Recombineering strategies for developing next generation BAC transgenic tools for optogenetics and beyond

Optogenetic insights into striatal function and behavior

(2013) Jeffrey D. Lenz et al.   BEHAVIOURAL BRAIN RESEARCH

ChAT-ChR2-EYFP Mice Have Enhanced Motor Endurance But Show Deficits in Attention and Several Additional Cognitive Domains

(2013) B. Kolisnyk et al.   JOURNAL OF NEUROSCIENCE

Concurrent activation of striatal direct and indirect pathways during action initiation

(2013) Guohong Cui et al.   NATURE

Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use

(2013) Roland Bock et al.   NATURE NEUROSCIENCE

A causal link between prediction errors, dopamine neurons and learning

(2013) Elizabeth E Steinberg et al.   NATURE NEUROSCIENCE

A Unique Population of Ventral Tegmental Area Neurons Inhibits the Lateral Habenula to Promote Reward

(2013) Alice M. Stamatakis et al.   NEURON

A Gαs DREADD Mouse for Selective Modulation of cAMP Production in Striatopallidal Neurons

(2013) Martilias S Farrell et al.   NEUROPSYCHOPHARMACOLOGY

Optogenetic dissection reveals multiple rhythmogenic modules underlying locomotion

(2013) M. Hagglund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic Insights into Social Behavior Function

(2012) Ofer Yizhar   BIOLOGICAL PSYCHIATRY

Optogenetic dissection of neural circuits underlying emotional valence and motivated behaviors

(2012) Edward H. Nieh et al.   BRAIN RESEARCH

Strain-Specific Regulation of Striatal Phenotype in Drd2-eGFP BAC Transgenic Mice

(2012) C. S. Chan et al.   JOURNAL OF NEUROSCIENCE

A Comparison of Striatal-Dependent Behaviors in Wild-Type and Hemizygous Drd1a and Drd2 BAC Transgenic Mice

(2012) A. B. Nelson et al.   JOURNAL OF NEUROSCIENCE

Optogenetic Activation of Basal Forebrain Cholinergic Neurons Modulates Neuronal Excitability and Sensory Responses in the Main Olfactory Bulb

(2012) M. Ma et al.   JOURNAL OF NEUROSCIENCE

A Cre-Dependent GCaMP3 Reporter Mouse for Neuronal Imaging In Vivo

(2012) H. A. Zariwala et al.   JOURNAL OF NEUROSCIENCE

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

(2012) Dipesh Chaudhury et al.   NATURE

A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing

(2012) Linda Madisen et al.   NATURE NEUROSCIENCE

Transient stimulation of distinct subpopulations of striatal neurons mimics changes in action value

(2012) Lung-Hao Tai et al.   NATURE NEUROSCIENCE

Optogenetic investigation of neural circuits underlying brain disease in animal models

(2012) Kay M. Tye et al.   NATURE REVIEWS NEUROSCIENCE

GABA Neurons of the VTA Drive Conditioned Place Aversion

(2012) Kelly R. Tan et al.   NEURON

Novel recombinant adeno-associated viruses for Cre activated and inactivated transgene expression in neurons

(2012) Arpiar Saunders et al.   Frontiers in Neural Circuits

Dopamine-Dependent Long-Term Depression Is Expressed in Striatal Spiny Neurons of Both Direct and Indirect Pathways: Implications for Parkinson's Disease

(2011) V. Bagetta et al.   JOURNAL OF NEUROSCIENCE

Dopamine D2 Receptor Overexpression Alters Behavior and Physiology in Drd2-EGFP Mice

(2011) P. F. Kramer et al.   JOURNAL OF NEUROSCIENCE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

(2011) Shengli Zhao et al.   NATURE METHODS

AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training

(2011) Yexica Aponte et al.   NATURE NEUROSCIENCE

Selective optical drive of thalamic reticular nucleus generates thalamic bursts and cortical spindles

(2011) Michael M Halassa et al.   NATURE NEUROSCIENCE

Habenula “Cholinergic” Neurons Corelease Glutamate and Acetylcholine and Activate Postsynaptic Neurons via Distinct Transmission Modes

(2011) Jing Ren et al.   NEURON

Recombinase-Driver Rat Lines: Tools, Techniques, and Optogenetic Application to Dopamine-Mediated Reinforcement

(2011) Ilana B. Witten et al.   NEURON

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Site-specific integrase-mediated transgenesis in mice via pronuclear injection

(2011) B. Tasic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes

(2010) Hsiao-Tuan Chao et al.   NATURE

Activation of groups of excitatory neurons in the mammalian spinal cord or hindbrain evokes locomotion

(2010) Martin Hägglund et al.   NATURE NEUROSCIENCE

BAC TG-EMBED: one-step method for high-level, copy-number-dependent, position-independent transgene expression

(2010) Qian Bian et al.   NUCLEIC ACIDS RESEARCH

Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression

(2010) Masato Ohtsuka et al.   NUCLEIC ACIDS RESEARCH

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

(2010) I. B. Witten et al.   SCIENCE

The subcellular organization of neocortical excitatory connections

(2009) Leopoldo Petreanu et al.   NATURE

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

(2009) Jessica A. Cardin et al.   NATURE

Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

(2009) Juan E Belforte et al.   NATURE NEUROSCIENCE

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL

A Translational Profiling Approach for the Molecular Characterization of CNS Cell Types

(2008) Myriam Heiman et al.   CELL

A FLEX Switch Targets Channelrhodopsin-2 to Multiple Cell Types for Imaging and Long-Range Circuit Mapping

(2008) D. Atasoy et al.   JOURNAL OF NEUROSCIENCE