DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma

Down-Regulation of Methylthioadenosine Phosphorylase ( MTAP ) Induces Progression of Hepatocellular Carcinoma via Accumulation of 5′-Deoxy-5′-Methylthioadenosine (MTA)

(2011) Georgi Kirovski et al.   AMERICAN JOURNAL OF PATHOLOGY

Perspectives on Epigenetics and Its Relevance to Adverse Drug Reactions

(2011) M Kacevska et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Strategies for hepatocellular carcinoma therapy and diagnostics: Lessons learned from high throughput and profiling approaches

(2011) Kai Breuhahn et al.   HEPATOLOGY

DNA Methylation of the First Exon Is Tightly Linked to Transcriptional Silencing

(2011) Fabienne Brenet et al.   PLoS One

Aberrant CpG island hypermethylation in dysplastic nodules and early HCC of hepatitis B virus-related human multistep hepatocarcinogenesis

(2010) Tae-Hee Um et al.   JOURNAL OF HEPATOLOGY

Aberrant DNA methylation distinguishes hepatocellular carcinoma associated with HBV and HCV infection and alcohol intake

(2010) Marie-Pierre Lambert et al.   JOURNAL OF HEPATOLOGY

Organic Cation Transporters Modulate the Uptake and Cytotoxicity of Picoplatin, a Third-Generation Platinum Analogue

(2010) Swati S. More et al.   MOLECULAR CANCER THERAPEUTICS

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

GLUT1 Expression Is Increased in Hepatocellular Carcinoma and Promotes Tumorigenesis

(2009) Thomas Amann et al.   AMERICAN JOURNAL OF PATHOLOGY

Aberrant DNA methylation profile of hepatocellular carcinoma and surgically resected margin

(2009) Cheng Lou et al.   CANCER SCIENCE

Human copper transporters: mechanism, role in human diseases and therapeutic potential

(2009) Arnab Gupta et al.   Future Medicinal Chemistry

Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

(2009) Anne T. Nies et al.   HEPATOLOGY

Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma

(2009) Toyoki Moribe et al.   INTERNATIONAL JOURNAL OF CANCER

N-Myc Downstream-Regulated Gene 4 ( NDRG4 ): A Candidate Tumor Suppressor Gene and Potential Biomarker for Colorectal Cancer

(2009) Veerle Melotte et al.   JNCI-Journal of the National Cancer Institute

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas

(2008) Wentao Gao et al.   CARCINOGENESIS

EpCAM-Positive Hepatocellular Carcinoma Cells Are Tumor-Initiating Cells With Stem/Progenitor Cell Features

(2008) Taro Yamashita et al.   GASTROENTEROLOGY

Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation

(2008) Lijian Hui et al.   JOURNAL OF CLINICAL INVESTIGATION

DNA Methylation Markers and Early Recurrence in Stage I Lung Cancer

(2008) Malcolm V. Brock et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE

Cytosine methylation profiling of cancer cell lines

(2008) M. Ehrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organic cation transporters

(2008) G. Ciarimboli   XENOBIOTICA