期刊
JOURNAL OF SAUDI CHEMICAL SOCIETY
卷 15, 期 4, 页码 345-350出版社
ELSEVIER
DOI: 10.1016/j.jscs.2011.04.010
关键词
Flavonoids; Sisymbrium irio; Antioxidant activities; Apigenin; Apigenin-7-di-glucoside
资金
- Deanship of Scientific Research at King Saud University [RGP-VPP-060]
Ten flavonoids were isolated for the first time from the aerial parts of Sisymbrium irio L. grown in Saudia Arabia, using chromatographic methods, and identified as apigenin, apigenin-7-galactoside, apigenin-7-O-beta-D-glucoside, luteolin-7-O-glucoside, apigenin-7-di-glucoside 5, apigenin-7-O-(6 '' acetyl) glucoside, apigenin-7-O-gluco(6 ''-1''') rhamnoside, apigenin-7-O-gluco (6 ''-1''')rhamnoside-5-methoxide, kampferol and kampferol-3-xyloside-7-galactoside. The median lethal dose of the extract was determined in mice and found to be greater than 5000 mg/kg body weight, suggesting that this plant is non-toxic. Antioxidant activities were assessed for all extracts and fractions (total, ether, chloroform, ethyl acetate and butanol) and isolated compounds, and showed variable antioxidant activity, with apigenin-7-O-galactoside being the most potent. (C) 2011 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.
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