Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations
出版年份 2012 全文链接
标题
Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations
作者
关键词
-
出版物
Genome Medicine
Volume 4, Issue 4, Pages 30
出版商
Springer Nature
发表日期
2012-04-30
DOI
10.1186/gm329
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pharmacometabonomic Profiling as a Predictor of Toxicity in Patients with Inoperable Colorectal Cancer Treated with Capecitabine
- (2011) A. Backshall et al. CLINICAL CANCER RESEARCH
- Strategies for exome and genome sequence data analysis in disease-gene discovery projects
- (2011) PN Robinson et al. CLINICAL GENETICS
- A metabolomic and systems biology perspective on the brain of the Fragile X syndrome mouse model
- (2011) L. Davidovic et al. GENOME RESEARCH
- Genetic associations with lipoprotein subfractions provide information on their biological nature
- (2011) Ann-Kristin Petersen et al. HUMAN MOLECULAR GENETICS
- Mass Spectrometry Strategies in Metabolomics
- (2011) Zhentian Lei et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase
- (2011) Jean-Baptise Cazier et al. JOURNAL OF PROTEOME RESEARCH
- Detection of autosomal dominant polycystic kidney disease by NMR spectroscopic fingerprinting of urine
- (2011) Wolfram Gronwald et al. KIDNEY INTERNATIONAL
- Mapping copy number variation by population-scale genome sequencing
- (2011) Ryan E. Mills et al. NATURE
- Charting a course for genomic medicine from base pairs to bedside
- (2011) Eric D. Green et al. NATURE
- Human metabolic individuality in biomedical and pharmaceutical research
- (2011) Karsten Suhre et al. NATURE
- Enterotypes of the human gut microbiome
- (2011) Manimozhiyan Arumugam et al. NATURE
- A genome-wide association study of metabolic traits in human urine
- (2011) Karsten Suhre et al. NATURE GENETICS
- Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry
- (2011) Eric Chun Yong Chan et al. Nature Protocols
- Exome sequencing as a tool for Mendelian disease gene discovery
- (2011) Michael J. Bamshad et al. NATURE REVIEWS GENETICS
- NT5EMutations and Arterial Calcifications
- (2011) Cynthia St. Hilaire et al. NEW ENGLAND JOURNAL OF MEDICINE
- Genome-wide association studies and systems biology: together at last
- (2011) Mika Ala-Korpela et al. TRENDS IN GENETICS
- Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers
- (2011) Kirstin Mittelstrass et al. PLoS Genetics
- A Genome-Wide Metabolic QTL Analysis in Europeans Implicates Two Loci Shaped by Recent Positive Selection
- (2011) George Nicholson et al. PLoS Genetics
- Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans
- (2010) J H Winnike et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Making a definitive diagnosis: Successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease
- (2010) Elizabeth A Worthey et al. GENETICS IN MEDICINE
- Opening up the "Black Box": Metabolic phenotyping and metabolome-wide association studies in epidemiology
- (2010) Magda Bictash et al. JOURNAL OF CLINICAL EPIDEMIOLOGY
- Urinary Metabolic Phenotyping Differentiates Children with Autism from Their Unaffected Siblings and Age-Matched Controls
- (2010) Ivan K. S. Yap et al. JOURNAL OF PROTEOME RESEARCH
- Metabolome-Wide Association Study Identifies Multiple Biomarkers that Discriminate North and South Chinese Populations at Differing Risks of Cardiovascular Disease: INTERMAP Study
- (2010) Ivan K. S. Yap et al. JOURNAL OF PROTEOME RESEARCH
- Hundreds of variants clustered in genomic loci and biological pathways affect human height
- (2010) Hana Lango Allen et al. NATURE
- A map of human genome variation from population-scale sequencing
- (2010) Richard M. Durbin et al. NATURE
- A human gut microbial gene catalogue established by metagenomic sequencing
- (2010) Junjie Qin et al. NATURE
- Global metabolic profiling procedures for urine using UPLC–MS
- (2010) Elizabeth J Want et al. Nature Protocols
- Pharmacometabonomics as an effector for personalized medicine
- (2010) Jeremy K Nicholson et al. PHARMACOGENOMICS
- Exploring Disease through Metabolomics
- (2009) Nawaporn Vinayavekhin et al. ACS Chemical Biology
- Statistical Recoupling Prior to Significance Testing in Nuclear Magnetic Resonance Based Metabonomics
- (2009) Benjamin J. Blaise et al. ANALYTICAL CHEMISTRY
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Next-Generation Sequencing: A New Revolution in Molecular Diagnostics?
- (2009) E. P. Diamandis CLINICAL CHEMISTRY
- The ClinSeq Project: Piloting large-scale genome sequencing for research in genomic medicine
- (2009) L. G. Biesecker et al. GENOME RESEARCH
- Top-Down Systems Biology Modeling of Host Metabotype−Microbiome Associations in Obese Rodents
- (2009) Alison Waldram et al. JOURNAL OF PROTEOME RESEARCH
- Metabonomics in Ulcerative Colitis: Diagnostics, Biomarker Identification, And Insight into the Pathophysiology
- (2009) Jacob T. Bjerrum et al. JOURNAL OF PROTEOME RESEARCH
- Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
- (2009) Arun Sreekumar et al. NATURE
- Exome sequencing identifies the cause of a mendelian disorder
- (2009) Sarah B Ng et al. NATURE GENETICS
- A genome-wide perspective of genetic variation in human metabolism
- (2009) Thomas Illig et al. NATURE GENETICS
- Guanidinoacetate methyltransferase (GAMT) deficiency diagnosed by proton NMR spectroscopy of body fluids
- (2009) Udo F. H. Engelke et al. NMR IN BIOMEDICINE
- Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
- (2009) T. A. Clayton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- XCMS2: Processing Tandem Mass Spectrometry Data for Metabolite Identification and Structural Characterization
- (2008) H. P. Benton et al. ANALYTICAL CHEMISTRY
- An Invitation to the Marriage of Metagenomics and Metabolomics
- (2008) Peter J. Turnbaugh et al. CELL
- Human QTL linkage mapping
- (2008) Laura Almasy et al. GENETICA
- The Metabolome-Wide Association Study: A New Look at Human Disease Risk Factors
- (2008) Jeremy K. Nicholson et al. JOURNAL OF PROTEOME RESEARCH
- Human metabolic phenotype diversity and its association with diet and blood pressure
- (2008) Elaine Holmes et al. NATURE
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges
- (2008) Mark I. McCarthy et al. NATURE REVIEWS GENETICS
- RNA-Seq: a revolutionary tool for transcriptomics
- (2008) Zhong Wang et al. NATURE REVIEWS GENETICS
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
- (2008) Christian Gieger et al. PLoS Genetics
- NMR spectroscopy of aminoacylase 1 deficiency, a novel inborn error of metabolism
- (2007) Udo F. H. Engelke et al. NMR IN BIOMEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started