lead to an increase in antimicrobial resistance.
