Variants of uncertain significance in BRCA: a harbinger of ethical and policy issues to come?

Living laboratory: whole-genome sequencing as a learning healthcare enterprise

(2014) M. Angrist et al.   CLINICAL GENETICS

Clinically Relevant Variants - Identifying, Collecting, Interpreting, and Disseminating: The 2013 Annual Scientific Meeting of the Human Genome Variation Society

(2014) Christine M. Stanley et al.   HUMAN MUTATION

Molecular Findings Among Patients Referred for Clinical Whole-Exome Sequencing

(2014) Yaping Yang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Interpretation and Implications of Whole-Genome Sequencing

(2014) Frederick E. Dewey et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Application of Whole-Genome Sequencing

(2014) William Gregory Feero   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Clinical Evaluation of a Multiple-Gene Sequencing Panel for Hereditary Cancer Risk Assessment

(2014) Allison W. Kurian et al.   JOURNAL OF CLINICAL ONCOLOGY

Diagnostic Clinical Genome and Exome Sequencing

(2014) Leslie G. Biesecker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Variants of unknown significance in BRCA testing: impact on risk perception, worry, prevention and counseling

(2013) S. Richter et al.   ANNALS OF ONCOLOGY

Variants of uncertain significance inBRCAtesting: evaluation of surgical decisions, risk perception, and cancer distress

(2013) JO Culver et al.   CLINICAL GENETICS

A comprehensive laboratory-based program for classification of variants of uncertain significance in hereditary cancer genes

(2013) J.M. Eggington et al.   CLINICAL GENETICS

Recommendations for reporting results of diagnostic genetic testing (biochemical, cytogenetic and molecular genetic)

(2013) Mireille Claustres et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing

(2013) Robert C. Green et al.   GENETICS IN MEDICINE

Adoption Of Electronic Health Records Grows Rapidly, But Fewer Than Half Of US Hospitals Had At Least A Basic System In 2012

(2013) Catherine M. DesRoches et al.   HEALTH AFFAIRS

Multiplex Genetic Testing for Cancer Susceptibility: Out on the High Wire Without a Net?

(2013) Susan M. Domchek et al.   JOURNAL OF CLINICAL ONCOLOGY

Clinical Whole-Exome Sequencing for the Diagnosis of Mendelian Disorders

(2013) Yaping Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

BRCA1/2 Sequence Variants of Uncertain Significance: A Primer for Providers to Assist in Discussions and in Medical Management

(2013) N. M. Lindor et al.   ONCOLOGIST

Best ethical practices for clinicians and laboratories in the provision of noninvasive prenatal testing

(2013) M. A. Allyse et al.   PRENATAL DIAGNOSIS

Constructing narratives of heroism and villainy: case study of Myriad's BRACAnalysis® compared to Genentech's Herceptin®

(2013) A Baldwin et al.   Genome Medicine

Reflections on the Cost of "Low-Cost" Whole Genome Sequencing: Framing the Health Policy Debate

(2013) Timothy Caulfield et al.   PLOS BIOLOGY

Unclassified variants in BRCA genes: guidelines for interpretation

(2011) P. Radice et al.   ANNALS OF ONCOLOGY

Genetic testing and cancer risk management recommendations by physicians for at-risk relatives

(2011) Sharon E Plon et al.   GENETICS IN MEDICINE

ENIGMA-Evidence-based network for the interpretation of germline mutant alleles: An international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes

(2011) Amanda B. Spurdle et al.   HUMAN MUTATION

A review of a multifactorial probability-based model for classification of BRCA1 and BRCA2 variants of uncertain significance (VUS)

(2011) Noralane M. Lindor et al.   HUMAN MUTATION

The Coming Explosion in Genetic Testing — Is There a Duty to Recontact?

(2011) Reed E. Pyeritz   NEW ENGLAND JOURNAL OF MEDICINE

Variants of Uncertain Significance in Breast Cancer–Related Genes: Real-World Implications for a Clinical Conundrum. Part One: Clinical Genetics Recommendations

(2011) Susan Miller-Samuel et al.   SEMINARS IN ONCOLOGY

Myriad Genetics: In the eye of the policy storm

(2010) E Richard Gold et al.   GENETICS IN MEDICINE

A Progress Report On Electronic Health Records In U.S. Hospitals

(2010) Ashish K. Jha et al.   HEALTH AFFAIRS

Use of Electronic Health Records in U.S. Hospitals

(2009) Ashish K. Jha et al.   NEW ENGLAND JOURNAL OF MEDICINE

ACMG recommendations for standards for interpretation and reporting of sequence variations: Revisions 2007

(2008) C Sue Richards et al.   GENETICS IN MEDICINE

Assessing pathogenicity: overview of results from the IARC Unclassified Genetic Variants Working Group

(2008) Sean V. Tavtigian et al.   HUMAN MUTATION

Sequence variant classification and reporting: recommendations for improving the interpretation of cancer susceptibility genetic test results

(2008) Sharon E. Plon et al.   HUMAN MUTATION

BRCAGermline Mutations in Jewish Patients With Pancreatic Adenocarcinoma

(2008) Cristina R. Ferrone et al.   JOURNAL OF CLINICAL ONCOLOGY

Genetic Variants of Uncertain Significance: Flies in the Ointment

(2007) Susan Domchek et al.   JOURNAL OF CLINICAL ONCOLOGY