In silico molecular cytogenetics: a bioinformatic approach to prioritization of candidate genes and copy number variations for basic and clinical genome research

Parental Somatic Mosaicism Is Underrecognized and Influences Recurrence Risk of Genomic Disorders

(2014) Ian M. Campbell et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cytometry in the brain: studying differentiation to diagnostic applications in brain disease and regeneration therapy

(2014) H. Ulrich et al.   CELL PROLIFERATION

Aneuploidy: implications for protein homeostasis and disease

(2014) A. B. Oromendia et al.   Disease Models & Mechanisms

Prioritization of neurodevelopmental disease genes by discovery of new mutations

(2014) Alexander Hoischen et al.   NATURE NEUROSCIENCE

Harnessing Gene Expression Networks to Prioritize Candidate Epileptic Encephalopathy Genes

(2014) Karen L. Oliver et al.   PLoS One

Aurea Mediocritas: The Importance of a Balanced Genome

(2014) G. Varetti et al.   Cold Spring Harbor Perspectives in Biology

Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromes

(2014) Wangzhi Li et al.   Epigenomics

Cytogenomic mapping and bioinformatic mining reveal interacting brain expressed genes for intellectual disability

(2014) Fang Xu et al.   Molecular Cytogenetics

X chromosome aneuploidy in the Alzheimer’s disease brain

(2014) Yuri B Yurov et al.   Molecular Cytogenetics

Integrated Analysis of Transcriptomic and Proteomic Data

(2013) Saad Haider et al.   CURRENT GENOMICS

Genotype to phenotype via network analysis

(2013) Hannah Carter et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Somatic Cell Genomics of Brain Disorders: A New Opportunity to Clarify Genetic-Environmental Interactions

(2013) I.Y. Iourov et al.   CYTOGENETIC AND GENOME RESEARCH

Increased genome instability in human DNA segments with self-chains: homology-induced structural variations via replicative mechanisms

(2013) Weichen Zhou et al.   HUMAN MOLECULAR GENETICS

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Elevated Tolerance to Aneuploidy in Cancer Cells: Estimating the Fitness Effects of Chromosome Number Alterations by In Silico Modelling of Somatic Genome Evolution

(2013) Anders Valind et al.   PLoS One

An Algorithm for Network-Based Gene Prioritization That Encodes Knowledge Both in Nodes and in Links

(2013) Chad Kimmel et al.   PLoS One

The genomically mosaic brain: Aneuploidy and more in neural diversity and disease

(2013) Diane M. Bushman et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Xq28 (MECP2) microdeletions are common in mutation-negative females with Rett syndrome and cause mild subtypes of the disease

(2013) Ivan Y Iourov et al.   Molecular Cytogenetics

Bioinformatic Tools Identify Chromosome-Specific DNA Probes and Facilitate Risk Assessment by Detecting Aneusomies in Extra-embryonic Tissues

(2012) Hui Zeng et al.   CURRENT GENOMICS

Identification of Pharmacological Targets in Amyotrophic Lateral Sclerosis Through Genomic Analysis of Deregulated Genes and Pathways

(2012) Sabrina Paratore et al.   CURRENT GENOMICS

Single Cell Genomics of the Brain: Focus on Neuronal Diversity and Neuropsychiatric Diseases

(2012) Ivan Y Iourov et al.   CURRENT GENOMICS

Bioinformatics Tools Allow Targeted Selection of Chromosome Enumeration Probes and Aneuploidy Detection

(2012) Benjamin O’Brien et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Computational tools for prioritizing candidate genes: boosting disease gene discovery

(2012) Yves Moreau et al.   NATURE REVIEWS GENETICS

The DNA Replication Stress Hypothesis of Alzheimer’s Disease

(2012) Yuri B. Yurov et al.   TheScientificWorldJOURNAL

Implications of aneuploidy for stem cell biology and brain therapeutics

(2012) Sylvie Devalle et al.   Frontiers in Cellular Neuroscience

Molecular karyotyping by array CGH in a Russian cohort of children with intellectual disability, autism, epilepsy and congenital anomalies

(2012) Ivan Y Iourov et al.   Molecular Cytogenetics

Interactome Networks and Human Disease

(2011) Marc Vidal et al.   CELL

Decoding the genome beyond sequencing: The new phase of genomic research

(2011) Henry H.Q. Heng et al.   GENOMICS

In Silico Gene Prioritization by Integrating Multiple Data Sources

(2011) Yixuan Chen et al.   PLoS One

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Somatic Genome Variations in Health and Disease

(2010) I. Iourov et al.   CURRENT GENOMICS

Molecular Cytogenetic Diagnosis and Somatic Genome Variations

(2010) S. Vorsanova et al.   CURRENT GENOMICS

Identification of candidate genes of autism on the basis of molecular cytogenetic and in silico studies of the genome organization of chromosomal regions involved in unbalanced rearrangements

(2010) I. Yu. Iourov et al.   RUSSIAN JOURNAL OF GENETICS

Human interphase chromosomes: a review of available molecular cytogenetic technologies

(2010) Svetlana G Vorsanova et al.   Molecular Cytogenetics

Accurate Distinction of Pathogenic from Benign CNVs in Mental Retardation

(2010) Jayne Y. Hehir-Kwa et al.   PLoS Computational Biology

Disease candidate gene identification and prioritization using protein interaction networks

(2009) Jing Chen et al.   BMC BIOINFORMATICS

Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain

(2009) Ivan Y. Iourov et al.   HUMAN MOLECULAR GENETICS

Aneuploidy in the normal, Alzheimer's disease and ataxia-telangiectasia brain: Differential expression and pathological meaning

(2009) Ivan Y. Iourov et al.   NEUROBIOLOGY OF DISEASE

Aneuploidy: From a Physiological Mechanism of Variance to Down Syndrome

(2009) Mara Dierssen et al.   PHYSIOLOGICAL REVIEWS

GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny

(2009) Yuri B Yurov et al.   Molecular Cytogenetics

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

(2009) Chunlei Wu et al.   GENOME BIOLOGY

Walking the Interactome for Prioritization of Candidate Disease Genes

(2008) Sebastian Köhler et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Molecular Cytogenetics and Cytogenomics of Brain Diseases

(2008) I. Iourov et al.   CURRENT GENOMICS

Network-based prediction of human tissue-specific metabolism

(2008) Tomer Shlomi et al.   NATURE BIOTECHNOLOGY

Partial monosomy 7q34-qter and 21pter-q22.13 due to cryptic unbalanced translocation t(7;21) but not monosomy of the whole chromosome 21: a case report plus review of the literature

(2008) Svetlana G Vorsanova et al.   Molecular Cytogenetics

Chromosomal mosaicism goes global

(2008) Ivan Y Iourov et al.   Molecular Cytogenetics

The schizophrenia brain exhibits low-level aneuploidy involving chromosome 1

(2007) Yuri B. Yurov et al.   SCHIZOPHRENIA RESEARCH