Article
Urology & Nephrology
Takuhiro Moromizato, Kentaro Kohagura, Kiyoyuki Tokuyama, Yoshiki Shiohira, Shigeki Toma, Hajime Uehara, Hisatomi Arima, Shinichiro Ueda, Kunitoshi Iseki
Summary: In chronic hemodialysis patients, diabetes mellitus, history of coronary intervention, and hypoalbuminemia were significant risk factors for mortality during the entire follow-up period. Different risk factors were identified for mortality during early follow-up period (<= 3 years) compared to those who survived for longer than 3 years.
AMERICAN JOURNAL OF NEPHROLOGY
(2021)
Article
Medicine, General & Internal
Archana Sharma-Oates, Dawit T. Zemedikun, Kanta Kumar, John A. Reynolds, Avinash Jain, Karim Raza, John A. Williams, Laura Bravo, Victor Roth Cardoso, Georgios Gkoutos, Krishnarajah Nirantharakumar, Janet M. Lord
Summary: Individuals from non-White ethnic groups in the UK were diagnosed with common IMDs at an earlier age than their White counterparts.
Article
Cardiac & Cardiovascular Systems
Zhengbao Zhu, Fu-Rong Li, Yiming Jia, Yang Li, Daoxia Guo, Jingsi Chen, Haili Tian, Jing Yang, Huan-Huan Yang, Li-Hua Chen, Kaixin Zhang, Pinni Yang, Lulu Sun, Mengyao Shi, Yonghong Zhang, Li-Qiang Qin, Guo-Chong Chen
Summary: This study found that a combined healthy lifestyle is associated with the incidence of heart failure, regardless of metabolic or genetic risk status.
CIRCULATION-HEART FAILURE
(2022)
Article
Clinical Neurology
Naaheed Mukadam, Louise Marston, Gemma Lewis, Rohini Mathur, Greta Rait, Gill Livingston
Summary: This study investigated the incidence of diagnosed dementia and its association with age at diagnosis and survival afterward among the three largest ethnic groups in the UK. The findings showed that Black people had a higher incidence of dementia, while South Asian and Black people were diagnosed and died at a younger age compared to White individuals. Therefore, targeted prevention and care strategies should be prioritized and tailored to these ethnic groups.
ALZHEIMERS & DEMENTIA
(2023)
Article
Clinical Neurology
Seung-Jae Lee, Seok Yoon, Yoon-Jong Bae, Cheryl D. Bushnell, Hyung Jun Kim, Dongwoo Kang
Summary: The study demonstrates the associations of migraine with cardio-cerebrovascular diseases, with stronger associations in females.
JOURNAL OF CLINICAL NEUROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Hossain Syed Azfar, Kenesh O. Dzhusupov, Hans Orru, Steven Nordin, Maria Nordin, Kati Orru
Summary: This study in Kyrgyzstan found significant differences in the distribution of CVD among different ethnic groups, with individuals with CVD having a higher likelihood of experiencing sleep disturbance and burnout. Significant differences in burnout and stress were observed between individuals with and without CVD in Kyrgyz and East European ethnic groups.
FRONTIERS IN PUBLIC HEALTH
(2021)
Review
Food Science & Technology
Hadis Mozaffari, Zeinab Hosseini, Jacynthe Lafreniere, Annalijn I. Conklin
Summary: The role of dietary diversity in chronic disease or survival remains controversial. This meta-analysis found an inverse association between total dietary diversity and all-cause mortality, as well as a potential benefit in reducing incident CVD. Consuming a variety of healthy foods showed a lower risk of all-cause mortality. More robust research is needed to confirm the associations.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Nutrition & Dietetics
Pu-Jun Fang, Ping-Hsuan Kuo, Wei-Liang Chen, Tung-Wei Kao, Li-Wei Wu, Hui-Fang Yang, Tao-Chun Peng
Summary: This study investigated the early changes in cardiovascular health (CVH) among young Asian adults and the association between CVH metrics and sociodemographic variables. The results showed that the prevalence of ideal CVH metrics gradually decreased with age. Higher educational attainment and unmarried status were associated with a greater prevalence of ideal CVH metrics regardless of sex, but early CVH changes differed by sex, education level, and marital status. Effective health promotion programs are needed to maintain CVH metrics among young adults.
