An integrated transcriptome and expressed variant analysis of sepsis survival and death

Integrative “Omic” Analysis of Experimental Bacteremia Identifies a Metabolic Signature That Distinguishes Human Sepsis from Systemic Inflammatory Response Syndromes

(2014) Raymond J. Langley et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hospital Deaths in Patients With Sepsis From 2 Independent Cohorts

(2014) Vincent Liu et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Patterns of Gene Expression in Peripheral Blood Mononuclear Cells and Outcomes from Patients with Sepsis Secondary to Community Acquired Pneumonia

(2014) Patricia Severino et al.   PLoS One

Metabolomic Derangements Are Associated with Mortality in Critically Ill Adult Patients

(2014) Angela J. Rogers et al.   PLoS One

Metabolic Profiling of Serum Samples by 1H Nuclear Magnetic Resonance Spectroscopy as a Potential Diagnostic Approach for Septic Shock*

(2013) Beata Mickiewicz et al.   CRITICAL CARE MEDICINE

Biomarkers in sepsis

(2013) Mervyn Singer   CURRENT OPINION IN PULMONARY MEDICINE

Proteomics Reveals Age-Related Differences in the Host Immune Response to Sepsis

(2013) Zhiyun Cao et al.   JOURNAL OF PROTEOME RESEARCH

Gene Expression-Based Classifiers Identify Staphylococcus aureus Infection in Mice and Humans

(2013) Sun Hee Ahn et al.   PLoS One

S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB1

(2013) Jean-Christophe Simard et al.   PLoS One

The State of Infectious Diseases Clinical Trials: A Systematic Review of ClinicalTrials.gov

(2013) Neela D. Goswami et al.   PLoS One

Frequency and Pattern of Heteroplasmy in the Complete Human Mitochondrial Genome

(2013) Amanda Ramos et al.   PLoS One

Genome-Wide Sequencing of Cellular microRNAs Identifies a Combinatorial Expression Signature Diagnostic of Sepsis

(2013) Yuqian Ma et al.   PLoS One

An Integrated Clinico-Metabolomic Model Improves Prediction of Death in Sepsis

(2013) R. J. Langley et al.   Science Translational Medicine

Temporal Metabolic Profiling of Plasma During Endotoxemia in Humans

(2013) Kubra Kamisoglu et al.   SHOCK

Characterization and Identification of Novel Serum MicroRNAs in Sepsis Patients With Different Outcomes

(2013) Hui-juan Wang et al.   SHOCK

Mitochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease

(2013) D. C. Wallace et al.   Cold Spring Harbor Perspectives in Biology

Spurious Inferences about Long-Term Outcomes

(2012) Theodore J. Iwashyna et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The Emerging Importance of Autophagy in Pulmonary Diseases

(2012) Kenji Mizumura et al.   CHEST

An integrated map of genetic variation from 1,092 human genomes

(2012)   NATURE

Serum MicroRNA Signatures Identified by Solexa Sequencing Predict Sepsis Patients’ Mortality: A Prospective Observational Study

(2012) Huijuan Wang et al.   PLoS One

Rapid Whole-Genome Sequencing for Genetic Disease Diagnosis in Neonatal Intensive Care Units

(2012) C. J. Saunders et al.   Science Translational Medicine

Comparison of Sepsis-Induced Transcriptomic Changes in a Murine Model to Clinical Blood Samples Identifies Common Response Patterns

(2012) Sandro Lambeck et al.   Frontiers in Microbiology

Nationwide Trends of Severe Sepsis in the 21st Century (2000–2007)

(2011) Gagan Kumar et al.   CHEST

Discriminative Value of Inflammatory Biomarkers for Suspected Sepsis

(2011) Ephraim L. Tsalik et al.   JOURNAL OF EMERGENCY MEDICINE

A framework for variation discovery and genotyping using next-generation DNA sequencing data

(2011) Mark A DePristo et al.   NATURE GENETICS

Disease Progression in Hemodynamically Stable Patients Presenting to the Emergency Department With Sepsis

(2010) Seth W. Glickman et al.   ACADEMIC EMERGENCY MEDICINE

Detecting Heteroplasmy from High-Throughput Sequencing of Complete Human Mitochondrial DNA Genomes

(2010) Mingkun Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Survival in Critical Illness Is Associated with Early Activation of Mitochondrial Biogenesis

(2010) Jane E. Carré et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor

(2010) William McLaren et al.   BIOINFORMATICS

Long-term mortality and quality of life in sepsis: A systematic review*

(2010) Bradford D. Winters et al.   CRITICAL CARE MEDICINE

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups

(2010) Anita Kloss-Brandstätter et al.   HUMAN MUTATION

Critical care and the global burden of critical illness in adults

(2010) Neill KJ Adhikari et al.   LANCET

Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

(2010) Sergio E. Baranzini et al.   NATURE

A human MAP kinase interactome

(2010) Sourav Bandyopadhyay et al.   NATURE METHODS

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum*

(2009) Hector R. Wong et al.   CRITICAL CARE MEDICINE

Gene-expression profiling of peripheral blood mononuclear cells in sepsis*

(2009) Benjamin M. P. Tang et al.   CRITICAL CARE MEDICINE

Multiplex PCR To Diagnose Bloodstream Infections in Patients Admitted from the Emergency Department with Sepsis

(2009) Ephraim L. Tsalik et al.   JOURNAL OF CLINICAL MICROBIOLOGY

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

Association of Mitochondrial Allele 4216C With Increased Risk for Complicated Sepsis and Death After Traumatic Injury

(2009) Ruben Gomez et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Methods for Detecting Associations with Rare Variants for Common Diseases: Application to Analysis of Sequence Data

(2008) Bingshan Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

RNA-Seq: a revolutionary tool for transcriptomics

(2008) Zhong Wang et al.   NATURE REVIEWS GENETICS

Genomic Convergence Analysis of Schizophrenia: mRNA Sequencing Reveals Altered Synaptic Vesicular Transport in Post-Mortem Cerebellum

(2008) Joann Mudge et al.   PLoS One

Transcriptome sequencing of malignant pleural mesothelioma tumors

(2008) D. J. Sugarbaker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA