Early life stress and serotonin transporter gene variation interact to affect the transcription of the glucocorticoid and mineralocorticoid receptors, and the co-chaperone FKBP5, in the adult rat brain

Evidence supporting the match/mismatch hypothesis of psychiatric disorders

(2014) Sara Santarelli et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Early life adversity and serotonin transporter gene variation interact at the level of the adrenal gland to affect the adult hypothalamo-pituitary-adrenal axis

(2014) R H A van der Doelen et al.   Translational Psychiatry

Childhood Maltreatment and Psychopathology: A Case for Ecophenotypic Variants as Clinically and Neurobiologically Distinct Subtypes

(2013) Martin H. Teicher et al.   AMERICAN JOURNAL OF PSYCHIATRY

Role of Prefrontal Cortex Glucocorticoid Receptors in Stress and Emotion

(2013) Jessica M. McKlveen et al.   BIOLOGICAL PSYCHIATRY

Glucocorticoid actions on synapses, circuits, and behavior: Implications for the energetics of stress

(2013) Brent Myers et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Chronic Stress-Induced Alterations of Dendritic Spine Subtypes Predict Functional Decrements in an Hypothalamo-Pituitary-Adrenal-Inhibitory Prefrontal Circuit

(2013) J. J. Radley et al.   JOURNAL OF NEUROSCIENCE

Adaptive fitness; early life adversity improves adult stress coping in heterozygous serotonin transporter knockout rats

(2013) R H A van der Doelen et al.   MOLECULAR PSYCHIATRY

Diverging neural pathways assemble a behavioural state from separable features in anxiety

(2013) Sung-Yon Kim et al.   NATURE

Neurobiological effects of neonatal maternal separation and post-weaning environmental enrichment

(2012) Ana Laura Vivinetto et al.   BEHAVIOURAL BRAIN RESEARCH

Glucocorticoid and mineralocorticoid receptor expression in the human hippocampus in major depressive disorder

(2012) Adriana Medina et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Behavioural therapy based on distraction alleviates impaired fear extinction in male serotonin transporter knockout rats

(2012) Lourens Nonkes et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Glucocorticoid Receptor and FKBP5 Expression Is Altered Following Exposure to Chronic Stress: Modulation by Antidepressant Treatment

(2012) Gianluigi Guidotti et al.   NEUROPSYCHOPHARMACOLOGY

Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity

(2012) Nikolaos P. Daskalakis et al.   PHYSIOLOGY & BEHAVIOR

The serotonin transporter gene and functional and pathological adaptation to environmental variation across the life span

(2012) Judith R. Homberg et al.   PROGRESS IN NEUROBIOLOGY

Stress induced hippocampal mineralocorticoid and estrogen receptor β gene expression and long-term potentiation in male adult rats is sensitive to early-life stress experience

(2012) Han Wang et al.   PSYCHONEUROENDOCRINOLOGY

Aberrant stress hormone receptor balance in the human prefrontal cortex and hypothalamic paraventricular nucleus of depressed patients

(2012) Xin-Rui Qi et al.   PSYCHONEUROENDOCRINOLOGY

The Serotonin Transporter Promoter Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited

(2011) Katja Karg et al.   ARCHIVES OF GENERAL PSYCHIATRY

Serotonin transporter genotype x construction stress interaction in rats

(2011) Pieter Schipper et al.   BEHAVIOURAL BRAIN RESEARCH

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress

(2011) Jakob Hartmann et al.   NEUROPHARMACOLOGY

Membrane Mineralocorticoid but not Glucocorticoid Receptors of the Dorsal Hippocampus Mediate the Rapid Effects of Corticosterone on Memory Retrieval

(2011) Rodolphe Dorey et al.   NEUROPSYCHOPHARMACOLOGY

Mismatch or cumulative stress: Toward an integrated hypothesis of programming effects

(2011) Esther Nederhof et al.   PHYSIOLOGY & BEHAVIOR

Social Defeat: Impact on Fear Extinction and Amygdala-Prefrontal Cortical Theta Synchrony in 5-HTT Deficient Mice

(2011) Venu Narayanan et al.   PLoS One

A common and functional mineralocorticoid receptor haplotype enhances optimism and protects against depression in females

(2011) M D Klok et al.   Translational Psychiatry

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

(2010) Avshalom Caspi et al.   AMERICAN JOURNAL OF PSYCHIATRY

Prefrontal control of fear: more than just extinction

(2010) Francisco Sotres-Bayon et al.   CURRENT OPINION IN NEUROBIOLOGY

Gender-Dependent Effects of Early Maternal Separation and Variable Chronic Stress on Vasopressinergic Activity and Glucocorticoid Receptor Expression in Adult Rats

(2010) G.M. Renard et al.   DEVELOPMENTAL NEUROSCIENCE

Decreased expression of mineralocorticoid receptor mRNA and its splice variants in postmortem brain regions of patients with major depressive disorder

(2010) Melanie D. Klok et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?

(2010) Michael S. Fanselow et al.   NEURON

Status of Glucocorticoid Alterations in Post-traumatic Stress Disorder

(2009) Rachel Yehuda   Annals of the New York Academy of Sciences

Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression

(2009) Neil Risch et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Corticosteroids Operate as a Switch between Memory Systems

(2009) Lars Schwabe et al.   JOURNAL OF COGNITIVE NEUROSCIENCE

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Neural regulation of endocrine and autonomic stress responses

(2009) Yvonne M. Ulrich-Lai et al.   NATURE REVIEWS NEUROSCIENCE

Conserved role for the serotonin transporter gene in rat and mouse neurobehavioral endophenotypes

(2009) A.V. Kalueff et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

(2009) Elisabeth B. Binder   PSYCHONEUROENDOCRINOLOGY

Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment

(2009) Jayanthi Maniam et al.   PSYCHONEUROENDOCRINOLOGY

The significance of glucocorticoid pulsatility

(2008) Stafford L. Lightman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

A History of Corticosterone Exposure Regulates Fear Extinction and Cortical NR2B, GluR2/3 and BDNF

(2008) Shannon L Gourley et al.   NEUROPSYCHOPHARMACOLOGY

Housekeeping genes revisited: Different expressions depending on gender, brain area and stressor

(2008) N.M. Derks et al.   NEUROSCIENCE

A study in male and female 5-HT transporter knockout rats: An animal model for anxiety and depression disorders

(2008) J.D.A. Olivier et al.   NEUROSCIENCE

Fundamental aspects of the impact of glucocorticoids on the (immature) brain

(2008) Danielle L. Champagne et al.   Seminars in Fetal & Neonatal Medicine

Identifying Molecular Substrates in a Mouse Model of the Serotonin Transporter × Environment Risk Factor for Anxiety and Depression

(2007) Valeria Carola et al.   BIOLOGICAL PSYCHIATRY