Article
Cardiac & Cardiovascular Systems
Xiaobo Ding, Xiaozhen Wang, Jing Wu, Manli Zhang, Meizi Cui
Summary: This meta-analysis found that a higher TyG index is independently associated with an increased incidence of ASCVDs, CAD, and stroke in individuals without ASCVDs at baseline. Subgroup analyses suggested no significant impact of age, sex, or diabetic status on this association.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Ronald B. Goldberg, Trevor J. Orchard, Jill P. Crandall, Edward J. Boyko, Matthew Budoff, Dana Dabelea, Kishore M. Gadde, William C. Knowler, Christine G. Lee, David M. Nathan, Karol Watson, Marinella Temprosa
Summary: The study found that neither lifestyle intervention nor metformin reduced the incidence of major cardiovascular events over a 21-year period, despite their long-term diabetes prevention effects. It is possible that the provision of group lifestyle intervention to all participants, extensive use of statin and antihypertensive agents outside the study, and a decrease in the use of study metformin over time may have diluted the effects of these interventions.
Article
Cardiac & Cardiovascular Systems
Christoph Hochsmann, James L. Dorling, Corby K. Martin, Robert L. Newton, John W. Apolzan, Candice A. Myers, Kara D. Denstel, Emily F. Mire, William D. Johnson, Dachuan Zhang, Connie L. Arnold, Terry C. Davis, Vivian Fonseca, Carl J. Lavie, Eboni G. Price-Haywood, Peter T. Katzmarzyk
Summary: A pragmatic ILI delivered in primary care setting produced clinically relevant improvements in cardiometabolic health in underserved population over 24 months, including significant weight loss and improvements in blood glucose, cholesterol levels.
Article
Multidisciplinary Sciences
Nuzulul Kurniansyah, Matthew O. Goodman, Alyna T. Khan, Jiongming Wang, Elena Feofanova, Joshua C. Bis, Kerri L. Wiggins, Jennifer E. Huffman, Tanika Kelly, Tali Elfassy, Xiuqing Guo, Walter Palmas, Henry J. Lin, Shih-Jen Hwang, Yan Gao, Kendra Young, Gregory L. Kinney, Jennifer A. Smith, Bing Yu, Simin Liu, Sylvia Wassertheil-Smoller, JoAnn E. Manson, Xiaofeng Zhu, Yii-Der Ida Chen, I-Te Lee, C. Charles Gu, Donald M. Lloyd-Jones, Sebastian Zoellner, Myriam Fornage, Charles Kooperberg, Adolfo Correa, Bruce M. Psaty, Donna K. Arnett, Carmen R. Isasi, Stephen S. Rich, Robert C. Kaplan, Susan Redline, Braxton D. Mitchell, Nora Franceschini, Daniel Levy, Jerome I. Rotter, Alanna C. Morrison, Tamar Sofer
Summary: This study evaluates the performance and limitations of polygenic risk scores (PRSs) for multiple blood pressure phenotypes in diverse population groups. The authors compare different methods to construct PRSs, including clumping-and-thresholding (PRSice2) and LD-based (LDPred2) approaches. They find that PRS-CSx, a weighted sum of PRSs developed from multiple independent GWAS, performs best across all race/ethnic backgrounds. Stratified analysis shows that PRSs are more predictive of blood pressure in females, individuals without obesity, and middle-aged individuals.
NATURE COMMUNICATIONS
(2023)
Review
Clinical Neurology
Daniel Rapp, Sebastian Michels, Jakob Schoepe, Lukas Schwingshackl, Hayrettin Tumani, Makbule Senel
Summary: This study found that there is an association between multiple sclerosis (MS) and heart diseases, such as myocardial infarction and heart failure, with a more pronounced risk among women and younger individuals. However, no association was found between MS and ischemic heart disease or bradycardia. Additionally, a lower risk of atrial fibrillation was observed in people with MS, although the certainty of evidence was rated as very low.
MULTIPLE SCLEROSIS AND RELATED DISORDERS
(2021)
Article
Peripheral Vascular Disease
Kosuke Inoue, Tamara Horwich, Roshni Bhatnagar, Karan Bhatt, Deena Goldwater, Teresa Seeman, Karol E. Watson
Summary: Higher levels of urinary stress hormones were associated with an increased risk of incident hypertension in this multiethnic population study. Urinary cortisol levels were also found to be associated with an increased risk of incident cardiovascular events. These findings suggest a potential important role of stress hormones in the prevention and treatment of hypertension and cardiovascular diseases.
Article
Nutrition & Dietetics
Yu-Jie Liu, Meng-Yuan Miao, Jia-Min Wang, Quan Tang, Wen-Wen Han, Yi-Ping Jia, Hao-Wei Tao, Yan Zheng, Rob M. van Dam, Li-Qiang Qin, Guo-Chong Chen
Summary: The relationship between coffee consumption and diabetes-related vascular complications is examined in this study. Moderate coffee consumption (2-4 cups/day) is associated with a lower risk of various cardiovascular diseases and chronic kidney disease in individuals with type 2 diabetes who have never smoked.
