Alpha-1 antitrypsin and liver disease: mechanisms of injury and novel interventions

Oxidative stress contributes to liver damage in a murine model of alpha-1-antitrypsin deficiency

(2012) Nancy Y Marcus et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Sustained miRNA-mediated Knockdown of Mutant AAT With Simultaneous Augmentation of Wild-type AAT Has Minimal Effect on Global Liver miRNA Profiles

(2012) Christian Mueller et al.   MOLECULAR THERAPY

Diagnosis and Management of Patients With α1-Antitrypsin (A1AT) Deficiency

(2011) David R. Nelson et al.   Clinical Gastroenterology and Hepatology

Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model

(2010) Shalesh Kaushal et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Liver Disease Associated with ZZ α1-Antitrypsin Deficiency and Ursodeoxycholic Acid Therapy in Children

(2010) Panayotis Lykavieris et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

An Autophagy-Enhancing Drug Promotes Degradation of Mutant  1-Antitrypsin Z and Reduces Hepatic Fibrosis

(2010) T. Hidvegi et al.   SCIENCE

Single nucleotide polymorphism-mediated translational suppression of endoplasmic reticulum mannosidase I modifies the onset of end-stage liver disease in alpha1-antitrypsin deficiency

(2009) Shujuan Pan et al.   HEPATOLOGY