Article
Public, Environmental & Occupational Health
Felix P. Chilunga, Lenny Stoeldraijer, Charles Agyemang, Karien Stronks, Carel Harmsen, Anton E. Kunst
Summary: By studying the association between migration background and COVID-19 deaths in the Netherlands, it was found that populations with a migration background were more likely to die from COVID-19 throughout the pandemic compared to the Dutch origin population, with the differences becoming larger in the second wave. Despite the introduction of COVID-19 prevention measures targeted at populations with a migration background, the higher risk of COVID-19 deaths persisted in the second wave.
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH
(2023)
Article
Clinical Neurology
Isabelle Glans, Emily Sonestedt, Katarina Nagga, Anna-Marta Gustavsson, Esther Gonzalez-Padilla, Yan Borne, Erik Stomrud, Olle Melander, Peter M. Nilsson, Sebastian Palmqvist, Oskar Hansson
Summary: This study aimed to investigate whether adherence to conventional dietary recommendations or to a modified Mediterranean diet are associated with a subsequent lower risk of developing all-cause dementia, Alzheimer disease (AD), vascular dementia (VaD), or with future accumulation of AD-related beta-amyloid (A beta) pathology. The results showed that adherence to either conventional dietary recommendations or a modified Mediterranean diet did not significantly lower the risk of developing dementia or AD pathology.
Article
Medicine, General & Internal
Huiping Li, Yan Borne, Yaogang Wang, Emily Sonestedt
Summary: This study aimed to investigate the association between starch intake and AMY1 copy number and risk of cardiovascular disease (CVD) and mortality. The study found a U-shaped association between starch intake and risk of CVD and all-cause mortality, but no significant association was found between AMY1 copy number and CVD risk. Several plasma proteins associated with starch intake were identified.
Article
Cardiac & Cardiovascular Systems
Benjamin P. van Nieuwenhuizen, Hanno L. Tan, Marieke T. Blom, Anton E. Kunst, Irene G. M. van Valkengoed
Summary: Previous studies have shown that lower socioeconomic groups have a higher risk of out-of-hospital cardiac arrest (OHCA). However, the extent of these inequalities is uncertain due to the limitations of previous study designs. This large-scale longitudinal study provides new evidence for a significant association between income and OHCA risk across different age and sex groups.
CIRCULATION-CARDIOVASCULAR QUALITY AND OUTCOMES
(2023)
Article
Public, Environmental & Occupational Health
Shunming Zhang, Huiping Li, Gunnar Engstrom, Kaijun Niu, Lu Qi, Yan Borne, Emily Sonestedt
Summary: The study found that higher intake of non-fermented milk was associated with increased risks of cardiovascular disease (CVD) and CVD mortality, while higher intake of fermented milk was associated with decreased risks of CVD and CVD mortality. The genotype associated with higher milk intake was also linked to higher risks of coronary heart disease (CHD) and CVD. Additionally, non-fermented milk intake was associated with leptin and HDL levels, while no associations were found between fermented milk intake or LCT-13910 C/T genotype and plasma proteins or lipoprotein subfractions.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Endocrinology & Metabolism
Jazmin Castaneda, Mercedes Gil-Lespinard, Enrique Almanza-Aguilera, Fjorida Llaha, Jesus-Humberto Gomez, Nicola Bondonno, Anne Tjonneland, Kim Overvad, Verena Katzke, Matthias B. Schulze, Giovanna Masala, Claudia Agnoli, Maria Santucci de Magistris, Rosario Tumino, Carlotta Sacerdote, Guri Skeie, Magritt Brustad, Cristina Lasheras, Esther Molina-Montes, Maria-Dolores Chirlaque, Aurelio Barricarte, Emily Sonestedt, Marisa da Silva, Ingegerd Johansson, Johan Hultdin, Anne M. May, Nita G. Forouhi, Alicia K. Heath, Heinz Freisling, Elisabete Weiderpass, Augustin Scalbert, Raul Zamora-Ros
Summary: This study aimed to evaluate the associations between the intake of total polyphenols, polyphenol classes, and subclasses and body weight change over 5 years. The results showed an inverse association between total flavonoid intake and body weight change, and positive associations between total polyphenol and hydroxycinnamic acid intake and body weight gain. However, the positive association between hydroxycinnamic acid intake and body weight gain was only found in coffee consumers, not in coffee nonconsumers.
Article
Cardiac & Cardiovascular Systems
Renee J. Burger, Sanne J. Gordijn, Renee Bolijn, Annemarie Reilingh, Eric P. Moll Van Charante, Bert-Jan H. van den Born, Christianne J. M. De Groot, Anita C. J. Ravelli, Henrike Galenkamp, Irene G. M. Van Valkengoed, Wessel Ganzevoort
Summary: This study found that pregnancy complications are associated with a higher risk of heart disease later in life for women of different ethnic backgrounds. However, these complications do not significantly improve the prediction of prevalent cardiovascular disease risk factors when added to traditional eligibility criteria for screening.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Critical Care Medicine
R. L. A. Smits, S. T. F. Sodergren, H. van Schuppen, F. Folke, M. Ringh, M. Jonsson, E. Motazedi, I. G. M. van Valkengoed, H. L. Tan
Summary: It was found that women have less favorable resuscitation characteristics than men. The study investigated the performance of the Advanced Life Support Termination of Resuscitation rule (ALS-TOR) in both women and men, and explored whether adding or removing criteria improved classification into survivors and non-survivors. The results showed that the ALS-TOR has high specificity and low miss rate for predicting 30-day survival in both women and men.
Article
Rheumatology
Rebecka Teresia Backlund, Isabel Drake, Ulf Bergstrom, Michele Compagno, Emily Sonestedt, Carl Turesson
Summary: This study found that adherence to the recommended intake level of dietary fiber is independently associated with a decreased risk of RA, while overall diet quality is not associated with RA risk.
Article
Immunology
Sophie L. Campman, Gwen van Rossem, Anders Boyd, Liza Coyer, Janke Schinkel, Charles Agyemang, Henrike Galenkamp, Anitra D. M. Koopman, Tjalling Leenstra, Maarten Schim van der Loeff, Eric P. Moll van Charante, Bert-Jan H. van den Born, Anja Lok, Arnoud Verhoeff, Aeilko H. Zwinderman, Suzanne Jurriaans, Karien Stronks, Maria Prins
Summary: This study investigated the intent to vaccinate against SARS-CoV-2 and its determinants in six ethnic groups in Amsterdam, the Netherlands. The results showed lower intent to vaccinate in all ethnic groups except for the Dutch group. Common determinants of lower vaccination intent across most ethnic groups were being female, believing that COVID-19 is exaggerated in the media, and being <45 years of age. These findings are important for shaping vaccination interventions and campaigns.
Article
Nutrition & Dietetics
Justine Dukuzimana, Suzanne Janzi, Caroline Habberstad, Shunming Zhang, Yan Borne, Emily Sonestedt
Summary: This study investigates the association between dairy consumption and the risk of major adverse coronary events and stroke. The results suggest that very high intakes of non-fermented milk are associated with an increased risk of major adverse coronary events, while moderate intakes of fermented milk are associated with a lower risk. Additionally, intakes of cheese (in women) and butter are inversely associated with the risk of major adverse coronary events. No clear associations were found between any of the dairy products and stroke risk.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Nutrition & Dietetics
Michaela Ramstedt, Suzanne Janzi, Kjell Olsson, Esther Gonzalez-Padilla, Stina Ramne, Yan Borne, Ulrika Ericson, Emily Sonestedt
Summary: Carbohydrate quality, especially the amount of fiber and free sugar, may play a crucial role in reducing the risk of type 2 diabetes (T2D). This study explored the association between four different predefined carbohydrate quality indices and T2D risk. The results suggest that a diet high in fiber and moderate in free sugar, relative to total carbohydrate intake, is associated with a lower risk of T2D.
Article
Public, Environmental & Occupational Health
Liliya Leopold, Irene G. M. van Valkengoed, Henriette Engelhardt
Summary: This study used data from the English Longitudinal Study of Aging to investigate the impact of underreporting on the cumulative advantage and disadvantage hypothesis. The results showed that self-reported measures underestimated the prevalence of hypertension and diabetes. The associations between underreporting and the main constructs in tests of the hypothesis varied, but the conclusions about the hypothesis were not affected.
SOCIAL SCIENCE & MEDICINE
(2023)
Meeting Abstract
Obstetrics & Gynecology
Renee J. Burger, Sanne J. Gordijn, Renee Bolijn, Annemarie Y. Reilingh, Eric P. Moll Van Charante, Bert-Jan H. van den Born, Christianne J. de Groot, Anita C. Ravelli, Henrike Galenkamp, Irene G. van Valkengoed, Wessel Ganzevoort
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Meeting Abstract
Obstetrics & Gynecology
Renee J. Burger, Hannelore Delagrange, Irene G. van Valkengoed, Christianne J. de Groot, Bert-Jan H. van den Born, Sanne J. Gordijn, Wessel Ganzevoort
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
